Product image of Mirtazapine Rosemont Pharmaceuticals (Mirtazapine) supplied by GNH India

Mirtazapine Rosemont Pharmaceuticals

Active Ingredient:
Mirtazapine
Origin:
EU

Mirtazapine Rosemont Pharmaceuticals (Mirtazapine)

Mirtazapine, the active ingredient in Mirtazapine Rosemont Pharmaceuticals, is a tetracyclic antidepressant presented as an unspecified strength/tablet for oral use. It is indicated for the treatment of major depressive disorder in adult patients.

GNH India supplies Mirtazapine Rosemont Pharmaceuticals as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rosemont Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mirtazapine is a tetracyclic antidepressant used primarily in the management of depressive disorders.

  • Major depressive disorder: reduces depressive symptoms and improves overall mood.
  • Depressive episodes in bipolar disorder (adjunct): helps alleviate depressive phases when used with mood stabilisers.
  • Depression with insomnia: promotes sleep and may improve appetite, aiding recovery.

How It Works

  • Mirtazapine acts as an antagonist of central presynaptic α2‑adrenergic receptors, which increases norepinephrine release, and blocks postsynaptic 5‑HT2 and 5‑HT3 receptors, enhancing serotonergic neurotransmission while reducing serotonergic side‑effects. This combined action contributes to its antidepressant and anxiolytic effects.

Side Effects

Mirtazapine may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Sedation or drowsiness
  • Increased appetite and weight gain
  • Dry mouth
  • Constipation
  • Dizziness
  • Peripheral edema

Serious or Rare Side Effects

  • Agranulocytosis or severe neutropenia
  • Hepatic dysfunction or jaundice
  • Suicidal thoughts or behavior
  • Severe rash or Stevens‑Johnson syndrome
  • Seizures
  • Hyponatraemia

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Assess suicidality: monitor patients for worsening depression or emergence of suicidal thoughts.
  • Avoid abrupt discontinuation: taper under medical supervision to reduce withdrawal symptoms.
  • Caution in hepatic impairment: dose adjustment may be required.
  • Use with caution in elderly: increased risk of sedation and falls.
  • Avoid concomitant MAO inhibitors: risk of hypertensive crisis and serotonin syndrome.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Mirtazapine can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis and serotonin syndrome.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase mirtazapine plasma concentrations.
  • Strong CYP3A4 inducers (e.g., rifampin): may reduce therapeutic efficacy.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression.
  • Other CNS depressants (e.g., benzodiazepines): additive sedation.
  • Anticoagulants (e.g., warfarin): potential increase in bleeding risk.

Frequently Asked Questions

Mirtazapine Rosemont Pharmaceuticals is a prescription tetracyclic antidepressant indicated for the treatment of major depressive disorder in adult patients. It may also be used as an adjunct in depressive episodes of bipolar disorder and to improve sleep in patients with depression‑related insomnia.

Mirtazapine increases neurotransmission by blocking presynaptic α2‑adrenergic receptors, which raises norepinephrine release, and by antagonising postsynaptic 5‑HT2 and 5‑HT3 receptors, enhancing serotonergic activity while reducing certain serotonin‑mediated side effects.

The appropriate dose of mirtazapine is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. Dosage adjustments are made according to professional guidelines and patient-specific factors.

Safety data for mirtazapine in pregnancy and lactation are limited. Clinicians should weigh potential benefits against possible risks and consider alternative therapies when treating pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with selective serotonin reuptake inhibitors, mirtazapine has a distinct receptor profile that often results in greater sedation and appetite stimulation, which can be advantageous for patients with insomnia or weight loss. Its side‑effect spectrum differs, and it may be preferred when those specific effects are clinically desirable.

Mirtazapine Rosemont Pharmaceuticals should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain stability.

Mirtazapine is taken orally, usually once daily in the evening due to its sedative properties. The tablet should be swallowed whole with water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include agranulocytosis, severe hepatic dysfunction, hyponatraemia, and the emergence or worsening of suicidal thoughts, especially during early treatment or dose changes. Patients should be monitored closely for these rare but critical adverse events.

Mirtazapine is contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or those with known hypersensitivity to the drug. Caution is advised for individuals with severe hepatic impairment, uncontrolled epilepsy, or a history of severe allergic reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.