Product image of Miprosed (Midazolam) supplied by GNH India

Miprosed

Active Ingredient:
Midazolam
Origin:
EU

Miprosed (Midazolam)

Midazolam, the active ingredient in Miprosed, is a benzodiazepine presented as an oral formulation for oral use. It provides rapid sedation, anxiolysis, anticonvulsant and muscle‑relaxant effects for patients who need short‑term control of anxiety, pre‑operative preparation, procedural sedation, insomnia or seizure management.

GNH India supplies Miprosed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Syri Pharma Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Midazolam is a benzodiazepine that acts on the central nervous system to provide sedation and anxiolysis.

  • Anxiety: reduces acute anxiety symptoms and promotes calmness in short‑term situations.
  • Pre‑operative sedation: facilitates patient relaxation and amnesia before surgical procedures.
  • Procedural sedation: enables safe, controlled sedation during minor diagnostic or therapeutic interventions.
  • Insomnia: induces sleep onset for patients with transient sleep disturbances.
  • Seizure control: aborts acute seizure activity and provides adjunctive anticonvulsant effect.

How It Works

  • Midazolam binds to a specific site on the gamma‑aminobutyric acid type A (GABA‑A) receptor complex, acting as a positive allosteric modulator. This enhances the frequency of chloride channel opening in response to GABA, increasing neuronal hyperpolarisation and producing sedative, anxiolytic, anticonvulsant, muscle‑relaxant and amnestic effects.

Side Effects

Midazolam may cause a range of adverse reactions, from mild to severe, depending on dose, patient factors and concomitant medications.

Common Side Effects

  • Drowsiness
  • Dizziness
  • Impaired coordination
  • Amnesia

Serious or Rare Side Effects

  • Respiratory depression
  • Severe allergic reaction (anaphylaxis)
  • Paradoxical agitation or aggression

Precautions & Warnings

Midazolam requires careful clinical assessment and monitoring to minimise risks.

  • Assess respiratory function: evaluate baseline breathing status before administration.
  • Use caution in the elderly: lower doses may be needed due to increased sensitivity.
  • Avoid abrupt discontinuation: taper gradually to prevent withdrawal seizures.
  • Monitor for dependence: limit duration of use and assess for signs of misuse.
  • Contraindicated in severe obstructive sleep apnea: risk of profound respiratory compromise.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Midazolam interacts with several drug classes that can amplify its sedative properties or alter its plasma concentration.

Major Interactions (Avoid)

  • Opioids: additive respiratory depression and profound sedation.
  • CNS depressants (e.g., barbiturates, alcohol): increased risk of excessive sedation and respiratory compromise.
  • Antifungal azoles (ketoconazole, itraconazole): inhibition of metabolism leading to higher midazolam levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): potential for serotonin syndrome when combined with serotonergic agents.
  • Anticonvulsants (phenytoin, carbamazepine): induction of metabolism may reduce midazolam efficacy.

Frequently Asked Questions

Miprosed contains midazolam, a benzodiazepine used for short‑term relief of anxiety, pre‑operative and procedural sedation, treatment of insomnia, and control of acute seizure activity. It provides rapid onset of sedation and amnesia, making it suitable for hospital and clinical settings where brief, controllable sedation is required.

Midazolam binds to the GABA‑A receptor as a positive allosteric modulator, increasing the frequency of chloride channel opening when GABA binds. This enhances neuronal inhibition, leading to sedation, anxiolysis, muscle relaxation, anticonvulsant activity, and amnesia.

The appropriate dose of Miprosed is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and intended use. Dosage regimens are individualized and should follow local prescribing guidelines and the prescriber’s judgment.

The safety of midazolam in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, and clinicians usually avoid its use unless the potential benefit justifies the potential risk to the fetus or infant. Breastfeeding mothers should discuss alternatives with their healthcare provider.

To request Miprosed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will ask for trade or institutional credentials. The team then replies with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Midazolam has a rapid onset and relatively short duration compared with many other benzodiazepines, making it advantageous for procedural sedation and short‑term anxiolysis. Unlike longer‑acting agents such as diazepam, midazolam allows quicker recovery, but it still shares similar risks of respiratory depression and dependence.

Miprosed should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in areas with high humidity or direct sunlight.

Miprosed is formulated for oral administration. The tablet (or oral solution, if applicable) is swallowed whole with water. The exact route, timing and dosage are determined by the prescriber, who may adjust based on the intended clinical effect and patient response.

The most serious risks include respiratory depression, severe allergic reactions (anaphylaxis), and paradoxical reactions such as agitation or aggression. Patients with compromised breathing, severe sleep apnea, or those taking other central nervous system depressants require close monitoring.

Miprosed is contraindicated in patients with known hypersensitivity to midazolam or other benzodiazepines, those with severe obstructive sleep apnea, and individuals with acute narrow‑angle glaucoma. Caution is also advised for patients with significant hepatic impairment, the elderly, and those taking interacting CNS depressants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.