Product image of Mirabegron Ratiopharm (Mirabegron) supplied by GNH India

Mirabegron Ratiopharm

Active Ingredient:
Mirabegron
Origin:
EU

Mirabegron Ratiopharm (Mirabegron)

Mirabegron, the active ingredient in Mirabegron Ratiopharm, is a Beta‑3 adrenergic receptor agonist presented as an oral tablet for oral use. It is indicated for the treatment of overactive bladder symptoms such as urgency, frequency and urge urinary incontinence in adults.
GNH India supplies Mirabegron Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mirabegron acts on the lower urinary tract to improve storage symptoms associated with overactive bladder.

  • Overactive bladder: reduces urgency episodes and increases functional bladder capacity.
  • Urinary urgency: lessens the sudden need to void.
  • Urinary frequency: decreases the number of daytime voids.
  • Urge urinary incontinence: helps prevent involuntary leakage.

How It Works

  • Mirabegron selectively stimulates β3‑adrenergic receptors in the detrusor smooth muscle of the bladder, leading to relaxation of the muscle during the storage phase. This relaxation increases bladder capacity and reduces involuntary contractions, thereby improving urinary storage symptoms without affecting the contractile function needed for voiding.

Side Effects

Adverse reactions may occur with mirabegron therapy.

Common Side Effects

  • Headache
  • Hypertension
  • Nasopharyngitis
  • Urinary retention
  • Constipation
  • Dry mouth

Serious or Rare Side Effects

  • Severe hypertension or hypertensive crisis
  • Acute urinary retention requiring catheterisation
  • Angioedema
  • Myocardial infarction or other serious cardiac events
  • Severe liver injury or hepatitis

Precautions & Warnings

Before initiating mirabegron, several safety considerations should be reviewed.

  • Assess cardiovascular status: monitor blood pressure and heart rate prior to and during treatment.
  • Evaluate renal function: dose adjustment may be required in severe impairment.
  • Review concomitant medications: avoid strong CYP2D6 inhibitors where possible.
  • Monitor for urinary retention: especially in patients with bladder outlet obstruction.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Mirabegron may interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP2D6 inhibitors (e.g., fluoxetine, quinidine): may increase mirabegron exposure.
  • Anticholinergic agents: may diminish the therapeutic effect on bladder storage.
  • Norepinephrine reuptake inhibitors: can raise blood pressure risk.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect blood pressure control when combined.
  • Beta‑blockers: may blunt mirabegron's effect on detrusor relaxation.

Frequently Asked Questions

Mirabegron Ratiopharm is prescribed to manage symptoms of overactive bladder, including urinary urgency, increased frequency of daytime voiding, and urge urinary incontinence. It helps improve bladder storage capacity and reduces the occurrence of involuntary bladder contractions.

Mirabegron selectively activates β3‑adrenergic receptors in the detrusor muscle of the bladder. This activation relaxes the muscle during the filling phase, increasing bladder capacity and decreasing involuntary contractions that cause urgency and leakage.

The specific dose of mirabegron is determined by the prescribing clinician based on the patient’s medical condition, renal function, and concomitant medications. The prescriber will select the appropriate strength and dosing schedule for each individual.

Safety data for mirabegron in pregnancy and lactation are limited, and the medication is generally not recommended unless the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mirabegron offers a non‑anticholinergic option, which can be advantageous for patients who experience dry mouth, constipation or cognitive effects with antimuscarinics. Both classes improve bladder storage symptoms, but mirabegron may be preferred when anticholinergic side effects are a concern or when combination therapy is needed.

Store the tablets at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from excess moisture and direct sunlight. Do not refrigerate or freeze the product, and keep it out of reach of children.

Mirabegron Ratiopharm is taken orally, usually once daily, with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole with a glass of water and not chewed or crushed.

Serious risks include significant hypertension, acute urinary retention that may require catheterisation, angioedema, and rare cardiac events such as myocardial infarction. Patients should promptly report severe headache, chest pain, sudden swelling of the face or throat, or inability to urinate.

Mirabegron is contraindicated in patients with uncontrolled hypertension, severe hepatic impairment, or known hypersensitivity to mirabegron or any of its excipients. Caution is also advised for individuals with bladder outlet obstruction or those taking strong CYP2D6 inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.