Product image of Mivuxin (Noradrenaline Tartrate) supplied by GNH India

Mivuxin

Active Ingredient:
Noradrenaline Tartrate
Origin:
EU

Mivuxin (Noradrenaline Tartrate)

Noradrenaline tartrate, the active ingredient in Mivuxin, is a sympathomimetic amine presented as an intravenous solution for intravenous use. It is employed to raise blood pressure in acute hypotensive states such as septic shock and cardiac arrest.
GNH India supplies Mivuxin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mivuxin acts on the sympathetic nervous system to restore vascular tone in critical care settings.

  • Hypotension: increases systemic vascular resistance to achieve target arterial pressure.
  • Septic shock: counteracts vasodilatory shock by constricting peripheral vessels and improving perfusion.
  • Cardiac arrest: provides immediate pressor support during resuscitation to maintain coronary and cerebral blood flow.

How It Works

  • Noradrenaline tartrate is an agonist at alpha‑adrenergic receptors, primarily α1, causing vasoconstriction of arteriolar and venous smooth muscle. This raises systemic vascular resistance and arterial pressure. At higher concentrations it also stimulates β1 receptors, modestly increasing cardiac contractility and heart rate, contributing to overall hemodynamic support in shock states.

Side Effects

Mivuxin may be associated with a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Tachycardia: rapid heart rate due to β1 stimulation.
  • Headache: result of abrupt vascular changes.
  • Anxiety or restlessness: central sympathetic activation.
  • Peripheral ischemia: reduced blood flow to extremities.

Serious or Rare Side Effects

  • Severe hypertension: excessive vasoconstriction leading to organ damage.
  • Myocardial ischemia or infarction: increased cardiac workload.
  • Arrhythmias: potentially life‑threatening rhythm disturbances.
  • Tissue necrosis at infusion site: extravasation injury.

Precautions & Warnings

When using Mivuxin, clinicians should observe several safety measures to minimise risk.

  • Dose titration: adjust infusion rate based on continuous blood pressure monitoring.
  • Cardiovascular monitoring: maintain invasive arterial line and ECG throughout therapy.
  • Contraindications: avoid in patients with pheochromocytoma or uncontrolled hypertension.
  • Drug interactions: review concomitant use of MAO inhibitors or ergot alkaloids.
  • Pregnancy: consider only if potential benefit outweighs fetal risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Noradrenaline tartrate can interact with several agents that modify vascular tone or catecholamine metabolism.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis due to additive catecholamine effects.
  • Ergot alkaloids: potent vasoconstriction may lead to severe ischemia.
  • Tricyclic antidepressants: increased sympathetic activity.

Moderate Interactions (Monitor Closely)

  • Vasodilators (e.g., nitroglycerin): may blunt pressor response, requiring dose adjustments.
  • ACE inhibitors or ARBs: can enhance hypotensive episodes if not carefully titrated.
  • Calcium channel blockers: may affect cardiac output and require close hemodynamic monitoring.

Frequently Asked Questions

Mivuxin is a prescription‑only intravenous vasopressor used in acute care to treat severe hypotension, septic shock, and cardiac arrest. It works by constricting blood vessels and raising systemic vascular resistance, helping to restore adequate blood pressure and organ perfusion in critically ill patients.

Noradrenaline tartrate activates alpha‑adrenergic receptors on vascular smooth muscle, causing vasoconstriction and an increase in systemic vascular resistance. At higher concentrations it also stimulates beta‑1 receptors in the heart, modestly enhancing contractility and heart rate, together supporting blood pressure in shock states.

The dosing regimen for Mivuxin is individualized by the treating physician based on the patient's hemodynamic status, target blood pressure, and response to therapy. Clinicians typically start with a low infusion rate and titrate upward while monitoring arterial pressure and cardiac function.

Safety data for noradrenaline tartrate in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where needed) and import documentation.

Mivuxin (noradrenaline) is often considered the first‑line vasopressor for septic shock because of its potent alpha‑adrenergic activity and relatively predictable hemodynamic profile. Compared with agents such as dopamine or phenylephrine, noradrenaline provides stronger vasoconstriction with less tachyarrhythmia risk, making it a preferred choice in many critical‑care protocols.

Mivuxin should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Before administration, the solution should be inspected for particulate matter and discoloration, and any unused portion should be discarded according to local regulations.

Mivuxin is given exclusively by intravenous infusion. It is typically prepared in a sterile diluent and administered through a calibrated infusion pump, allowing precise titration of the dose to achieve the desired blood pressure response while continuous hemodynamic monitoring is maintained.

The most serious adverse events include severe hypertension, myocardial ischemia or infarction, life‑threatening arrhythmias, and tissue necrosis at the infusion site due to extravasation. Prompt recognition and immediate management of these complications are essential to minimize patient harm.

Mivuxin is contraindicated in patients with known hypersensitivity to noradrenaline or any formulation component, and it should be avoided in individuals with pheochromocytoma or uncontrolled hypertension. Caution is also advised for patients receiving MAO inhibitors or ergot alkaloids due to the risk of extreme vasoconstriction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.