Product image of Mirspan (Dry Extract Of Melissa Leaf (4-6:1), Extraction Agent: Methanol 30% (V/V), Valerian Root Dry Extract) supplied by GNH India

Mirspan

Active Ingredient:
Dry Extract Of Melissa Leaf (4-6:1), Extraction Agent: Methanol 30% (V/V), Valerian Root Dry Extract
Origin:
EU

Mirspan (Dry Extract Of Melissa Leaf (4-6:1), Extraction Agent: Methanol 30% (V/V), Valerian Root Dry Extract)

Melissa leaf dry extract, the active ingredient in Mirspan, is a herbal supplement presented as a dry extract for oral use. It is combined with Valerian root dry extract and is marketed for mild anxiety, sleep support and stress‑related tension in adults.
GNH India supplies Mirspan as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Apomedica Pharmazeutische Produkte Gmbh

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Indications & Clinical Uses

Mirspan is an herbal supplement that acts on the central nervous system to promote relaxation and sleep quality.

  • Mild anxiety: may help reduce feelings of nervousness and promote calmness.
  • Insomnia: may support the onset of sleep and improve sleep continuity.
  • Stress‑related tension: may aid in relaxation during periods of mental or emotional stress.

How It Works

  • Melissa leaf contains rosmarinic acid, flavonoids and essential oils that exhibit mild GABA‑ergic activity, while Valerian root provides valerenic acids that modulate GABA‑A receptors. Together they enhance inhibitory neurotransmission, producing calming and sedative effects without directly binding to opioid or adrenergic receptors.

Side Effects

Common Side Effects

  • Headache: mild, transient discomfort.
  • Gastrointestinal upset: occasional nausea or stomach discomfort.
  • Dizziness: light‑headed sensation, usually resolves quickly.
  • Dry mouth: reduced salivation during use.
  • Fatigue: mild tiredness, especially when taken at night.
  • Mild skin irritation: rare, localized rash.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Liver enzyme elevation: abnormal liver function tests in susceptible individuals.
  • Severe drowsiness: excessive sedation interfering with daily activities.
  • Hallucinations: extremely rare neuropsychiatric events.
  • Respiratory depression: profound sedation when combined with other CNS depressants.
  • Anaphylaxis: life‑threatening allergic response requiring immediate medical attention.

Precautions & Warnings

Precautions should be observed when using Mirspan, especially in special populations and in combination with other agents.

  • Pregnancy: safety not established; avoid unless advised by a healthcare professional.
  • Breastfeeding: use with caution; limited data on infant exposure.
  • Concurrent CNS depressants: may enhance sedative effects; monitor for excessive drowsiness.
  • Liver disease: consider reduced dosage or close monitoring.
  • Alcohol consumption: avoid or limit to prevent additive sedation.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Potential drug interactions may modify the safety profile of Mirspan.

Major Interactions (Avoid)

  • Benzodiazepines: additive central nervous system depression.
  • Barbiturates: increased sedation and respiratory depression risk.
  • Alcohol: synergistic sedative effect, may impair coordination.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): possible enhanced serotonergic activity.
  • Antihistamines: additive drowsiness.
  • Anticoagulants (warfarin, DOACs): potential for increased bleeding tendency.

Frequently Asked Questions

Mirspan is an oral herbal supplement that combines Melissa leaf dry extract and Valerian root dry extract. It is traditionally used to support mild anxiety, promote sleep onset, and help relieve stress‑related tension in adults.

Melissa leaf contains rosmarinic acid and flavonoids that modestly enhance GABA‑ergic neurotransmission, producing calming effects. When combined with Valerian root, which modulates GABA‑A receptors, the formulation may help reduce nervousness and support sleep without strong sedation.

The appropriate dose of Mirspan is determined by the prescribing healthcare professional based on individual needs, age, and clinical condition. Patients should follow the prescriber’s instructions and the product label.

Safety data for Mirspan in pregnancy and lactation are limited. It is generally advised to avoid use during pregnancy and to exercise caution while breastfeeding unless a qualified health professional determines that the potential benefits outweigh any possible risks.

To order Mirspan, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑herb products, Mirspan combines two well‑studied botanicals—Melissa leaf and Valerian root—offering a broader spectrum of mild anxiolytic and sedative actions. This dual‑extract approach may provide more balanced support for both anxiety and sleep than products containing only one of the ingredients.

Mirspan should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and extreme heat to maintain product stability.

Mirspan is taken orally, typically with water. The exact administration schedule, such as timing relative to meals or bedtime, should follow the prescribing clinician’s guidance and the instructions provided on the product label.

Serious risks, though rare, include allergic reactions that may manifest as rash, swelling, or breathing difficulty, and severe drowsiness that could impair daily activities. Users should seek immediate medical attention if they experience any signs of anaphylaxis or unexpected profound sedation.

Individuals with known hypersensitivity to Melissa leaf, Valerian root, or any formulation components should avoid Mirspan. It is also contraindicated in patients taking strong central nervous system depressants, such as benzodiazepines or barbiturates, without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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