Product image of Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited (Fluorescein Sodium) supplied by GNH India

Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited

Active Ingredient:
Fluorescein Sodium
Origin:
EU

Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited (Fluorescein Sodium)

Fluorescein sodium, the active ingredient in Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited, is an ophthalmic diagnostic dye presented as an ophthalmic solution for ocular use. It highlights corneal and conjunctival defects to aid diagnostic examination of the ocular surface.

GNH India supplies Minims Fluoresceine Sodique Bausch + Lomb Ireland Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Fluorescein sodium is used as an ophthalmic diagnostic dye to assess ocular surface integrity.

  • Corneal abrasion: facilitates visualization of epithelial defects for accurate diagnosis.
  • Conjunctival staining: highlights areas of damage or inflammation to guide treatment decisions.
  • Contact lens fitting: reveals tear‑film breakup patterns to optimise lens selection.

How It Works

  • Fluorescein sodium acts as a fluorescent tracer that penetrates damaged epithelial cells and intercellular spaces on the ocular surface. When illuminated with cobalt‑blue light, the dye emits a bright green fluorescence, delineating corneal and conjunctival defects and allowing clinicians to visualise areas of epithelial loss or disruption.

Side Effects

Fluorescein sodium is generally well tolerated, but ocular irritation may occur.

Common Side Effects

  • Mild eye irritation: transient burning or stinging sensation.
  • Temporary blurry vision: resolves as the dye clears.
  • Transient staining of eyelids or lashes.
  • Mild tearing or lacrimation.
  • Slight redness of the conjunctiva.
  • Temporary discomfort during application.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or angioedema.
  • Severe ocular inflammation or uveitis.
  • Corneal edema or swelling.
  • Systemic hypersensitivity: difficulty breathing or anaphylaxis.
  • Persistent staining that does not clear within 24 hours.
  • Vision loss (extremely rare).

Precautions & Warnings

Before using Fluorescein sodium, consider the following safety measures.

  • Allergy assessment: verify no known hypersensitivity to fluorescein or sodium salts.
  • Pregnancy: safety not established; use only if the potential benefit justifies the risk.
  • Contact lens wearers: remove lenses prior to instillation to avoid staining.
  • Concurrent ocular medications: avoid instilling other drops within 5 minutes to prevent dilution or interaction.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Fluorescein sodium may interact with certain ophthalmic agents.

Major Interactions (Avoid)

  • Topical anesthetics: may increase corneal toxicity when combined.
  • Systemic sulfonamides: rare cross‑reactivity leading to hypersensitivity.
  • Other ocular dyes: additive staining can obscure diagnostic interpretation.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: may alter tear film and affect dye distribution.
  • Anti‑inflammatory eye drops: monitor for reduced staining intensity.
  • Preservative‑containing solutions: assess for increased irritation.

Frequently Asked Questions

Minims Fluoresceine Sodique contains fluorescein sodium, an ophthalmic diagnostic dye used to highlight corneal and conjunctival defects. It assists eye care professionals in evaluating the integrity of the ocular surface during examinations such as corneal abrasion assessment, contact lens fitting, and other diagnostic procedures.

Fluorescein sodium penetrates damaged epithelial cells on the eye’s surface. When illuminated with cobalt‑blue light, the dye fluoresces green, outlining areas of loss or disruption. This visual contrast enables clinicians to identify and document lesions, tears, or staining patterns accurately.

The appropriate dose of Minims Fluoresceine Sodique is determined by the prescribing eye care professional. Typically, a single drop is instilled onto the ocular surface, but the exact volume and frequency depend on the specific diagnostic procedure and patient needs.

Safety data for fluorescein sodium in pregnancy and lactation are limited. It is classified as pregnancy category unknown, so it should be used only if the potential benefit justifies any possible risk to the fetus or infant. Consultation with a healthcare provider is essential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details and any necessary import documentation.

Fluorescein sodium is the most widely used ophthalmic diagnostic dye due to its strong fluorescence, safety profile, and ease of use. Alternatives such as lissamine green or rose bengal may be chosen for specific indications, but fluorescein remains the standard for routine corneal and conjunctival staining.

Store the ophthalmic solution at room temperature, preferably below 25 °C, in its original container. Protect it from direct sunlight, excessive heat and moisture. Ensure the cap is tightly closed to maintain sterility and prevent evaporation.

The product is administered as an ophthalmic solution. The prescriber typically instills a single drop onto the conjunctival sac of the eye being examined. After application, the clinician illuminates the eye with cobalt‑blue light to visualise the fluorescence.

Serious risks, although rare, include severe allergic reactions such as angioedema or anaphylaxis, significant ocular inflammation, and corneal edema. Patients should be monitored for any signs of systemic hypersensitivity or worsening ocular symptoms and seek immediate medical attention if they occur.

Individuals with a known hypersensitivity to fluorescein sodium or any component of the formulation should avoid using the product. It is also contraindicated in patients who have experienced severe reactions to other ophthalmic dyes or who have active ocular infections that could be exacerbated by dye application.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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