Product image of Minims Cyclopentolathydrochlorid Bausch + Lomb Ireland Limited (Cyclopentolate Hydrochloride) supplied by GNH India

Minims Cyclopentolathydrochlorid Bausch + Lomb Ireland Limited

Active Ingredient:
Cyclopentolate Hydrochloride
Origin:
EU

Minims Cyclopentolathydrochlorid Bausch + Lomb Ireland Limited (Cyclopentolate Hydrochloride)

Cyclopentolate Hydrochloride, the active ingredient in Minims Cyclopentolathydrochlorid Bausch + Lomb Ireland Limited, is an antimuscarinic (anticholinergic) ophthalmic solution presented as an eye drop for ocular use. It produces pupil dilation and paralysis of accommodation to aid diagnostic and therapeutic eye procedures.
GNH India supplies Minims Cyclopentolathydrochlorid Bausch + Lomb Ireland Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Cyclopentolate Hydrochloride is an antimuscarinic ophthalmic agent used to manage conditions that require pupil dilation or accommodation paralysis.

  • Ocular examination: provides mydriasis to facilitate fundoscopy and retinal imaging.
  • Uveitis: induces cycloplegia to reduce pain and prevent formation of synechiae.
  • Refraction testing: creates cycloplegia for accurate measurement of refractive error.

How It Works

  • Cyclopentolate Hydrochloride acts as a competitive antagonist at muscarinic acetylcholine receptors in the iris sphincter and ciliary body. By blocking these receptors, it prevents parasympathetic-mediated constriction of the pupil and accommodation, resulting in sustained mydriasis and cycloplegia that aid ocular assessment and treatment.

Side Effects

Cyclopentolate may cause ocular and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Transient ocular burning or stinging.
  • Conjunctival redness.
  • Blurred vision.
  • Increased intra‑ocular pressure in susceptible individuals.
  • Mild headache.
  • Dry mouth.

Serious or Rare Side Effects

  • Acute angle‑closure glaucoma.
  • Severe allergic reaction such as contact dermatitis or swelling.
  • Systemic anticholinergic toxicity (rare, includes confusion, tachycardia).
  • Persistent mydriasis beyond 24 hours.
  • Vision loss (extremely rare).

Precautions & Warnings

Before using Cyclopentolate, clinicians should consider several safety measures.

  • Assess intra‑ocular pressure: avoid in patients with narrow‑angle glaucoma.
  • Check for hypersensitivity: discontinue if allergic signs appear.
  • Use the lowest effective dose: limit exposure to reduce systemic absorption.
  • Avoid concurrent mydriatics unless directed: may lead to excessive dilation.
  • Pregnancy and lactation: safety unknown; use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Cyclopentolate can interact with other ophthalmic or systemic agents.

Major Interactions (Avoid)

  • Other anticholinergic agents: may increase systemic anticholinergic effects.
  • Miotic agents (e.g., pilocarpine): antagonistic effect reducing mydriasis.

Moderate Interactions (Monitor Closely)

  • Topical beta‑blockers: may affect intra‑ocular pressure control.
  • Systemic antihistamines: can potentiate anticholinergic side effects.
  • Corticosteroid eye drops: may mask signs of increased intra‑ocular pressure.

Frequently Asked Questions

Minims Cyclopentolathydrochlorid contains cyclopentolate hydrochloride, an antimuscarinic eye drop used to dilate the pupil (mydriasis) and temporarily paralyze accommodation (cycloplegia). It facilitates detailed ocular examinations, retinal imaging, and treatment of conditions such as uveitis where cycloplegia is required.

Cyclopentolate blocks muscarinic acetylcholine receptors in the iris sphincter and ciliary body. By preventing parasympathetic signaling, it stops the muscles that constrict the pupil and focus the lens, leading to a widened pupil and loss of accommodation, which are useful for diagnostic and therapeutic purposes.

The dosing regimen for Minims Cyclopentolathydrochlorid is determined by the prescribing ophthalmologist based on the specific clinical need, patient age, and response. The product is supplied as eye drops, and the prescriber will specify the number of drops and frequency.

Safety data for cyclopentolate in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Cyclopentolate provides both mydriasis and cycloplegia, unlike agents such as tropicamide which mainly cause dilation with limited cycloplegic effect. Compared with phenylephrine, cyclopentolate works via antimuscarinic mechanisms rather than adrenergic stimulation, offering a different side‑effect profile and duration of action.

The eye drops should be stored at room temperature, ideally below 25 °C, in the original container. Protect the product from direct light and moisture, and keep the cap tightly closed when not in use to maintain stability.

The medication is applied topically to the eye. The prescriber will instruct the patient to instill the specified number of drops into the conjunctival sac, usually one or two drops per eye, and to keep the eyes closed briefly to enhance absorption.

Serious risks include acute angle‑closure glaucoma, severe allergic reactions such as contact dermatitis, and rare systemic anticholinergic toxicity. Patients should be monitored for signs of increased intra‑ocular pressure, severe eye pain, or systemic symptoms like confusion or rapid heartbeat.

Patients with known hypersensitivity to cyclopentolate or any formulation components, those with narrow‑angle or uncontrolled glaucoma, and individuals in whom the risks of anticholinergic effects outweigh the benefits should avoid using this product. The prescriber will assess suitability on a case‑by‑case basis.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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