Product image of Mirabegron Glenmark (Mirabegron) supplied by GNH India

Mirabegron Glenmark

Active Ingredient:
Mirabegron
Origin:
EU

Mirabegron Glenmark (Mirabegron)

Mirabegron, the active ingredient in Mirabegron Glenmark, is a β3‑adrenergic receptor agonist presented as a tablet for oral use. It treats overactive bladder symptoms such as urgency, frequency and urge incontinence in adults.

GNH India supplies Mirabegron Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Mirabegron is used to manage disorders of bladder storage that involve detrusor overactivity.
  • Overactive bladder: improves bladder capacity and reduces urgency episodes
  • Urinary urgency: lessens the frequency of sudden urges to void
  • Urinary frequency: decreases daytime voiding episodes
  • Urge urinary incontinence: reduces episodes of involuntary leakage

How It Works

  • Mirabegron selectively stimulates β3‑adrenergic receptors located on detrusor smooth muscle. Activation of these receptors triggers a cascade that relaxes the muscle, increasing bladder storage capacity and diminishing involuntary contractions, thereby alleviating urgency, frequency and urge incontinence associated with overactive bladder.

Side Effects

Common Side Effects

  • Hypertension: mild to moderate increase in blood pressure
  • Nasopharyngitis: inflammation of the nasal passages and throat
  • Headache: transient pain in the head region
  • Constipation: reduced bowel motility leading to hard stools

Serious or Rare Side Effects

  • Severe hypertension: marked elevation of blood pressure requiring medical attention
  • Urinary retention: inability to empty the bladder fully
  • Tachycardia: rapid heart rate that may be symptomatic
  • Angioedema: swelling of deep skin layers, potentially airway‑compromising
  • Anaphylaxis: severe allergic reaction with systemic involvement

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Monitor blood pressure: check regularly as Mirabegron may raise systolic values
  • Assess renal function: dose adjustment may be needed in severe impairment
  • Review cardiovascular status: use caution in patients with arrhythmias
  • Avoid in uncontrolled hypertension: contraindicated when blood pressure is not controlled
  • Store at ambient temperature: keep below 25°C, in the original pack, and protect from moisture

Avoid Interactions

Mirabegron can affect the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Strong CYP2D6 inhibitors (e.g., paroxetine): may increase Mirabegron exposure
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can raise plasma levels
  • Antihypertensive agents: may reduce their efficacy
  • Monoamine oxidase inhibitors: risk of hypertensive crisis

Moderate Interactions (Monitor Closely)

  • CYP2D6 substrates (e.g., metoprolol): monitor for increased effects
  • CYP3A4 substrates (e.g., midazolam): observe for enhanced sedation
  • Diuretics: watch electrolyte balance and volume status

Frequently Asked Questions

Mirabegron Glenmark is indicated for the treatment of overactive bladder symptoms, including urinary urgency, increased daytime frequency, and urge urinary incontinence. It helps patients regain better bladder control by reducing involuntary detrusor contractions.

Mirabegron works by selectively activating β3‑adrenergic receptors on the bladder’s detrusor muscle. This activation relaxes the smooth muscle, expands bladder capacity, and diminishes spontaneous contractions that cause urgency and incontinence.

The dosage of Mirabegron is individualized by the prescribing healthcare professional based on the patient’s clinical condition, renal function, and concomitant therapies. The prescriber determines the appropriate strength and titration schedule.

Mirabegron is classified as Pregnancy Category B, indicating that animal studies have not shown fetal risk, but adequate human data are lacking. It should be used during pregnancy only if the potential benefit justifies the risk. Limited data are available for breastfeeding; a risk‑benefit assessment is recommended.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and the necessary import documentation.

The primary alternative class for overactive bladder are antimuscarinic drugs, which block muscarinic receptors to reduce bladder contractions. Mirabegron, as a β3‑agonist, offers a different mechanism and is often better tolerated regarding dry mouth and constipation, but may raise blood pressure, a consideration absent with many antimuscarinics.

Mirabegron tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister or container, protect from moisture and direct sunlight, and ensure they are out of reach of children.

Mirabegron is taken orally as a tablet, with or without food, according to the prescriber’s instructions. Swallow the tablet whole with water; do not crush, split, or chew unless specifically advised.

Serious adverse events include severe hypertension, urinary retention, tachycardia, angioedema and rare cases of anaphylaxis. Patients should seek immediate medical attention if they experience a sudden rise in blood pressure, inability to urinate, rapid heartbeat, swelling of the face or throat, or signs of an allergic reaction.

Mirabegron is contraindicated in patients with uncontrolled hypertension, severe hepatic impairment, or known hypersensitivity to the drug or any of its excipients. Caution is also advised for individuals with significant cardiovascular disease or those taking strong CYP2D6 or CYP3A4 inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.