Minims (Fluorescein Sodium)

Fluorescein sodium is a fluorescent dye that adheres to damaged epithelial cells and areas where the tear film is disrupted. When illuminated with cobalt‑blue light, it emits a bright green fluorescence, allowing clinicians to clearly see defects and staining patterns on the ocular surface.

The specific dose and number of drops are determined by the prescribing clinician based on the examination protocol. Typically, a single drop is instilled into the conjunctival sac, and the eye is examined after a brief waiting period.

Safety data for fluorescein sodium in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk to the mother or infant, and the decision should be made by a qualified health professional.

To order Minims, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative to fluorescein sodium is Lissamine Green, which stains devitalized cells rather than intact epithelium. Fluorescein provides rapid, high‑contrast visualization of epithelial defects, while Lissamine is often used for chronic dry‑eye assessment. Choice depends on the clinical objective and physician preference.

Minims should be stored at room temperature below 25 °C, in its original sealed container, protected from direct light and moisture. Do not freeze the solution. Before use, inspect the vial for any discoloration or particulate matter and discard if the product appears compromised.

Minims is applied topically to the eye. The clinician instills a single drop into the lower conjunctival sac, asks the patient to blink gently to spread the dye, and then examines the ocular surface under cobalt‑blue illumination after a brief waiting period.

Serious risks, although rare, include severe allergic reactions such as angioedema or anaphylaxis, and corneal toxicity with prolonged or repeated exposure. Immediate medical attention is required if systemic symptoms like difficulty breathing, swelling, or widespread rash develop.

Minims should be avoided in individuals with a known hypersensitivity to fluorescein sodium or any component of the formulation. Caution is also advised for patients with a history of severe ocular allergies or those who have experienced adverse reactions to similar diagnostic dyes.