Product image of Mirzaten Q-Tab (Mirtazapine) supplied by GNH India

Mirzaten Q-Tab

Active Ingredient:
Mirtazapine
Origin:
EU

Mirzaten Q-Tab (Mirtazapine)

Mirtazapine, the active ingredient in Mirzaten Q-Tab, is a NaSSA (noradrenergic and specific serotonergic antidepressant) presented as a tablet for oral use. It is prescribed for the treatment of major depressive disorder in adult patients.

GNH India supplies Mirzaten Q-Tab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka-Farma D.O.O.

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Indications & Clinical Uses

Mirtazapine is a noradrenergic and specific serotonergic antidepressant used primarily in the management of depressive disorders.

  • Major depressive disorder: reduces depressive symptoms and improves mood in adults.
  • Depressive disorder with anxiety: alleviates both mood and anxiety components.
  • Treatment‑resistant depression: used as an adjunct when first‑line agents are insufficient.

How It Works

  • Mirtazapine acts as an antagonist at central presynaptic α2‑adrenergic receptors, increasing norepinephrine and serotonin release. It also blocks postsynaptic 5‑HT2 and 5‑HT3 receptors while providing potent H1‑receptor antagonism, which together enhance antidepressant activity and contribute to its sedative profile.

Side Effects

Mirtazapine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Sedation or drowsiness
  • Increased appetite and weight gain
  • Dry mouth
  • Constipation
  • Dizziness

Serious or Rare Side Effects

  • Agranulocytosis or severe neutropenia
  • Hypersensitivity reactions including Stevens‑Johnson syndrome
  • Suicidal thoughts or behavior, especially early in therapy
  • Hepatic dysfunction
  • Severe hypotension

Precautions & Warnings

When prescribing Mirzaten Q-Tab, clinicians should consider several safety measures.

  • Monitor weight: patients often experience increased appetite and weight gain.
  • Assess liver function: use with caution in hepatic impairment.
  • Evaluate for suicidal ideation: close monitoring during the initial treatment period.
  • Use cautiously in the elderly: heightened risk of sedation and falls.
  • Avoid abrupt discontinuation: taper the dose under medical supervision.
  • Store at ambient temperature: keep in the original container, protect from moisture.

Avoid Interactions

Mirtazapine can interact with other medicines, requiring careful review.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other serotonergic antidepressants: potential serotonin syndrome.
  • Potent CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): may increase mirtazapine levels.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole) or inducers (e.g., rifampin): may alter plasma concentrations.
  • Anticoagulants such as warfarin: monitor INR.
  • CNS depressants (e.g., benzodiazepines, alcohol): may enhance sedation.

Frequently Asked Questions

Mirzaten Q-Tab contains mirtazapine, an antidepressant indicated for the treatment of major depressive disorder in adult patients. It may also be used for depressive episodes with prominent anxiety or when other antidepressants have not provided adequate relief.

Mirtazapine increases the release of norepinephrine and serotonin by blocking presynaptic α2‑adrenergic receptors. It also antagonizes postsynaptic 5‑HT2 and 5‑HT3 receptors and provides strong H1‑receptor blockade, which together produce antidepressant and sedative effects.

The appropriate dose of Mirzaten Q-Tab is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. Dosage adjustments are made according to professional guidelines and patient needs.

The safety of mirtazapine in pregnancy and lactation has not been definitively established. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and decisions are made in consultation with a healthcare professional.

To place an order, submit an enquiry on the Mirzaten Q-Tab product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with selective serotonin reuptake inhibitors (SSRIs), mirtazapine has a distinct mechanism involving α2‑adrenergic antagonism and H1‑receptor blockade, which often results in greater sedation and appetite stimulation. This profile can be advantageous for patients with insomnia or weight loss, but may be less suitable for those concerned about weight gain.

Mirzaten Q-Tab tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect the tablets from moisture and direct sunlight to maintain product stability.

The tablet is taken orally, usually once daily in the evening or as directed by a healthcare provider. It should be swallowed whole with water and not crushed or chewed unless specifically instructed.

Serious risks include agranulocytosis or severe neutropenia, hypersensitivity reactions such as Stevens‑Johnson syndrome, significant hepatic dysfunction, and the emergence or worsening of suicidal thoughts, particularly during the early weeks of therapy.

Patients with known hypersensitivity to mirtazapine or any of its excipients, those currently taking monoamine oxidase inhibitors, or individuals with severe hepatic impairment should avoid Mirzaten Q-Tab unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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