Product image of Mirabella (Ethinylestradiol, Levonorgestrel | Lactose) supplied by GNH India

Mirabella

Active Ingredient:
Ethinylestradiol, Levonorgestrel | Lactose
Origin:
EU

Mirabella (Ethinylestradiol, Levonorgestrel | Lactose)

Ethinylestradiol and Levonorgestrel, the active ingredients in Mirabella, are a combined oral contraceptive presented as tablets for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus and the endometrial lining.
GNH India supplies Mirabella as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Exeltis Healthcare S.L

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Indications & Clinical Uses

  • Mirabella, a combined oral contraceptive, is used to prevent pregnancy by influencing the hormonal regulation of the menstrual cycle.
  • Contraception (prevention of pregnancy): provides reliable, reversible birth control.
  • Menstrual cycle regulation: helps achieve more predictable bleeding patterns and may reduce dysmenorrhea.
  • Acne improvement: can lessen acne associated with androgen excess.
  • Endometrial protection: reduces the risk of endometrial hyperplasia in women requiring estrogen therapy.

How It Works

  • Mirabella contains ethinylestradiol, a synthetic estrogen, and levonorgestrel, a synthetic progestogen. The estrogen component suppresses follicle‑stimulating hormone, while the progestogen inhibits luteinizing hormone surge, together preventing ovulation. Additionally, levonorgestrel thickens cervical mucus and alters the endometrial lining, creating an environment unfavorable for fertilization and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: occasional mild to moderate pain.
  • Spotting or breakthrough bleeding: irregular light bleeding.
  • Mood changes: fluctuations in emotional state.
  • Weight gain: slight increase in body weight.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Arterial thrombosis: clot formation in arteries, potentially causing stroke.
  • Hypertension: elevated blood pressure.
  • Liver dysfunction: abnormal liver enzyme levels.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Visual disturbances: sudden vision changes or loss.

Precautions & Warnings

Before using Mirabella, consider the following precautions:

  • Pregnancy: contraindicated in known or suspected pregnancy.
  • Smoking: avoid if over 35 years and a regular smoker.
  • Thromboembolic history: not for patients with past blood clots.
  • Liver disease: contraindicated in active liver disease.
  • Hypertension: monitor blood pressure regularly.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Mirabella may interact with several medicines. Review the following categories:

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): reduce contraceptive effectiveness.
  • Rifampin and other rifamycins: decrease hormone levels.
  • St. John's Wort: may lower contraceptive efficacy.

Moderate Interactions (Monitor Closely)

  • Antifungals (e.g., ketoconazole): may increase hormone concentrations.
  • Certain antidepressants (SSRIs): can enhance bleeding risk.
  • Antihypertensives (e.g., ACE inhibitors): may augment blood‑pressure‑lowering effect.

Frequently Asked Questions

Mirabella is a prescription combined oral contraceptive used to prevent pregnancy in women of reproductive age. It works by inhibiting ovulation and altering cervical mucus and the endometrial lining, providing reliable, reversible birth control.

Ethinylestradiol, a synthetic estrogen, suppresses follicle‑stimulating hormone, while levonorgestrel, a synthetic progestogen, blocks the luteinizing hormone surge, preventing ovulation. Levonorgestrel also thickens cervical mucus and changes the endometrial lining, reducing the chance of fertilization and implantation.

The dosing regimen for Mirabella is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and any missed‑dose instructions should follow the prescriber’s guidance.

Mirabella is contraindicated during pregnancy and should not be started if a woman is pregnant. While limited data exist for breastfeeding, most guidelines advise caution; women should discuss risks and benefits with their healthcare provider before using hormonal contraception while nursing.

To order Mirabella, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mirabella contains the widely used dose combination of ethinylestradiol and levonorgestrel, offering efficacy comparable to other combined oral contraceptives. Its safety profile and side‑effect spectrum are similar to alternative estrogen‑progestin pills, with differences mainly in individual tolerability and specific hormone doses.

Mirabella tablets should be stored at ambient temperature, below 25 °C, in the original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use if the packaging is damaged.

Mirabella is taken orally, usually one tablet each day, preferably at the same time each day. It is part of a 21‑day active tablet regimen followed by a hormone‑free interval, but patients should follow the specific instructions provided by their prescriber.

Serious risks include venous thromboembolism, arterial thrombosis, hypertension, and severe allergic reactions. Women with a history of blood clots, smoking over age 35, uncontrolled hypertension, or liver disease should discuss these risks with their healthcare provider before starting Mirabella.

Mirabella should not be used by women who are pregnant, have a known or suspected pregnancy, have a history of thromboembolic disorders, active liver disease, uncontrolled hypertension, breast cancer, or who are over 35 and smoke regularly. Contraindications must be evaluated by a qualified prescriber.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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