Product image of Mirabegron Glenmark (Mirabegron) supplied by GNH India

Mirabegron Glenmark

Active Ingredient:
Mirabegron
Origin:
EU

Mirabegron Glenmark (Mirabegron)

Mirabegron, the active ingredient in Mirabegron Glenmark, is a beta-3 adrenergic receptor agonist presented as an oral tablet for oral use. It treats overactive bladder symptoms such as urgency, frequency and urge urinary incontinence in adults.

GNH India supplies Mirabegron Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Mirabegron is indicated for conditions within the overactive bladder disease family.

  • Overactive bladder: reduces urinary urgency and frequency, improving bladder capacity.
  • Urinary urgency: lessens the sudden strong urge to void.
  • Urge urinary incontinence: decreases episodes of involuntary leakage.

How It Works

  • Mirabegron activates β3‑adrenergic receptors located in the detrusor smooth muscle of the bladder. Receptor stimulation leads to relaxation of the bladder wall, which increases functional bladder capacity and reduces involuntary contractions, thereby alleviating symptoms of overactive bladder.

Side Effects

Common Side Effects

  • Hypertension
  • Nasopharyngitis
  • Urinary tract infection
  • Headache
  • Constipation
  • Dry mouth

Serious or Rare Side Effects

  • Urinary retention
  • Tachycardia
  • Angioedema
  • Severe hypertension
  • Allergic reactions (including rash, pruritus)
  • Myocardial infarction

Precautions & Warnings

Precautions should be observed before initiating therapy.

  • Assess cardiovascular status: monitor blood pressure before and during treatment.
  • Review renal function: dose may need adjustment in severe impairment.
  • Avoid use in uncontrolled hypertension: contraindicated.
  • Caution in hepatic impairment: monitor liver enzymes regularly.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Potential drug interactions require careful assessment.

Major Interactions (Avoid)

  • Strong CYP2D6 inhibitors: may increase mirabegron exposure.
  • Antihypertensive agents: additive blood‑pressure‑lowering effect.
  • Norepinephrine reuptake inhibitors: risk of increased hypertension.
  • Diuretics: may reduce mirabegron efficacy.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may diminish therapeutic benefit.
  • Other β3‑adrenergic agonists: potential additive bladder effects.
  • Warfarin: monitor INR as mirabegron can affect metabolism.

Frequently Asked Questions

Mirabegron Glenmark is prescribed to manage symptoms of overactive bladder, including urinary urgency, frequency, and urge urinary incontinence. It helps increase bladder capacity and reduce involuntary contractions, improving daily comfort for patients with these conditions.

The drug activates β3‑adrenergic receptors in the bladder’s detrusor muscle. This activation relaxes the smooth muscle, allowing the bladder to hold a larger volume of urine and decreasing the frequency of unwanted contractions that cause urgency and leakage.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s clinical condition, renal function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Mirabegron in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mirabegron belongs to a different class (β3‑adrenergic agonist) and does not have the anticholinergic side‑effects such as dry mouth or constipation that are common with anticholinergic agents. It may be chosen when patients cannot tolerate anticholinergics or when a different mechanism of action is desired.

Store the tablets at ambient temperature below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and ensure they are out of reach of children.

Mirabegron Glenmark is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed.

Serious risks include significant hypertension, urinary retention, tachycardia, angioedema and rare cardiac events such as myocardial infarction. Patients should be monitored for these conditions, especially if they have pre‑existing cardiovascular disease.

Mirabegron is contraindicated in patients with uncontrolled hypertension and should be used with caution in those with severe renal or hepatic impairment. Individuals who have experienced severe allergic reactions to mirabegron or any of its excipients should also avoid the medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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