Product image of Mirvaso (Brimonidine Tartrate) supplied by GNH India

Mirvaso

Active Ingredient:
Brimonidine Tartrate
Origin:
EU

Mirvaso (Brimonidine Tartrate)

Brimonidine tartrate, the active ingredient in Mirvaso, is a Alpha-2 adrenergic agonist presented as a 0.33% (w/w) gel for topical use. It treats persistent facial erythema associated with rosacea in adults. The formulation is designed for once‑daily application to the affected facial areas, providing a localized vasoconstrictive effect that reduces visible redness.

GNH India supplies Mirvaso as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established quality‑assurance processes and regulatory support for cross‑border distribution global.

Manufacturer / TM Owner

Galderma International

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mirvaso (brimonidine tartrate) is indicated for the management of persistent facial erythema in rosacea, a chronic inflammatory skin condition.

  • Persistent facial erythema associated with rosacea: Reduces visible redness and improves facial appearance.
  • Transient facial flushing in rosacea: Decreases frequency and intensity of flushing episodes.
  • Overall rosacea‑related redness: Provides adjunctive control of cutaneous vasodilation.

How It Works

  • Brimonidine tartrate selectively activates alpha‑2 adrenergic receptors on cutaneous vascular smooth muscle. This activation reduces cyclic AMP levels, leading to vasoconstriction of superficial blood vessels in the skin. The localized narrowing of these vessels diminishes blood flow to the affected facial areas, thereby decreasing the visible redness characteristic of rosacea. The gel formulation allows direct delivery to the skin, maximizing the vasoconstrictive effect while limiting systemic exposure.

Side Effects

Adverse reactions reported with Mirvaso are generally mild to moderate and reflect local skin tolerance.

Common Side Effects

  • Application site irritation: mild redness, burning or stinging at the site of application.
  • Dryness: sensation of skin dryness or flaking.
  • Pruritus: itching of the treated area.

Serious or Rare Side Effects

  • Allergic contact dermatitis: rash, swelling, or severe itching requiring medical attention.
  • Hypotension: systemic absorption leading to low blood pressure, rarely observed.
  • Cardiovascular events: chest pain or palpitations in susceptible individuals.

Precautions & Warnings

Before using Mirvaso, consider the following precautions.

  • Pregnancy: safety not established; avoid use unless benefits outweigh risks.
  • Breastfeeding: unknown excretion; discuss with healthcare provider.
  • Concurrent rosacea therapies: assess for additive irritation when combined with other topical agents.
  • Skin integrity: do not apply to broken, infected, or inflamed skin.
  • Allergy history: avoid if known hypersensitivity to brimonidine or formulation components.
  • Store at room temperature: keep in original tube, protect from light and moisture.

Avoid Interactions

Mirvaso may interact with other agents that affect vascular tone or systemic adrenergic activity.

Major Interactions (Avoid)

  • Systemic alpha‑2 agonists (e.g., clonidine): additive vasoconstrictive effect may increase blood pressure changes.
  • Non‑selective beta‑blockers: potential for enhanced hypotensive response.

Moderate Interactions (Monitor Closely)

  • Topical irritants (e.g., retinoids, benzoyl peroxide): may increase local skin irritation.
  • Other vasoconstrictive agents (e.g., phenylephrine nasal sprays): monitor for excessive vasoconstriction.

Frequently Asked Questions

Mirvaso is a prescription gel containing brimonidine tartrate that is used to reduce persistent facial erythema associated with rosacea. It works by narrowing the superficial blood vessels that cause visible redness, helping improve the appearance of the skin in adult patients with this chronic condition.

Brimonidine is a selective alpha‑2 adrenergic receptor agonist. When applied to the skin, it activates these receptors on vascular smooth muscle, lowering cyclic AMP levels and causing the small blood vessels to constrict. This vasoconstriction reduces blood flow to the facial skin, thereby diminishing the redness characteristic of rosacea.

The dosing regimen for Mirvaso is determined by the prescribing healthcare professional. Typically, a thin layer is applied to the affected facial areas once daily, but the exact amount, frequency, and duration should follow the prescriber’s instructions and the product label.

Safety of Mirvaso during pregnancy and lactation has not been established. The product label advises avoiding use unless the potential benefit justifies the potential risk. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their healthcare provider.

To order Mirvaso, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details and any necessary import documentation.

Mirvaso’s active ingredient, brimonidine, belongs to the alpha‑2 adrenergic agonist class, whereas many other topical rosacea agents, such as metronidazole or azelaic acid, act as anti‑inflammatory or antimicrobial agents. Brimonidine provides rapid, short‑term reduction of erythema through vasoconstriction, while the alternatives mainly target inflammation and may require longer treatment periods.

Mirvaso should be stored at room temperature, preferably below 25 °C, in its original tube. Keep the container tightly closed, protect it from direct sunlight and moisture, and avoid freezing. Do not use the product after the expiry date printed on the packaging.

Apply a thin layer of Mirvaso gel to the affected facial areas once daily, usually in the morning or as directed by a healthcare professional. Gently spread the gel over clean, dry skin, avoiding the eyes, mouth and any broken or irritated skin. Wash hands after application.

Serious but rare risks include allergic contact dermatitis, systemic hypotension from excessive absorption, and cardiovascular events such as chest pain or palpitations. Patients should seek immediate medical attention if they experience widespread rash, swelling, severe dizziness, or any signs of low blood pressure.

Mirvaso should not be used by individuals with known hypersensitivity to brimonidine tartrate or any component of the gel formulation. It is also contraindicated on broken, infected or severely inflamed skin, and should be avoided in patients where systemic vasoconstriction could be harmful, such as those with uncontrolled hypertension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.