Mirzaten (Mirtazapine)

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases the release of norepinephrine. It also antagonizes several serotonin receptors (5‑HT2 and 5‑HT3) and the histamine H1 receptor, resulting in enhanced serotonergic and noradrenergic neurotransmission while providing sedative and appetite‑stimulating effects.

The dose of Mirzaten is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. The prescriber will select the appropriate strength and dosing schedule, which may be adjusted over time as needed.

The safety of mirtazapine in pregnancy and lactation has not been definitively established. Healthcare providers should weigh the potential benefits against possible risks and consider alternative treatments when appropriate. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss their situation with a qualified medical professional.

To place an order, submit an enquiry on the Mirzaten product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After verification, the team will provide pricing, availability, shipping details, and any necessary import documentation.

Compared with selective serotonin reuptake inhibitors (SSRIs), mirtazapine has a distinct mechanism that includes antihistaminic activity, often leading to sedation and weight gain. It may be preferred when patients experience insomnia or poor appetite, whereas SSRIs are generally less sedating. Choice of therapy depends on individual symptom profile, side‑effect tolerance, and clinical judgment.

Mirzaten tablets should be stored at ambient temperature, below 25 °C, in their original container to protect from moisture and light. Keep the product out of reach of children and avoid storing in humid environments such as bathrooms.

Mirzaten is taken orally, usually once daily in the evening due to its sedative properties. The tablet should be swallowed whole with water and not chewed or crushed unless otherwise directed by a healthcare professional.

Serious risks include the potential for agranulocytosis or severe neutropenia, which can lead to infections, as well as the emergence of suicidal thoughts or behaviors, especially when therapy is initiated or dosage is changed. Rarely, hypersensitivity reactions, hepatic dysfunction, and serotonin syndrome (when combined with other serotonergic drugs) may occur.

Mirzaten is contraindicated in patients with known hypersensitivity to mirtazapine or any of its excipients. It should also be avoided in individuals currently taking monoamine oxidase inhibitors (MAOIs) or those who have experienced severe adverse reactions to similar antidepressants. Clinicians should assess each patient’s medical history before prescribing.