Product image of Milgamma 100 (Benfotiamine, Pyridoxine Hydrochloride) supplied by GNH India

Milgamma 100

Active Ingredient:
Benfotiamine, Pyridoxine Hydrochloride
Origin:
EU

Milgamma 100 (Benfotiamine, Pyridoxine Hydrochloride)

Benfotiamine and Pyridoxine Hydrochloride, the active ingredients in Milgamma 100, are nutrition supplements presented as an oral dosage form for oral use. They are intended to support nerve health and normal vitamin B metabolism.
GNH India supplies Milgamma 100 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wörwag Pharma Gmbh & Co. Kg

1
Pack/s
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Indications & Clinical Uses

  • Milgamma 100 combines benfotiamine and pyridoxine, which act on nerve function and vitamin B metabolism.
  • Diabetic peripheral neuropathy: helps reduce symptoms of nerve discomfort associated with high glucose levels.
  • Vitamin B1 (thiamine) deficiency: restores thiamine status in individuals with low levels.
  • Vitamin B6 (pyridoxine) deficiency: corrects pyridoxine insufficiency and supports amino‑acid metabolism.

How It Works

  • Benfotiamine is a lipid‑soluble thiamine pro‑drug that readily crosses cell membranes and is converted to thiamine diphosphate, enhancing glucose metabolism and reducing formation of advanced glycation end‑products. Pyridoxine hydrochloride provides vitamin B6, a cofactor for enzymes involved in amino‑acid transamination, neurotransmitter synthesis, and hemoglobin formation, thereby supporting nerve function and metabolic processes.

Side Effects

Milgamma 100 is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or mild stomach upset
  • Headache
  • Transient skin rash or itching
  • Dizziness
  • Mild fatigue

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Stevens‑Johnson syndrome or other severe skin eruptions
  • Significant liver enzyme elevation
  • Hematologic abnormalities such as leukopenia
  • Persistent vomiting or severe gastrointestinal distress

Precautions & Warnings

  • Before using Milgamma 100, consider the following safety measures.
  • Assess vitamin B status: evaluate baseline thiamine and pyridoxine levels when possible.
  • Monitor for neuropathy: observe any changes in nerve symptoms during therapy.
  • Avoid in known hypersensitivity: discontinue if allergic signs appear.
  • Use caution in renal impairment: adjust use if kidney function is reduced.
  • Pregnancy and lactation: safety not established; consult a healthcare professional.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Milgamma 100 may interact with certain medicines; review the following categories.

Major Interactions (Avoid)

  • Levodopa: pyridoxine can diminish levodopa efficacy.
  • Phenobarbital and other enzyme‑inducing anticonvulsants: may increase vitamin B6 metabolism.
  • High‑dose thiamine therapy: concurrent use can lead to excess thiamine levels.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may alter vitamin B status.
  • Diuretics: can affect electrolyte balance and vitamin excretion.
  • Alcohol consumption: increases risk of vitamin B deficiency and may potentiate side effects.

Frequently Asked Questions

Milgamma 100 is an oral nutrition supplement that combines benfotiamine and pyridoxine to support normal nerve function and address deficiencies of vitamin B1 (thiamine) and vitamin B6 (pyridoxine). It is commonly used in the management of diabetic peripheral neuropathy and in individuals with documented vitamin B deficiencies.

Benfotiamine is a lipid‑soluble derivative of thiamine that easily enters cells and is converted to the active cofactor thiamine diphosphate. This cofactor participates in carbohydrate metabolism, helping to reduce harmful glucose‑derived metabolites and protecting nerve cells from oxidative stress.

The appropriate dose of Milgamma 100 is determined by a qualified healthcare professional based on the individual’s clinical condition, age, and nutritional status. Prescribers select the dosage that best matches the therapeutic goal, and patients should follow the specific instructions provided by their clinician.

Safety data for Milgamma 100 in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting the supplement.

To place an order, submit an enquiry on the Milgamma 100 product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Milgamma 100 uniquely combines benfotiamine, a highly bioavailable thiamine pro‑drug, with pyridoxine hydrochloride, offering both thiamine and vitamin B6 in a single formulation. Conventional vitamin B1 or B6 tablets may contain water‑soluble forms that have lower cellular uptake, whereas benfotiamine provides enhanced tissue penetration, potentially delivering greater metabolic benefits for nerve health.

Store Milgamma 100 at temperatures below 25 °C in its original container, protecting it from moisture, heat, and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive humidity, which could affect tablet integrity.

Milgamma 100 is taken orally with a full glass of water. It may be taken with or without food, although some users find it easier on the stomach when taken with meals. Follow the dosing instructions provided by the prescribing clinician.

The most serious risks include severe allergic reactions such as anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and significant liver enzyme elevations. If any signs of a serious reaction appear—such as difficulty breathing, widespread rash, or jaundice—medical attention should be sought immediately.

Milgamma 100 should be avoided by individuals with known hypersensitivity to benfotiamine, pyridoxine, or any excipients in the product. It is also contraindicated in patients with severe renal impairment unless supervised by a physician, and it should be used with caution in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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