Product image of Mirtazapine Focus Pharmaceuticals Ltd (Mirtazapine) supplied by GNH India

Mirtazapine Focus Pharmaceuticals Ltd

Active Ingredient:
Mirtazapine
Origin:
EU

Mirtazapine Focus Pharmaceuticals Ltd (Mirtazapine)

Mirtazapine, the active ingredient in Mirtazapine Focus Pharmaceuticals Ltd, is a tetracyclic antidepressant presented as an oral tablet for oral use. It is prescribed for the treatment of major depressive disorder in adult patients and is manufactured under EU GMP standards as a prescription‑only medicine.

GNH India supplies Mirtazapine Focus Pharmaceuticals Ltd as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Focus Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Mirtazapine is indicated for depressive disorders and works by modulating neurotransmitter activity.
  • Major depressive disorder: alleviates depressive symptoms and improves mood in adult patients.

How It Works

  • Mirtazapine acts as an antagonist of central presynaptic α2‑adrenergic receptors, which increases norepinephrine and serotonin release. It also blocks 5‑HT2 and 5‑HT3 receptors and potently antagonises H1 histamine receptors, contributing to its antidepressant and sedative properties.

Side Effects

Mirtazapine may cause a range of adverse reactions that are classified by frequency.

Common Side Effects

  • Sedation: drowsiness or sleepiness, especially at treatment initiation.
  • Increased appetite and weight gain: heightened hunger leading to weight increase.
  • Dry mouth: reduced salivation causing oral dryness.
  • Constipation: slowed gastrointestinal motility.
  • Dizziness: light‑headed sensation on standing.

Serious or Rare Side Effects

  • Severe neutropenia: marked reduction in white blood cells.
  • Serotonin syndrome: potentially life‑threatening reaction when combined with serotonergic agents.
  • Hypotension: significant drop in blood pressure causing faintness.
  • Suicidal thoughts: emergence or worsening of suicidal ideation.

Precautions & Warnings

Before prescribing Mirtazapine, clinicians should consider several safety factors.

  • Pregnancy: safety not established; use only if benefits outweigh risks.
  • Breastfeeding: unknown excretion; consider alternatives.
  • Elderly patients: monitor for increased sedation and falls.
  • History of bipolar disorder: risk of mood switching to mania.
  • Concomitant CNS depressants: may enhance sedative effects.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Mirtazapine interacts with several drug classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis; discontinue MAOI at least 14 days before starting.
  • Serotonergic agents (SSRIs, SNRIs, triptans): risk of serotonin syndrome.
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): may increase mirtazapine plasma levels.
  • Alcohol: additive CNS depression.
  • CNS depressants (benzodiazepines, opioids): heightened sedation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (rifampicin, carbamazepine): may reduce effectiveness.
  • Anticholinergic drugs: additive dry mouth.
  • Antihypertensives: possible additive hypotensive effect.
  • Lithium: monitor for increased sedation.
  • Warfarin: monitor INR as mirtazapine may affect clotting.

Frequently Asked Questions

Mirtazapine is used primarily to treat major depressive disorder in adult patients. It helps alleviate depressive symptoms such as low mood, loss of interest, and sleep disturbances by influencing neurotransmitter activity in the brain.

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine and serotonin. It also antagonises 5‑HT2, 5‑HT3 and H1 histamine receptors, contributing to its antidepressant and sedative effects.

The dose of Mirtazapine is individualized and set by the prescribing clinician based on the patient’s condition, response, and tolerability. Dosage adjustments are made during treatment to achieve optimal therapeutic effect.

Safety of Mirtazapine during pregnancy and lactation has not been conclusively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and alternative treatments should be considered when possible.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with selective serotonin reuptake inhibitors, Mirtazapine has a distinct receptor profile that often results in stronger sedative and appetite‑stimulating effects. It may be preferred when insomnia or weight loss are concerns, but individual response varies and choice should be guided by clinical assessment.

Mirtazapine tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep out of reach of children and do not use after the expiry date.

Mirtazapine is taken orally, usually once daily in the evening due to its sedative properties. It should be swallowed whole with water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include the development of severe neutropenia, serotonin syndrome when combined with other serotonergic drugs, significant hypotension, and the emergence or worsening of suicidal thoughts, especially during early treatment or dose changes.

Mirtazapine is contraindicated in patients taking monoamine oxidase inhibitors, those with known hypersensitivity to the drug, and individuals with a history of severe allergic reactions to similar compounds. Caution is also advised for patients with uncontrolled hypertension or severe hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Mirtazapine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT