Product image of Miralgin (Paracetamol, Caffeine) supplied by GNH India

Miralgin

Active Ingredient:
Paracetamol, Caffeine
Origin:
EU

Miralgin (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Miralgin, is an analgesic presented as an oral tablet for oral use. Combined with caffeine, it helps relieve headache, migraine, fever and mild to moderate pain in adults and adolescents. It belongs to the analgesic and antipyretic class and is available over the counter across the European Union.

GNH India supplies Miralgin as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU quality standards and providing the product to hospitals, pharmacies and clinics worldwide through regulated distribution channels.

Manufacturer / TM Owner

Pannonpharma Kft.

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Indications & Clinical Uses

Miralgin, containing paracetamol and caffeine, is used to manage pain and fever through inhibition of prostaglandin synthesis and central nervous system stimulation.

  • Headache: reduces intensity and duration of tension‑type and mild migraine headaches.
  • Migraine: provides adjunctive relief when combined with caffeine for acute migraine attacks.
  • Fever: lowers elevated body temperature in febrile conditions.
  • Pain: alleviates mild to moderate musculoskeletal, dental and postoperative pain.

How It Works

  • Paracetamol acts primarily by inhibiting cyclooxygenase enzymes in the central nervous system, decreasing prostaglandin synthesis and thereby reducing pain and fever. Caffeine antagonizes adenosine receptors, leading to increased neuronal firing and enhanced analgesic effect of paracetamol, while also providing mild central stimulation.

Side Effects

Common Side Effects

  • Nausea: mild gastrointestinal discomfort.
  • Stomach upset: occasional dyspepsia or abdominal pain.
  • Insomnia: difficulty falling or staying asleep.
  • Increased heart rate: mild tachycardia.
  • Restlessness: feeling of jitteriness.
  • Headache: paradoxical headache in some users.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Liver toxicity: elevated transaminases or hepatic failure with overdose.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Blood disorders: thrombocytopenia or neutropenia.
  • Cardiovascular events: hypertension or arrhythmia in susceptible individuals.

Precautions & Warnings

Before using Miralgin, consider the following precautions:

  • Assess liver function: avoid or adjust dose in severe hepatic impairment.
  • Limit alcohol intake: concurrent alcohol can increase hepatotoxic risk.
  • Use lowest effective dose: minimize exposure while achieving symptom control.
  • Avoid in children under 12 years: unless directed by a healthcare professional.
  • Consult healthcare professional in pregnancy: safety not fully established.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Miralgin may interact with other medicines as follows:

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Carbamazepine: reduced analgesic efficacy of paracetamol.
  • Lithium: potential for increased lithium toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: enhanced hepatotoxicity risk.
  • Other CNS stimulants (e.g., pseudoephedrine): increased stimulant side effects.
  • Antiepileptic drugs (e.g., phenytoin): altered metabolism of caffeine.

Frequently Asked Questions

Miralgin is an oral tablet that combines paracetamol and caffeine to provide relief from headache, migraine, fever and mild to moderate pain such as musculoskeletal or dental discomfort. It is commonly used as an over‑the‑counter option for adults and adolescents.

Paracetamol reduces pain and fever by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers prostaglandin production. This action diminishes the perception of pain and helps reset the body’s temperature set‑point during fever.

The appropriate dose of Miralgin is determined by a prescriber or according to the product label. Dosage depends on factors such as age, weight, severity of symptoms and any concurrent medical conditions, and should not exceed the recommended maximum for paracetamol.

Safety of Miralgin in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult a healthcare professional before using the product to weigh potential benefits against risks.

To order Miralgin, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with plain paracetamol, Miralgin adds caffeine, which can enhance analgesic efficacy and reduce the need for higher paracetamol doses. Unlike non‑steroidal anti‑inflammatory drugs (NSAIDs), it does not have significant anti‑platelet or gastric irritation effects, making it a suitable alternative for patients who cannot tolerate NSAIDs.

Miralgin should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Miralgin is taken orally with a glass of water. It can be taken with or without food, but if gastrointestinal upset occurs, it may be helpful to take the tablet with a small amount of food. Follow the dosing instructions provided by a healthcare professional or the product label.

The most serious risks include severe allergic reactions such as anaphylaxis, rare but serious skin conditions like Stevens‑Johnson syndrome, and liver injury especially when taken in excess or combined with alcohol. Immediate medical attention is required if any signs of these reactions appear.

Individuals with known hypersensitivity to paracetamol, caffeine or any excipients in the tablet should avoid Miralgin. It is also contraindicated in patients with severe liver disease, uncontrolled hypertension, or those taking medications that have major interactions listed above without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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