Product image of Milgamma N (Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride) supplied by GNH India

Milgamma N

Active Ingredient:
Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride
Origin:
EU

Milgamma N (Benfotiamine, Cyanocobalamin, Pyridoxine Hydrochloride)

Benfotiamine, Cyanocobalamin, and Pyridoxine Hydrochloride, the active ingredients in Milgamma N, are vitamins presented as an oral tablet for oral use. They are combined to support nerve health and address vitamin B deficiencies.
GNH India supplies Milgamma N as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wörwag Pharma Gmbh & Co. Kg

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Indications & Clinical Uses

Milgamma N is used to support conditions related to nerve function and vitamin B deficiencies.

  • Vitamin B12 deficiency: restores normal red blood cell formation and neurological function.
  • Peripheral neuropathy: helps reduce symptoms such as tingling, burning and numbness.
  • Diabetic neuropathy: may mitigate nerve damage associated with chronic high blood glucose levels.

How It Works

  • Benfotiamine, a lipid‑soluble thiamine derivative, enhances transketolase activity and reduces formation of advanced glycation end‑products, protecting nerve tissue. Cyanocobalamin is converted to methylcobalamin and adenosylcobalamin, co‑enzymes essential for DNA synthesis, myelin formation and homocysteine metabolism. Pyridoxine is metabolised to pyridoxal‑5′‑phosphate, a co‑factor for neurotransmitter synthesis and amino‑acid metabolism, collectively supporting neuronal health and metabolic balance.

Side Effects

Milgamma N is generally well tolerated, but some users may experience mild reactions.

Common Side Effects

  • Nausea: occasional stomach upset after ingestion.
  • Abdominal discomfort: mild cramps or bloating.
  • Headache: transient mild headache.
  • Skin rash: mild erythema or itching.
  • Metallic taste: brief aftertaste.
  • Diarrhoea: loose stools in sensitive individuals.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare severe skin eruption.
  • Worsening neuropathy: unexpected increase in nerve pain.
  • Blood dyscrasias: abnormal blood counts.
  • Liver enzyme elevation: signs of hepatic stress.
  • Thrombocytopenia: low platelet count, increasing bleeding risk.

Precautions & Warnings

Before using Milgamma N, consider the following safety measures.

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Breastfeeding: discuss with a physician as vitamins may pass to infant.
  • Renal impairment: dosage may need adjustment under medical guidance.
  • Drug interactions: review concomitant medications for potential conflicts.
  • Allergies: avoid if known hypersensitivity to any component.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Milgamma N may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Methotrexate: increased risk of hematologic toxicity.
  • Anticonvulsants (e.g., carbamazepine): may accelerate pyridoxine metabolism, reducing efficacy.
  • Tetracycline antibiotics: can chelate with B vitamins, decreasing absorption.

Moderate Interactions (Monitor Closely)

  • Metformin: may exacerbate vitamin B12 deficiency; monitor levels.
  • Proton pump inhibitors: can reduce B12 absorption over long term.
  • Alcohol: excessive intake may increase neuropathy risk while on B‑vitamin therapy.

Frequently Asked Questions

Milgamma N is an oral vitamin supplement that combines benfotiamine, cyanocobalamin (vitamin B12) and pyridoxine (vitamin B6). It is used to support nerve health, help manage peripheral and diabetic neuropathy, and correct deficiencies of the B‑vitamins involved in red blood cell formation and neurological function.

Benfotiamine is a lipid‑soluble form of thiamine that easily enters cells and boosts the activity of the enzyme transketolase. This reduces the accumulation of harmful metabolic by‑products such as advanced glycation end‑products, thereby protecting nerve cells from damage associated with high glucose levels.

The specific dose of Milgamma N is determined by the prescribing healthcare professional based on the individual’s condition, age, weight and other medications. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for Milgamma N in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential benefits and risks with their doctor before starting the product.

To order Milgamma N, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and import documentation.

Milgamma N combines three specific B‑vitamins—benfotiamine, cyanocobalamin and pyridoxine—into a single tablet, offering a targeted approach for neuropathy and B‑vitamin deficiency. Many other supplements provide individual vitamins or generic B‑complex blends, which may not deliver the same high‑bioavailability forms or synergistic effects found in Milgamma N.

Milgamma N should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct light, and ensure the container is tightly closed to maintain product stability.

Milgamma N is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless directed by a healthcare professional. It can be taken with or without food, depending on the prescriber’s recommendation.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, skin conditions like Stevens‑Johnson syndrome, and hematologic abnormalities such as blood dyscrasias. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, widespread rash, or unexplained bruising.

Milgamma N should be avoided by individuals with known hypersensitivity to any of its ingredients. Patients with severe renal impairment, uncontrolled metabolic disorders, or those taking medications that have major interactions (e.g., methotrexate) should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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