Product image of Minims Cyclopentolaathydrochloride Bausch + Lomb Ireland Limited (Cyclopentolate Hydrochloride) supplied by GNH India

Minims Cyclopentolaathydrochloride Bausch + Lomb Ireland Limited

Active Ingredient:
Cyclopentolate Hydrochloride
Origin:
EU

Minims Cyclopentolaathydrochloride Bausch + Lomb Ireland Limited (Cyclopentolate Hydrochloride)

Cyclopentolate Hydrochloride, the active ingredient in Minims Cyclopentolaathydrochloride Bausch + Lomb Ireland Limited, is an anticholinergic (muscarinic antagonist) presented as an ophthalmic solution for ocular use. It produces reversible pupil dilation and temporary loss of accommodation, facilitating diagnostic eye examinations and accurate refraction measurements.
GNH India supplies Minims Cyclopentolaathydrochloride Bausch + Lomb Ireland Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Cyclopentolate Hydrochloride is a mydriatic/cycloplegic agent used in ophthalmic practice.

  • Diagnostic pupil dilation: provides mydriasis for fundus and retinal examinations.
  • Cycloplegic refraction: temporarily paralyzes accommodation to allow precise measurement of refractive error.
  • Anterior uveitis management: used as an adjunct to reduce pain and prevent formation of synechiae.

How It Works

  • Cyclopentolate Hydrochloride acts as a reversible non‑selective antagonist of muscarinic acetylcholine receptors in the iris sphincter and ciliary body. By blocking these receptors, it inhibits parasympathetic tone, leading to relaxation of the sphincter muscle (mydriasis) and ciliary muscle (cycloplegia), thereby dilating the pupil and eliminating accommodation.

Side Effects

Cyclopentolate may cause ocular and systemic reactions.

Common Side Effects

  • Transient stinging or burning sensation on instillation.
  • Blurred vision due to loss of accommodation.
  • Photophobia from prolonged pupil dilation.

Serious or Rare Side Effects

  • Acute angle‑closure glaucoma in predisposed eyes.
  • Systemic anticholinergic toxicity such as dry mouth, tachycardia, or confusion.
  • Allergic reactions including eyelid edema, rash, or conjunctival hyperemia.

Precautions & Warnings

Use of cyclopentolate requires careful assessment of patient risk factors.

  • Contraindication: known hypersensitivity to cyclopentolate or other anticholinergics.
  • Caution: patients with narrow‑angle glaucoma should be evaluated before use.
  • Avoid: routine use in infants and young children unless specifically indicated.
  • Monitor: elderly patients for systemic anticholinergic effects.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Cyclopentolate can interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Systemic anticholinergics (e.g., atropine): additive anticholinergic effects may increase toxicity.
  • Adrenergic agonists (e.g., phenylephrine): combined use may precipitate a rise in intra‑ocular pressure.

Moderate Interactions (Monitor Closely)

  • Topical NSAIDs: may increase ocular irritation when used together.
  • Beta‑blocker eye drops: monitor intra‑ocular pressure for additive effects.
  • Oral antihistamines: may enhance systemic anticholinergic symptoms such as dry mouth or dizziness.

Frequently Asked Questions

Minims Cyclopentolate is an ophthalmic solution containing cyclopentolate hydrochloride. It is used to dilate the pupil (mydriasis) and temporarily paralyze the eye's focusing ability (cycloplegia) during diagnostic examinations, refraction testing, and as an adjunct in managing anterior uveitis.

Cyclopentolate hydrochloride blocks muscarinic acetylcholine receptors in the iris sphincter and ciliary body. This antagonism relaxes the sphincter muscle, causing pupil dilation, and paralyzes the ciliary muscle, eliminating accommodation, which together facilitate eye examinations and accurate refractive measurements.

The specific dose and frequency of cyclopentolate are determined by the prescribing eye care professional based on the clinical indication, patient age, and ocular condition. The prescriber will select the appropriate number of drops and timing for each examination.

Safety data for cyclopentolate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Cyclopentolate is an anticholinergic that produces both mydriasis and cycloplegia, whereas phenylephrine is an adrenergic agonist that primarily dilates the pupil without affecting accommodation. Cyclopentolate provides a longer duration of cycloplegia, making it preferable for refraction, while phenylephrine is often used when only brief dilation is needed.

Store the ophthalmic solution at ambient temperature, preferably below 25 °C, in its original container. Protect it from direct light, moisture, and extreme temperatures. Keep the bottle tightly closed when not in use and discard any solution that appears discolored or contaminated.

Minims Cyclopentolate is applied topically to the eye as prescribed. Typically, one or more drops are instilled into the conjunctival sac of the target eye(s) using a sterile technique. The patient should be instructed to avoid touching the dropper tip to the eye or surrounding tissues.

Serious risks include acute angle‑closure glaucoma in susceptible individuals, systemic anticholinergic toxicity (e.g., severe dry mouth, tachycardia, confusion), and allergic reactions such as eyelid swelling or rash. Any sudden eye pain, vision loss, or systemic symptoms should prompt immediate medical evaluation.

Cyclopentolate should not be used in patients with a known hypersensitivity to the drug or other anticholinergics, and it is contraindicated in individuals with narrow‑angle or acute angle‑closure glaucoma unless specifically directed by an ophthalmologist. Caution is also advised in infants, young children, and the elderly.

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GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

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