Product image of Mirvedol (Memantine Hydrochloride) supplied by GNH India

Mirvedol

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Mirvedol (Memantine Hydrochloride)

Memantine Hydrochloride, the active ingredient in Mirvedol, is an NMDA receptor antagonist presented as an oral formulation for oral use. It is indicated for the treatment of moderate to severe Alzheimer’s disease in adults.

GNH India supplies Mirvedol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Gedeon Richter Plc.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Mirvedol acts on the glutamatergic pathway involved in neurodegeneration, primarily used in Alzheimer’s disease management.
  • Alzheimer’s disease (moderate to severe): improves cognition and functional abilities.
  • Alzheimer’s disease with behavioral symptoms: may reduce agitation and confusion.
  • Dementia associated with Alzheimer’s disease: supports daily living activities.

How It Works

  • Memantine Hydrochloride is a non‑competitive antagonist of the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor-associated ion channel, it reduces excessive calcium influx caused by prolonged glutamate activation, thereby limiting excitotoxic neuronal injury that contributes to cognitive decline in Alzheimer’s disease.

Side Effects

Common Side Effects

  • Dizziness: mild to moderate sensation of light‑headedness.
  • Headache: transient cranial pain.
  • Constipation: reduced bowel movements.
  • Fatigue: feeling of tiredness or reduced energy.
  • Confusion: occasional disorientation.
  • Somnolence: increased sleepiness.

Serious or Rare Side Effects

  • Seizures: convulsive episodes requiring immediate medical attention.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Hallucinations or psychosis: visual or auditory disturbances.
  • Suicidal thoughts: emergence of depressive ideation.
  • Cardiac arrhythmias: irregular heart rhythm in susceptible patients.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Renal impairment: assess kidney function and monitor.
  • Hepatic impairment: use with caution in liver disease.
  • History of seizures: monitor for increased seizure activity.
  • Concomitant NMDA‑active agents: avoid additive CNS effects.
  • Pregnancy and breastfeeding: safety unknown; avoid unless clearly needed.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Memantine may interact with several medicines; review patient medication lists carefully.

Major Interactions (Avoid)

  • Amantadine: additive NMDA antagonism may increase neurotoxicity.
  • Ketamine: combined CNS depression and altered perception.
  • Other NMDA antagonists: risk of excessive inhibition.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may exacerbate confusion.
  • CNS depressants (e.g., benzodiazepines): enhanced drowsiness.
  • Diuretics: potential impact on blood pressure and electrolyte balance.

Frequently Asked Questions

Mirvedol contains memantine hydrochloride and is prescribed for adults with moderate to severe Alzheimer’s disease. It helps improve cognitive function and daily living activities by reducing excitotoxic neuronal damage associated with the disease.

Memantine acts as a non‑competitive antagonist at the NMDA receptor, blocking excessive calcium influx caused by prolonged glutamate stimulation. This reduces excitotoxic neuronal injury, which is a key factor in the progression of Alzheimer’s disease.

The specific dose of Mirvedol is determined by the prescribing clinician based on the patient’s clinical condition, renal function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of memantine hydrochloride in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.

To order Mirvedol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Mirvedol (memantine) belongs to the NMDA receptor antagonist class, which differs from acetylcholinesterase inhibitors such as donepezil. While both improve symptoms, memantine is typically used in moderate to severe stages and may be combined with an acetylcholinesterase inhibitor for additive benefit.

Mirvedol should be stored at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Mirvedol is taken orally, usually once daily with or without food, as directed by the prescriber. The tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious risks include the potential for seizures, severe allergic reactions such as anaphylaxis, and rare neuropsychiatric events like hallucinations or suicidal thoughts. Patients should seek immediate medical attention if any of these symptoms occur.

Mirvedol is contraindicated in patients with known hypersensitivity to memantine or any component of the formulation. Caution is advised for individuals with severe renal impairment, uncontrolled epilepsy, or those taking other NMDA antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Memantine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT