Product image of Mirzaten Q-Tab (Mirtazapine) supplied by GNH India

Mirzaten Q-Tab

Active Ingredient:
Mirtazapine
Origin:
EU

Mirzaten Q-Tab (Mirtazapine)

Mirtazapine, the active ingredient in Mirzaten Q-Tab, is a NaSSA (noradrenergic and specific serotonergic antidepressant) presented as an oral tablet for oral use. It belongs to the class of noradrenergic and specific serotonergic antidepressants and is used to treat major depressive disorder in adult patients, improving mood and sleep quality.

GNH India supplies Mirzaten Q-Tab as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU quality standards, and serves hospitals, pharmacies and clinics worldwide with reliable sourcing and regulatory support.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Mirtazapine is a noradrenergic and specific serotonergic antidepressant used primarily in the management of depressive disorders.

  • Major depressive disorder: alleviates depressive symptoms, improves mood and sleep.
  • Depression with insomnia: promotes sleep onset and reduces nighttime awakenings.
  • Depression with anxiety: helps reduce anxiety symptoms associated with depressive episodes.

How It Works

  • Mirtazapine acts as an antagonist at central presynaptic α2‑adrenergic receptors, thereby increasing norepinephrine release, and blocks 5‑HT2 and 5‑HT3 receptors while antagonizing H1 histamine receptors. This combined activity enhances noradrenergic and serotonergic neurotransmission and produces sedative and anxiolytic effects that contribute to its antidepressant action.

Side Effects

Mirtazapine may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Sedation: feeling of drowsiness or sleepiness.
  • Increased appetite and weight gain: heightened hunger leading to weight increase.
  • Dry mouth: reduced salivation causing oral dryness.
  • Constipation: slowed intestinal transit resulting in hard stools.

Serious or Rare Side Effects

  • Agranulocytosis: severe reduction in white blood cells requiring immediate medical attention.
  • Suicidal thoughts: emergence of suicidal ideation, especially early in treatment.
  • Severe allergic reactions: rash, swelling, or difficulty breathing indicating hypersensitivity.

Precautions & Warnings

When prescribing Mirtazapine, clinicians should consider several safety precautions.

  • Pregnancy: consult a healthcare provider as safety data are limited.
  • Elderly patients: monitor for excessive sedation and increased fall risk.
  • History of bipolar disorder: may trigger mood switching to mania.
  • Liver impairment: dose adjustment may be necessary due to altered metabolism.
  • Concomitant CNS depressants: may enhance sedative effects.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Mirtazapine can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis or serotonin syndrome.
  • Other serotonergic agents: may increase serotonin syndrome risk.

Moderate Interactions (Monitor Closely)

  • CYP2D6 inhibitors (e.g., fluoxetine): can raise mirtazapine plasma levels.
  • CYP inducers (e.g., carbamazepine): may reduce effectiveness.
  • CNS depressants (e.g., alcohol, benzodiazepines): enhance sedation.

Frequently Asked Questions

Mirzaten Q-Tab contains mirtazapine, which is prescribed to treat major depressive disorder in adult patients. It helps improve mood, sleep quality, and overall functional status by modulating neurotransmitter activity in the brain.

Mirtazapine works by blocking presynaptic α2‑adrenergic receptors, which increases norepinephrine release, and by antagonizing 5‑HT2, 5‑HT3 and H1 receptors. This combined effect enhances serotonergic and noradrenergic transmission while providing sedative and anxiolytic benefits.

The appropriate dose of Mirzaten Q-Tab is determined by the prescribing healthcare professional based on the individual’s clinical condition, response to therapy, and tolerability. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for mirtazapine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Mirzaten Q-Tab.

To place an order, submit an enquiry on the Mirzaten Q-Tab product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with selective serotonin reuptake inhibitors (SSRIs), mirtazapine has a distinct receptor profile that often results in stronger sedative and appetite‑stimulating effects. This can be advantageous for patients with insomnia or weight loss, but may be less suitable for those who wish to avoid these side effects.

Mirzaten Q-Tab should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat and direct sunlight to maintain product stability throughout its shelf life.

Mirzaten Q-Tab is taken orally, usually once daily in the evening with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include the potential for agranulocytosis, severe allergic reactions, and the emergence of suicidal thoughts, particularly during the initial weeks of therapy. Patients should be monitored closely for any signs of infection, hypersensitivity, or worsening mood.

Individuals with known hypersensitivity to mirtazapine or any of its excipients, those currently taking monoamine oxidase inhibitors, or patients with uncontrolled severe liver disease should avoid using Mirzaten Q-Tab. A healthcare professional should evaluate suitability for all other patients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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