Product image of Minims Atropinesulfaat 10 Mg/Ml Oogdruppels, Oplossing (Atropine Sulfate) supplied by GNH India

Minims Atropinesulfaat 10 Mg/Ml Oogdruppels, Oplossing

Active Ingredient:
Atropine Sulfate
Origin:
EU

Minims Atropinesulfaat 10 Mg/Ml Oogdruppels, Oplossing (Atropine Sulfate)

Atropine sulfate, the active ingredient in Minims Atropinesulfaat 10 Mg/Ml Oogdruppels, Oplossing, is an anticholinergic presented as a 10 mg/mL ophthalmic solution for ocular use. It provides pupil dilation and cycloplegia for diagnostic eye examinations and helps manage anterior uveitis.

GNH India supplies Minims Atropinesulfaat 10 Mg/Ml Oogdruppels, Oplossing as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Atropine sulfate is used in ophthalmology to achieve controlled dilation and cycloplegia for various diagnostic and therapeutic purposes.

  • Mydriasis for diagnostic eye examinations: provides sustained pupil dilation to facilitate fundus evaluation.
  • Cycloplegia: temporarily paralyzes accommodation to allow accurate refraction measurements.
  • Anterior uveitis: reduces intra‑ocular inflammation and associated pain.

How It Works

  • Atropine sulfate acts as a competitive antagonist of muscarinic acetylcholine receptors in the iris sphincter and ciliary body. By blocking these receptors, it prevents parasympathetic-mediated contraction, leading to relaxation of the sphincter muscle (pupil dilation) and ciliary muscle (cycloplegia), which are useful for ocular examinations and certain inflammatory conditions.

Side Effects

Common Side Effects

  • Blurred vision: temporary loss of visual clarity after instillation.
  • Photophobia: increased sensitivity to light due to dilated pupils.
  • Ocular discomfort: mild irritation or burning sensation.
  • Redness of the eye: conjunctival hyperemia.

Serious or Rare Side Effects

  • Acute angle‑closure glaucoma: sudden rise in intra‑ocular pressure.
  • Severe allergic reaction (anaphylaxis): systemic hypersensitivity.
  • Persistent mydriasis: prolonged pupil dilation beyond expected duration.
  • Corneal edema: swelling of the cornea affecting vision.

Precautions & Warnings

Before using atropine eye drops, consider the following precautions.

  • Assess intra‑ocular pressure: patients with narrow‑angle glaucoma may be at risk.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Use caution in pediatric patients: systemic absorption can be higher.
  • Monitor for systemic anticholinergic effects: especially in elderly or those on other anticholinergics.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Atropine sulfate may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent mydriatics (e.g., phenylephrine): may cause excessive dilation.
  • Systemic anticholinergics (e.g., antihistamines): increase overall anticholinergic load.
  • MAO inhibitors: can potentiate systemic anticholinergic effects.

Moderate Interactions (Monitor Closely)

  • Topical beta‑blockers for glaucoma: reduced efficacy when combined.
  • Other cycloplegic agents (e.g., cyclopentolate): additive cycloplegia.
  • NSAID eye drops: may increase risk of corneal toxicity.

Frequently Asked Questions

Minims Atropinesulfaat 10 Mg/Ml Oogdruppels is an ophthalmic solution containing atropine sulfate. It is used to dilate the pupil (mydriasis) and temporarily paralyze accommodation (cycloplegia) for diagnostic eye examinations, and to help manage inflammation in anterior uveitis.

Atropine sulfate blocks muscarinic acetylcholine receptors in the iris sphincter and ciliary body. This inhibition prevents parasympathetic contraction, causing the pupil to dilate and the ciliary muscle to relax, which facilitates eye examinations and reduces inflammatory responses.

The prescribed dose of Minims Atropinesulfaat is determined by the treating ophthalmologist based on the specific indication, patient age, and clinical response. The prescriber will provide exact instructions on the number of drops and frequency of administration.

The safety of atropine sulfate eye drops in pregnancy or lactation has not been definitively established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and under the guidance of a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Atropine sulfate provides a longer duration of pupil dilation and cycloplegia compared with shorter‑acting agents such as tropicamide. This makes it useful when prolonged dilation is needed, but it may also increase the risk of prolonged visual disturbances and requires careful monitoring.

Store the ophthalmic solution at ambient temperature, ideally below 25 °C. Keep the bottle in its original packaging, protect it from direct light and moisture, and ensure the cap is tightly closed to maintain sterility.

The solution is applied topically to the conjunctival sac of the eye. The prescriber will instruct the patient on the number of drops per eye and the frequency, typically using a sterile dropper to avoid contamination.

Serious risks include acute angle‑closure glaucoma, severe allergic reactions such as anaphylaxis, persistent mydriasis, and corneal edema. Patients should be instructed to seek immediate medical attention if they experience severe eye pain, sudden vision loss, or systemic allergic symptoms.

Patients with known hypersensitivity to atropine sulfate or any excipients in the formulation should avoid use. Individuals with narrow‑angle or uncontrolled glaucoma, and those who have had recent ocular surgery that contraindicates dilation, should not receive this medication without specialist advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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