Product image of Mirtazapin Biomo (Mirtazapine) supplied by GNH India

Mirtazapin Biomo

Active Ingredient:
Mirtazapine
Origin:
EU

Mirtazapin Biomo (Mirtazapine)

Mirtazapine, the active ingredient in Mirtazapin Biomo, is a noradrenergic and specific serotonergic antidepressant (NaSSA) presented as an oral formulation for oral use. It is prescribed for the treatment of major depressive disorder in adult patients and conforms to European Union pharmaceutical standards for prescription medicines.

GNH India supplies Mirtazapin Biomo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing, regulatory documentation and logistics support for global healthcare providers. The company adheres to WHO‑GMP guidelines and offers flexible order volumes.

Manufacturer / TM Owner

Biomo Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mirtazapine, marketed as Mirtazapin Biomo, is indicated for depressive disorders that involve serotonergic and noradrenergic dysregulation.

  • Major depressive disorder: alleviates depressive symptoms and improves mood in adult patients.
  • Depression with insomnia: reduces nighttime awakenings and promotes restorative sleep.
  • Depression with anxiety: helps decrease anxiety symptoms alongside mood improvement.
  • Treatment‑resistant depression (adjunct): may be added when first‑line agents are insufficient.
  • Depressive episodes in bipolar disorder (adjunct): used under specialist supervision when needed.

How It Works

  • Mirtazapine acts as an antagonist at central presynaptic α2‑adrenergic receptors, which disinhibits norepinephrine release, and blocks postsynaptic 5‑HT2, 5‑HT3 and histamine H1 receptors. This combined activity enhances noradrenergic and serotonergic neurotransmission while producing sedative effects, contributing to its antidepressant action.

Side Effects

Mirtazapine may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Sedation or somnolence
  • Increased appetite leading to weight gain
  • Dry mouth
  • Constipation
  • Dizziness
  • Orthostatic hypotension

Serious or Rare Side Effects

  • Agranulocytosis or severe neutropenia
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal ideation or worsening depression
  • Severe hypotension or syncope
  • Hepatic dysfunction
  • Seizures (rare)

Precautions & Warnings

When prescribing Mirtazapine, clinicians should consider several safety measures.

  • Hepatic function: assess liver status before initiating therapy.
  • Mood monitoring: watch for worsening depression or emergent suicidal thoughts.
  • Elderly patients: use caution due to increased risk of sedation and falls.
  • Discontinuation: avoid abrupt cessation to reduce withdrawal phenomena.
  • Concomitant CNS depressants: evaluate additive sedative effects.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Mirtazapine can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome.
  • Other serotonergic antidepressants (e.g., SSRIs, SNRIs): may increase serotonin toxicity.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole): can raise mirtazapine plasma levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: enhances central nervous system depression.
  • Antihistamines: additive sedation.
  • CNS depressants (benzodiazepines, opioids): increased drowsiness.
  • CYP3A4 inducers (e.g., carbamazepine): may reduce efficacy.
  • Warfarin: monitor INR for potential anticoagulant effect changes.

Frequently Asked Questions

Mirtazapin Biomo contains the active ingredient mirtazapine and is used as a prescription antidepressant for the treatment of major depressive disorder in adult patients. It may also be considered for depressive symptoms accompanied by insomnia or anxiety when clinically appropriate.

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine, and by antagonising postsynaptic 5‑HT2, 5‑HT3 and histamine H1 receptors. This combined action enhances serotonergic and noradrenergic neurotransmission while producing a calming, sedative effect.

The dosage of Mirtazapin Biomo is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. Only a qualified healthcare professional should set the dose and any titration schedule.

Safety data for mirtazapine in pregnancy and lactation are limited. The prescribing physician must weigh potential benefits against possible risks to the fetus or infant and follow local regulatory guidance before use in these populations.

To request Mirtazapin Biomo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Mirtazapin Biomo (mirtazapine) belongs to the NaSSA class, differing from SSRIs and SNRIs by its dual antagonism of α2‑adrenergic and specific serotonin receptors. This profile often results in stronger sedative and appetite‑stimulating effects, which can be advantageous for patients with insomnia or weight loss, but may be less suitable for those who need to avoid sedation.

Mirtazapin Biomo should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date.

Mirtazapin Biomo is taken orally, usually once daily in the evening to take advantage of its sedative properties. The tablet should be swallowed whole with water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include the potential for agranulocytosis, severe neutropenia, hepatic dysfunction, and rare cases of Stevens‑Johnson syndrome. Additionally, worsening depression or emergence of suicidal thoughts may occur, especially early in treatment, and require immediate medical attention.

Mirtazapin Biomo is contraindicated in patients with known hypersensitivity to mirtazapine or any of its excipients, and in those currently receiving monoamine oxidase inhibitors (MAOIs). Caution is also advised for individuals with severe hepatic impairment, uncontrolled hypertension, or a history of seizures.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.