Product image of Mirabegron Stada (Mirabegron) supplied by GNH India

Mirabegron Stada

Active Ingredient:
Mirabegron
Origin:
EU

Mirabegron Stada (Mirabegron)

Mirabegron, the active ingredient in Mirabegron Stada, is a Beta-3 adrenergic receptor agonist presented as an oral formulation for oral use. It relaxes detrusor smooth muscle, increasing bladder capacity and reducing involuntary contractions, and is indicated for the management of overactive bladder symptoms such as urgency, frequency and urge incontinence in adult patients.

GNH India supplies Mirabegron Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory support for global markets.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Mirabegron is used to treat conditions related to overactive bladder by targeting the beta‑3 adrenergic pathway.

  • Overactive bladder: reduces urgency and frequency by increasing bladder capacity.
  • Urinary urgency: diminishes the sudden need to void.
  • Urinary frequency: lowers the number of daily voids.
  • Urge urinary incontinence: decreases episodes of involuntary leakage.

How It Works

  • Mirabegron selectively activates beta‑3 adrenergic receptors located on detrusor smooth muscle cells in the urinary bladder. This activation triggers a cascade that relaxes the muscle, thereby increasing bladder storage capacity and reducing involuntary contractions that cause urgency and incontinence.

Side Effects

Adverse reactions reported with Mirabegron Stada vary in frequency and severity.

Common Side Effects

  • Hypertension: elevated blood pressure readings.
  • Headache: mild to moderate intensity.
  • Nasopharyngitis: symptoms of common cold.
  • Dry mouth: reduced salivation.

Serious or Rare Side Effects

  • Urinary retention: difficulty emptying the bladder.
  • Tachycardia: increased heart rate.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal impairment: assess renal function and adjust therapy if needed.
  • Hepatic impairment: evaluate liver function and monitor for adverse effects.
  • Cardiovascular disease: monitor blood pressure and heart rate regularly.
  • Concomitant antihypertensives: watch for additive blood pressure effects.
  • Drug interactions: review patient medication list for potential interactions.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Mirabegron may interact with several drug classes; monitor patients accordingly.

Major Interactions (Avoid)

  • Strong CYP2D6 inhibitors (e.g., paroxetine, fluoxetine): may increase Mirabegron plasma levels.
  • Antihypertensive agents (e.g., beta‑blockers): risk of additive blood pressure reduction.

Moderate Interactions (Monitor Closely)

  • CYP3A4 substrates (e.g., midazolam): possible modest increase in exposure.
  • Diuretics: may affect electrolyte balance and blood pressure.
  • Anticholinergic drugs: monitor for additive urinary effects.

Frequently Asked Questions

Mirabegron Stada is prescribed to manage symptoms of overactive bladder, including urinary urgency, increased frequency of voiding, and urge urinary incontinence. By improving bladder storage capacity, it helps patients achieve better control over urinary habits and reduces the impact of these symptoms on daily life.

Mirabegron works by selectively stimulating beta‑3 adrenergic receptors in the detrusor smooth muscle of the bladder. This activation relaxes the muscle, allowing the bladder to hold a larger volume of urine and decreasing involuntary contractions that cause urgency and leakage.

The dose of Mirabegron Stada is determined by the prescribing healthcare professional based on the individual’s condition, renal function, and response to therapy. Common practice starts with a low dose that may be titrated, but exact dosing should always follow the prescriber’s instructions.

Safety data for Mirabegron Stada in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To order Mirabegron Stada, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mirabegron offers a non‑anticholinergic alternative for overactive bladder. Unlike antimuscarinics, it does not commonly cause dry mouth or constipation, but it may raise blood pressure in some patients. Choice of therapy depends on individual tolerability, comorbidities and physician assessment.

Mirabegron Stada should be stored at ambient temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Mirabegron Stada is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious risks include significant hypertension, urinary retention that may require catheterisation, and rare severe allergic reactions such as anaphylaxis. Patients should be monitored for elevated blood pressure, difficulty emptying the bladder, and any signs of hypersensitivity.

Mirabegron Stada is contraindicated in patients with uncontrolled hypertension, severe urinary retention, or known hypersensitivity to Mirabegron or any excipients. Caution is also advised for individuals with significant renal or hepatic impairment, and it should be avoided in those taking strong CYP2D6 inhibitors without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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