Product image of Minims (Fluorescein Sodium, Lidocaine Hydrochloride) supplied by GNH India

Minims

Active Ingredient:
Fluorescein Sodium, Lidocaine Hydrochloride
Origin:
EU

Minims (Fluorescein Sodium, Lidocaine Hydrochloride)

Fluorescein Sodium, the active ingredient in Minims, is a diagnostic dye presented as an ophthalmic solution for ocular use. It stains damaged corneal epithelium allowing visualization, while lidocaine hydrochloride provides topical anesthesia for minor procedures.\n\nGNH India supplies Minims as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

  • Minims, containing fluorescein sodium and lidocaine hydrochloride, is employed in ophthalmic diagnostic and procedural settings.\n\nCorneal epithelial defects: provides fluorescent staining to delineate lesion boundaries.\nForeign body removal: offers topical anesthesia to reduce discomfort during extraction.\nMinor ocular procedures (e.g., tonometry, laser): supplies both anesthesia and enhanced visualization of the ocular surface.

How It Works

  • Fluorescein sodium binds to exposed stromal proteins of damaged corneal epithelium and fluoresces under cobalt‑blue illumination, highlighting defects. Lidocaine hydrochloride penetrates ocular tissues and blocks voltage‑gated sodium channels on peripheral nerve endings, producing reversible loss of sensation and facilitating painless examination or minor intervention.

Side Effects

  • Adverse reactions may occur following ocular administration of Minims.\n\nCommon Side Effects:\n- Transient stinging or burning sensation at the application site.\n- Mild ocular irritation or redness.\n- Temporary blurred vision lasting a few minutes.\n- Increased tearing or lacrimation.\n- Mild conjunctival hyperemia.\n\nSerious or Rare Side Effects:\n- Allergic reaction including rash, swelling, or anaphylaxis.\n- Corneal toxicity leading to persistent epithelial defects.\n- Significant increase in intra‑ocular pressure.\n- Severe ocular inflammation or uveitis.

Precautions & Warnings

  • Before using Minims, consider the following precautions.\n\nAllergy assessment: verify no known hypersensitivity to fluorescein or lidocaine.\nPregnancy: use only if the anticipated benefit justifies potential risk to the fetus.\nBreastfeeding: evaluate possible exposure to the infant and weigh benefits.\nContact lens wearers: remove lenses prior to instillation to avoid staining.\nConcurrent ocular medications: avoid mixing with other anesthetic drops unless directed by a clinician.\nStore at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

  • Minims may interact with other ophthalmic agents.\n\nMajor Interactions (Avoid):\n- Systemic lidocaine‑containing products: may raise systemic lidocaine levels.\n- Topical vasoconstrictors (e.g., phenylephrine): can diminish anesthetic efficacy.\n- Anticholinergic eye drops: may exacerbate pupil dilation effects.\n\nModerate Interactions (Monitor Closely):\n- Other ocular dyes: risk of additive staining or color confusion.\n- Beta‑blocker eye drops: monitor intra‑ocular pressure changes.\n- Antifungal or antibiotic eye preparations: assess for potential irritation when used sequentially.

Frequently Asked Questions

Minims is an ophthalmic solution that combines fluorescein sodium and lidocaine hydrochloride. It is used to stain damaged corneal epithelium for diagnostic visualization and to provide topical anesthesia during minor ocular procedures such as foreign‑body removal, tonometry, or laser treatment.

Fluorescein sodium adheres to exposed proteins on a compromised corneal surface and emits a bright green fluorescence when illuminated with cobalt‑blue light. This contrast highlights epithelial defects, allowing clinicians to assess size, shape, and location of the injury accurately.

The specific dose and frequency of Minims are determined by the prescribing eye‑care professional based on the intended diagnostic or procedural use. The prescriber will decide the volume of drops and timing appropriate for each patient.

Safety data for Minims in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers should discuss individual circumstances with the patient before prescribing.

To request Minims, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Compared with alternatives such as rose bengal or lissamine green, fluorescein sodium provides rapid staining, strong fluorescence under blue light, and a well‑established safety profile. The addition of lidocaine in Minims offers the advantage of simultaneous anesthesia, reducing the need for a separate anesthetic drop.

Minims should be stored at room temperature, ideally below 25 °C, in its original sealed container. Protect the solution from direct light and moisture to maintain stability. Do not freeze the product, and keep it out of reach of children.

Minims is applied topically to the eye as a sterile drop. The prescriber will instruct the patient on the number of drops, the interval between applications, and any necessary precautions such as removing contact lenses before instillation.

Serious risks, although rare, include allergic reactions that may progress to anaphylaxis, corneal toxicity leading to persistent epithelial defects, and significant elevation of intra‑ocular pressure. Patients should be monitored for signs of severe irritation, swelling, or vision changes and seek immediate medical attention if they occur.

Minims should be avoided in individuals with known hypersensitivity to fluorescein, lidocaine, or any excipients in the formulation. Patients with active ocular infections, severe corneal disease, or uncontrolled intra‑ocular pressure should consult their eye‑care provider before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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