Product image of Minims Fenylefrinehydrochloride Bausch + Lomb (Phenylephrine Hydrochloride) supplied by GNH India

Minims Fenylefrinehydrochloride Bausch + Lomb

Active Ingredient:
Phenylephrine Hydrochloride
Origin:
EU

Minims Fenylefrinehydrochloride Bausch + Lomb (Phenylephrine Hydrochloride)

Phenylephrine Hydrochloride, the active ingredient in Minims Fenylefrinehydrochloride Bausch + Lomb, is a sympathomimetic (alpha‑1 adrenergic agonist) presented as an ophthalmic solution for ocular use. It reduces conjunctival redness and is used in adults and children when appropriate.
GNH India supplies Minims Fenylefrinehydrochloride Bausch + Lomb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Phenylephrine Hydrochloride acts as an ocular vasoconstrictor to relieve redness in the following conditions:

  • Conjunctival hyperemia: reduces visible redness by constricting conjunctival blood vessels.
  • Ocular redness: provides temporary relief of eye redness caused by irritation or minor inflammation.
  • Post‑operative ocular irritation: helps diminish redness after minor eye procedures.

How It Works

  • Phenylephrine Hydrochloride selectively stimulates alpha‑1 adrenergic receptors on the smooth muscle of conjunctival blood vessels. This activation triggers vasoconstriction, decreasing blood flow to the ocular surface and thereby reducing the appearance of redness and hyperemia without systemic absorption at therapeutic ocular doses.

Side Effects

Phenylephrine Hydrochloride may cause a range of ocular and systemic reactions.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Transient blurred vision.
  • Mild eye irritation or itching.
  • Temporary increase in intra‑ocular pressure.
  • Mild headache.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling or difficulty breathing.
  • Significant rise in intra‑ocular pressure leading to glaucoma.
  • Corneal edema or ulceration.
  • Persistent ocular pain or redness beyond expected duration.

Precautions & Warnings

Phenylephrine Hydrochloride should be used with caution in the following situations:

  • Narrow‑angle glaucoma: may precipitate angle‑closure attacks.
  • Known hypersensitivity: avoid if allergic to phenylephrine or formulation excipients.
  • Cardiovascular disease: monitor blood pressure as systemic absorption can occur.
  • Pediatric use: safety and efficacy not established in children under a specified age.
  • Exceeding recommended frequency: follow label or prescriber instructions to prevent over‑exposure.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Phenylephrine Hydrochloride can interact with other medications, requiring attention to avoid adverse effects.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Tricyclic antidepressants: additive vasoconstrictive effect.
  • Beta‑blockers: may exacerbate intra‑ocular pressure changes.

Moderate Interactions (Monitor Closely):\n- Other ocular decongestants: cumulative vasoconstriction may increase risk of ischemia.

  • Systemic sympathomimetics: additive systemic cardiovascular effects.
  • Topical anesthetics: potential increase in corneal toxicity.

Frequently Asked Questions

Minims Fenylefrinehydrochloride is an over‑the‑counter ophthalmic solution that temporarily reduces eye redness and conjunctival hyperemia by constricting surface blood vessels. It is commonly used for cosmetic relief of red eyes caused by irritation, minor inflammation, or post‑procedural effects.

Phenylephrine hydrochloride is a selective alpha‑1 adrenergic agonist. When applied to the eye, it binds to alpha‑1 receptors on conjunctival blood‑vessel smooth muscle, causing vasoconstriction. This reduces blood flow to the ocular surface, diminishing the visible redness associated with hyperemia.

The appropriate dose and frequency are determined by the prescribing healthcare professional or according to the product label. Typically, one or two drops are instilled in the affected eye(s) no more than every four to six hours, but exact instructions should be confirmed with a qualified provider.

Safety data for phenylephrine hydrochloride in pregnancy and lactation are limited. Healthcare providers usually weigh potential benefits against unknown risks before recommending use. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using this ophthalmic product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Phenylephrine hydrochloride, the active ingredient in Minims Fenylefrinehydrochloride, is a direct alpha‑1 agonist, offering rapid vasoconstriction. Compared with agents such as naphazoline or tetrahydrozoline, phenylephrine has a similar onset but may have a slightly shorter duration of action and a comparable safety profile when used as directed.

Store Minims Fenylefrinehydrochloride at room temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and discard any solution that appears discolored or contains particles.

The product is administered as an eye drop. After washing hands, tilt the head back, gently pull down the lower eyelid to create a pocket, and place the prescribed number of drops into the conjunctival sac. Close the eye briefly and avoid blinking excessively to allow absorption.

Serious risks include severe allergic reactions such as anaphylaxis, significant elevation of intra‑ocular pressure that could precipitate glaucoma, and corneal complications like edema or ulceration. Patients experiencing intense pain, vision changes, or swelling should discontinue use and seek immediate medical attention.

Individuals with known hypersensitivity to phenylephrine or any formulation component, patients with narrow‑angle or uncontrolled glaucoma, and those taking monoamine oxidase inhibitors or other potent vasoconstrictors should avoid using this product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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