Product image of Minims Phenylephrine Chlorhydrate Bausch + Lomb Ireland Limited (Phenylephrine Hydrochloride) supplied by GNH India

Minims Phenylephrine Chlorhydrate Bausch + Lomb Ireland Limited

Active Ingredient:
Phenylephrine Hydrochloride
Origin:
EU

Minims Phenylephrine Chlorhydrate Bausch + Lomb Ireland Limited (Phenylephrine Hydrochloride)

Phenylephrine Hydrochloride, the active ingredient in Minims Phenylephrine Chlorhydrate, is an alpha‑adrenergic agonist presented as an ophthalmic preparation for ocular use. It is employed to dilate the pupil during eye examinations and to reduce conjunctival redness.

GNH India supplies Minims Phenylephrine Chlorhydrate as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Phenylephrine Hydrochloride acts on ocular alpha‑1 receptors to produce vasoconstriction and mydriasis, making it useful in several eye‑care situations.

  • Mydriasis for eye examinations: provides rapid pupil dilation to facilitate fundus evaluation.
  • Reduction of ocular redness: constricts conjunctival vessels to lessen visible hyperemia.
  • Pre‑operative ocular decongestion: prepares the eye for surgical procedures by minimizing vascular engorgement.

How It Works

  • Phenylephrine Hydrochloride selectively stimulates alpha‑1 adrenergic receptors on the smooth muscle of ocular blood vessels and the iris dilator muscle. Activation leads to vasoconstriction of conjunctival vessels, decreasing redness, and contraction of the dilator muscle, resulting in pupil dilation (mydriasis). The localized effect limits systemic absorption, focusing action within the eye.

Side Effects

Phenylephrine Hydrochloride may cause ocular and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Burning or stinging sensation upon instillation
  • Transient blurred vision
  • Mild headache
  • Temporary increase in intra‑ocular pressure
  • Mild allergic conjunctivitis
  • Redness that resolves quickly

Serious or Rare Side Effects

  • Acute angle‑closure glaucoma
  • Severe allergic reaction (anaphylaxis)
  • Persistent mydriasis lasting several hours
  • Corneal ulceration or keratitis
  • Vision loss due to ischemic events
  • Systemic hypertension spikes in susceptible individuals

Precautions & Warnings

Before using Phenylephrine Hydrochloride eye drops, consider the following safety measures.

  • Contraindication in narrow‑angle glaucoma: avoid use to prevent acute pressure rise.
  • Caution in patients with uncontrolled hypertension: monitor blood pressure.
  • Avoid in individuals with known hypersensitivity to phenylephrine or formulation excipients.
  • Do not combine with other mydriatic agents unless directed by an eye specialist.
  • Monitor intra‑ocular pressure in patients at risk for glaucoma.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Phenylephrine Hydrochloride can interact with other systemic or ocular agents, influencing its safety profile.

Major Interactions (Avoid)

  • Systemic sympathomimetics (e.g., pseudoephedrine) – additive vasoconstrictive effect.
  • Other topical ocular vasoconstrictors – risk of excessive ischemia.

Moderate Interactions (Monitor Closely)

  • Antihypertensive medications (beta‑blockers, ACE inhibitors) – may blunt systemic blood‑pressure response.
  • Monoamine oxidase inhibitors (MAOIs) – potential for heightened sympathetic activity.
  • Tricyclic antidepressants – possible increase in systemic adrenergic effects.

Frequently Asked Questions

Minims Phenylephrine Chlorhydrate is an ophthalmic preparation that provides pupil dilation (mydriasis) for eye examinations and reduces conjunctival redness by constricting ocular blood vessels. It is commonly used by eye care professionals to improve visibility during diagnostic procedures and to alleviate mild ocular hyperemia.

Phenylephrine hydrochloride acts as a selective alpha‑1 adrenergic receptor agonist. When applied to the eye, it stimulates receptors on the iris dilator muscle, causing the pupil to enlarge, and on conjunctival vessels, leading to vasoconstriction. This dual action results in mydriasis and reduced redness.

The appropriate dose of Minims Phenylephrine Chlorhydrate is determined by the prescribing eye care professional based on the specific clinical need, patient age, and ocular condition. The prescriber will provide exact instructions on the number of drops and frequency of administration.

Safety data for phenylephrine hydrochloride in pregnancy and lactation are limited. Health care providers generally weigh the potential benefits against any possible risks before prescribing. Patients who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Compared with alternatives such as naphazoline or tetrahydrozoline, phenylephrine offers both mydriatic and vasoconstrictive effects, making it useful for diagnostic dilation as well as redness reduction. Its selectivity for alpha‑1 receptors may result in a slightly different side‑effect profile, particularly regarding intra‑ocular pressure changes.

Store the product at room temperature, ideally below 25 °C. Keep the bottle in its original packaging, protect it from direct sunlight, and ensure the cap is tightly closed to prevent contamination. Do not freeze or expose to extreme temperatures.

The medication is administered topically to the eye. The prescriber will instruct the patient to instill the recommended number of drops into the conjunctival sac, typically avoiding contact with the eyelid or eyelashes. Hands should be washed before and after application.

Serious risks include acute angle‑closure glaucoma, severe allergic reactions such as anaphylaxis, and prolonged mydriasis that may impair vision. Patients with narrow‑angle glaucoma or known hypersensitivity should avoid use, and any sudden visual changes should prompt immediate medical attention.

Individuals with a diagnosis of narrow‑angle or acute angle‑closure glaucoma, known hypersensitivity to phenylephrine or any formulation component, and those advised by their ophthalmologist to avoid mydriatics should not use this product. Consultation with a health professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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