Product image of Mirtamor (Mirtazapine) supplied by GNH India

Mirtamor

Active Ingredient:
Mirtazapine
Origin:
EU

Mirtamor (Mirtazapine)

Mirtazapine, the active ingredient in Mirtamor, is a NaSSA (noradrenergic and specific serotonergic antidepressant) presented as an oral tablet for oral use. It is prescribed for the treatment of major depressive disorder in adult patients, helping to improve mood, sleep, and appetite.

GNH India supplies Mirtamor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution. Our network ensures timely delivery and regulatory compliance across multiple regions.

Manufacturer / TM Owner

Innovis Pharma

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Indications & Clinical Uses

Mirtazapine is indicated for depressive disorders and works by modulating noradrenergic and serotonergic pathways.

  • Major depressive disorder: reduces depressive symptoms and improves overall mood.
  • Depression in adults: enhances sleep quality and appetite, supporting functional recovery.
  • Geriatric depression: offers a favorable tolerability profile for elderly patients.

How It Works

  • Mirtazapine acts as an antagonist at central presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine. It also blocks postsynaptic 5‑HT₂ and 5‑HT₃ receptors, enhancing serotonergic transmission while reducing associated side effects. The combined effect raises both norepinephrine and serotonin activity in key brain regions involved in mood regulation. These actions result in a net antidepressant effect that can improve depressive symptoms and sleep patterns.

Side Effects

Mirtazapine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Sedation or drowsiness
  • Increased appetite and weight gain
  • Dry mouth

Serious or Rare Side Effects

  • Agranulocytosis or severe neutropenia
  • Suicidal thoughts or behavior, especially early in treatment
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

When prescribing Mirtazapine, several safety considerations are recommended.

  • Assess suicidality: monitor patients for worsening depression or suicidal ideation, especially during initial weeks.
  • Monitor weight: track changes in appetite and body weight regularly.
  • Caution in hepatic impairment: adjust use in patients with liver dysfunction.
  • Avoid abrupt discontinuation: taper dose under medical supervision to reduce withdrawal symptoms.
  • Use cautiously in elderly: increased risk of sedation and falls.
  • Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Mirtazapine can interact with several drug classes; awareness of the interaction level helps guide clinical decisions.

Major Interactions (Avoid)

  • MAO inhibitors: concurrent use may cause hypertensive crisis.
  • Strong CYP2D6 inhibitors: may increase mirtazapine plasma levels, raising toxicity risk.
  • CNS depressants (e.g., benzodiazepines, opioids): additive sedation and respiratory depression.

Moderate Interactions (Monitor Closely)

  • SSRIs or SNRIs: risk of serotonin syndrome, monitor for symptoms.
  • Antihistamines: may enhance sedative effects.
  • Alcohol: can increase CNS depression and impair coordination.

Frequently Asked Questions

Mirtamor contains the active ingredient mirtazapine, which is prescribed for the treatment of major depressive disorder in adult patients. It helps alleviate depressive symptoms, improve mood, and can also aid sleep and appetite regulation.

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases norepinephrine release, and by antagonising postsynaptic 5‑HT₂ and 5‑HT₃ receptors. This dual action raises both norepinephrine and serotonin levels in brain areas that regulate mood.

The dose of Mirtamor is individualized. A qualified prescriber determines the starting dose and any titration based on the patient’s clinical response, tolerability, and overall health status. Dosage adjustments are made under medical supervision.

Safety of mirtazapine during pregnancy or lactation has not been fully established. It should only be used when the potential benefit outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To order Mirtamor, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with typical SSRIs such as sertraline, mirtazapine has a stronger sedative effect and often increases appetite and weight. It may be preferred when insomnia or loss of appetite are prominent, while SSRIs are generally less sedating and have a different side‑effect profile.

Mirtamor tablets should be stored below 25 °C in their original packaging, protected from moisture and direct light. Keep the product out of reach of children and do not use if the packaging is damaged.

Mirtamor is taken orally as a tablet. It is usually swallowed whole with water, preferably once daily in the evening or at bedtime, unless otherwise directed by a prescriber.

Serious risks include agranulocytosis or severe neutropenia, emergence or worsening of suicidal thoughts especially early in therapy, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should be monitored closely for these events.

Mirtamor should not be used by individuals with known hypersensitivity to mirtazapine, those currently taking monoamine oxidase inhibitors, or patients with severe hepatic impairment. Contraindications are determined by the prescribing clinician based on the patient’s medical history.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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