Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited (Fluorescein Sodium)

• Fluorescein Sodium is employed in ophthalmic diagnostics to highlight corneal and tear‑film abnormalities.
• Corneal abrasion: enables visualization of epithelial defects for accurate diagnosis.
• Dry eye assessment: highlights tear‑film breakup patterns to evaluate tear‑film integrity.
• Corneal staining: assists in detecting superficial lesions and ulcerations during slit‑lamp examination.

• Fluorescein Sodium binds to proteins and cellular debris on the ocular surface, forming a fluorescent complex that emits bright green light when illuminated with cobalt blue or ultraviolet wavelengths. This fluorescence accentuates defects, allowing clinicians to visualize corneal epithelial disruptions, tear‑film gaps, and other surface irregularities during slit‑lamp examination.

Fluorescein Sodium may cause transient ocular reactions.

Common Side Effects

• Burning or stinging sensation upon instillation.
• Temporary blurred vision lasting a few minutes.
• Mild conjunctival redness.
• Increased tearing.
• Mild allergic contact dermatitis of the eyelid skin.

Serious or Rare Side Effects

• Severe allergic reaction (anaphylaxis) with swelling or difficulty breathing.
• Persistent corneal staining that interferes with vision.
• Corneal edema or inflammation.
• Intraocular inflammation if the dye enters the anterior chamber.
• Systemic hypersensitivity manifesting as rash or fever.

Proper use of Fluorescein Sodium requires attention to patient history and handling.

• Allergy assessment: verify no known hypersensitivity to fluorescein or sodium salts.
• Pregnancy: use only if clearly needed, as safety data are limited.
• Contact lenses: remove lenses before application to avoid staining and discomfort.
• Concurrent ocular medications: avoid mixing with other eye drops unless directed by a clinician.
• Active eye infection or severe inflammation: postpone use until the condition is stabilized.
• Store at below 25°C: keep in the original container, protect from moisture and light.

Fluorescein Sodium may interact with certain ophthalmic products and systemic agents.

Major Interactions (Avoid)

• Intravenous fluorescein: avoid simultaneous ocular use to prevent cumulative systemic exposure.
• Topical povidone‑iodine: may reduce staining efficacy if applied immediately before fluorescein.

Moderate Interactions (Monitor Closely)

• Contact lens cleaning solutions: may alter staining pattern; ensure lenses are removed and cleaned separately.
• Topical corticosteroids: may mask inflammation, affecting interpretation of staining.
• Antihistamine eye drops: can increase ocular irritation when used together.
• Systemic tetracyclines: may influence tear‑film quality and affect assessment results.
• Other ocular dyes: stagger application times to prevent interference with fluorescence.