Product image of Mirtazapine Teva (Mirtazapine) supplied by GNH India

Mirtazapine Teva

Active Ingredient:
Mirtazapine
Origin:
EU

Mirtazapine Teva (Mirtazapine)

Mirtazapine, the active ingredient in Mirtazapine Teva, is a NaSSA (noradrenergic and specific serotonergic antidepressant) presented as an oral tablet for oral use. It treats major depressive disorder in adult patients.
GNH India supplies Mirtazapine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Mirtazapine Teva belongs to the NaSSA class and is indicated for depressive disorders.

  • Major depressive disorder: reduces depressive symptoms and improves mood in adults.

How It Works

  • Mirtazapine blocks central presynaptic α2‑adrenergic receptors, increasing norepinephrine release, and antagonizes postsynaptic 5‑HT2 and 5‑HT3 receptors while strongly inhibiting H1 histamine receptors, resulting in enhanced serotonergic and noradrenergic neurotransmission and sedation.

Side Effects

Mirtazapine may cause a range of adverse reactions.

Common Side Effects

  • Sedation or drowsiness
  • Increased appetite and weight gain
  • Dry mouth
  • Constipation
  • Dizziness
  • Somnolence

Serious or Rare Side Effects

  • Agranulocytosis or severe neutropenia
  • Leukopenia
  • Hypersensitivity reactions such as rash or angioedema
  • Suicidal thoughts or behavior, especially early in treatment
  • Seizures

Precautions & Warnings

Before prescribing Mirtazapine Teva, clinicians should consider several safety aspects.

  • Hepatic impairment: dose may need adjustment
  • Monitor weight and metabolic parameters regularly
  • Caution in patients with a history of bipolar disorder or mania
  • Avoid abrupt discontinuation to reduce withdrawal symptoms
  • Pregnancy and lactation: risk unknown, use only if benefit outweighs potential harm
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Mirtazapine Teva can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis
  • Central nervous system depressants (alcohol, benzodiazepines): enhanced sedation
  • Strong CYP2D6 inhibitors (e.g., fluoxetine): increased plasma concentrations

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., carbamazepine): reduced efficacy
  • Anticholinergic agents: additive dry mouth
  • Other serotonergic drugs (SSRIs, SNRIs, tramadol): potential serotonin syndrome

Frequently Asked Questions

Mirtazapine Teva is prescribed for the treatment of major depressive disorder in adult patients. It belongs to the NaSSA class of antidepressants and helps alleviate depressive symptoms such as low mood, loss of interest, and sleep disturbances.

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine, and by antagonising postsynaptic 5‑HT2 and 5‑HT3 receptors. Its strong H1‑histamine antagonism also contributes to its sedative effect.

The appropriate dose of Mirtazapine Teva is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. Patients should follow the dosage instructions provided by their healthcare professional.

Safety data for Mirtazapine Teva in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Mirtazapine Teva, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with selective serotonin reuptake inhibitors (SSRIs), mirtazapine has a different receptor profile, offering strong antihistamine‑mediated sedation and appetite stimulation. It may be preferred when patients experience insomnia or weight loss, while SSRIs are often chosen for their lower risk of weight gain.

Mirtazapine Teva tablets should be stored at ambient temperature below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date.

Mirtazapine Teva is taken orally, usually once daily in the evening. Tablets should be swallowed whole with water and not crushed or chewed, unless otherwise directed by a healthcare professional.

Serious risks include agranulocytosis or severe neutropenia, hypersensitivity reactions such as rash or angioedema, emergence of suicidal thoughts especially early in treatment, and rare seizures. Patients should seek immediate medical attention if any of these occur.

Mirtazapine Teva should be avoided in patients with known hypersensitivity to mirtazapine or any of its excipients, those currently taking monoamine oxidase inhibitors, and individuals with uncontrolled severe cardiovascular disease. Caution is also advised for patients with a history of bipolar disorder.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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