Mirtazapina Aurobindo (Mirtazapine)

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine and serotonin. It also antagonises postsynaptic 5‑HT2 and 5‑HT3 receptors and strongly blocks H1 histamine receptors, producing antidepressant, anxiolytic and sedative effects.

The appropriate dose of Mirtazapina Aurobindo is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and tolerability. Dosage may be started low and adjusted gradually; patients should follow the specific instructions provided by their healthcare professional.

Safety data for mirtazapine during pregnancy and lactation are limited, and the drug is classified as having an unknown pregnancy category. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Mirtazapine belongs to the NaSSA class, whereas many other antidepressants are selective serotonin reuptake inhibitors (SSRIs). Compared with SSRIs, mirtazapine often produces stronger sedation and appetite stimulation, which can be advantageous for patients with insomnia or weight loss, but may be less suitable for those concerned about weight gain.

Mirtazapina Aurobindo tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture, direct sunlight and excessive heat. Keep the container tightly closed and out of reach of children.

The medication is taken orally, usually once daily in the evening due to its sedative properties. Tablets should be swallowed whole with a glass of water and may be taken with or without food, following the dosing schedule prescribed by the treating clinician.

Serious adverse effects include agranulocytosis or severe neutropenia, Stevens‑Johnson syndrome or toxic epidermal necrolysis, and the emergence or worsening of suicidal thoughts, particularly during the initial weeks of therapy. Patients should seek immediate medical attention if they notice signs of infection, severe skin reactions, or mood changes.

Mirtazapina Aurobindo is contraindicated in patients with known hypersensitivity to mirtazapine or any of its excipients. It should also be avoided in individuals currently taking monoamine oxidase inhibitors (MAOIs) or who have a history of severe allergic reactions to similar antidepressants. Caution is advised in patients with hepatic impairment or uncontrolled hypertension.