Product image of Milgamma N (Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride) supplied by GNH India

Milgamma N

Active Ingredient:
Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride
Origin:
EU

Milgamma N (Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride)

Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride, the active ingredients in Milgamma N, are a Vitamin B complex supplement presented as an oral tablet for oral use. It supports the correction of vitamin B1, B6 and B12 deficiencies and may help alleviate peripheral neuropathy associated with these deficits.

GNH India supplies Milgamma N as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wörwag Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Milgamma N, a vitamin B complex supplement, is used to address deficiencies in the B‑vitamin pathway and related neuropathic conditions.

  • Vitamin B1 deficiency: helps restore thiamine levels and supports carbohydrate metabolism.
  • Vitamin B6 deficiency: aids pyridoxine repletion and neurotransmitter synthesis.
  • Vitamin B12 deficiency: contributes to cobalamin replenishment and normal red blood cell formation.
  • Peripheral neuropathy: may alleviate symptoms linked to nerve dysfunction caused by B‑vitamin deficits.

How It Works

  • Benfotiamine, a lipid‑soluble thiamine derivative, cyanocobalamin, a synthetic cobalamin, and pyridoxine hydrochloride, vitamin B6, act as essential cofactors for enzymes involved in carbohydrate metabolism, amino‑acid processing and myelin synthesis. They enhance transketolase, aminotransferases and methylmalonyl‑CoA mutase activity, thereby supporting neuronal function and energy production at the cellular level.

Side Effects

Milgamma N may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild stomach upset.
  • Headache: transient discomfort.
  • Skin rash: mild erythema.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Hemolytic anemia: rare blood disorder.

Precautions & Warnings

Before using Milgamma N, consider the following precautions.

  • Assess deficiency: confirm vitamin B1, B6 or B12 deficiency prior to therapy.
  • Monitor neuropathy: evaluate symptom changes and watch for worsening.
  • Renal impairment: use with caution in patients with severe kidney disease.
  • Pregnancy and lactation: prescribe only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original packaging.

Avoid Interactions

Milgamma N can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Antimetabolites (e.g., methotrexate): may reduce vitamin efficacy.
  • High‑dose vitamin C: can interfere with B‑vitamin absorption.
  • Phenobarbital: may increase metabolism, lowering vitamin levels.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may alter vitamin‑binding proteins.
  • Diuretics: can affect electrolyte balance and B‑vitamin status.
  • Antacids containing aluminum or magnesium: may decrease pyridoxine absorption.

Frequently Asked Questions

Milgamma N is a vitamin B complex supplement that provides bioavailable forms of vitamins B1 (benfotiamine), B6 (pyridoxine hydrochloride) and B12 (cyanocobalamin). It is used to correct deficiencies of these vitamins and to support patients with peripheral neuropathy linked to such deficiencies.

Benfotiamine supplies thiamine that participates in carbohydrate metabolism, cyanocobalamin provides cobalamin needed for red blood cell formation and nerve health, and pyridoxine acts as a cofactor for amino‑acid metabolism and neurotransmitter synthesis. Together they enhance enzymatic pathways essential for neuronal function and energy production.

The appropriate dose of Milgamma N is determined by the prescribing healthcare professional based on the individual’s deficiency status, age, weight and clinical condition. Patients should follow the prescriber’s instructions and not alter the dosage without medical advice.

Safety data for Milgamma N in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Milgamma N, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Milgamma N combines a lipid‑soluble thiamine derivative (benfotiamine) with standard cyanocobalamin and pyridoxine, offering potentially higher bioavailability of vitamin B1 compared with plain thiamine salts. Its composition is similar to other B‑complex formulations but the specific inclusion of benfotiamine may provide added benefit for carbohydrate metabolism and nerve support.

Milgamma N should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct light, and ensure the package is tightly closed to maintain stability.

Milgamma N is taken orally, typically with water. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional.

Serious but rare adverse reactions include anaphylaxis, Stevens‑Johnson syndrome and hemolytic anemia. Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, widespread skin rash, blistering, or sudden onset of fatigue and jaundice.

Milgamma N is contraindicated in individuals with known hypersensitivity to any of its ingredients. Patients with severe renal impairment should use it only under medical supervision, and pregnant or breastfeeding women should only take it when clearly indicated by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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