Product image of Moclobemide Sandoz (Moclobemide) supplied by GNH India

Moclobemide Sandoz

Active Ingredient:
Moclobemide
Origin:
EU

Moclobemide Sandoz (Moclobemide)

Moclobemide, the active ingredient in Moclobemide Sandoz, is a monoamine oxidase inhibitor presented as an oral tablet for oral use. It is prescribed for the treatment of major depressive disorder and dysthymia in adult patients. The reversible inhibition of MAO‑A increases neurotransmitter availability, helping to alleviate depressive symptoms.

GNH India supplies Moclobemide Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Moclobemide acts on the monoamine oxidase pathway to treat depressive disorders. It is indicated for:

  • Major depressive disorder: alleviates depressive symptoms and improves mood.
  • Dysthymia (persistent depressive disorder): reduces chronic low mood and enhances daily functioning.
  • Depressive symptoms in adults: provides an alternative treatment option when other antidepressants are unsuitable.

How It Works

  • Moclobemide reversibly inhibits monoamine oxidase A (MAO‑A), the enzyme responsible for breaking down serotonin, norepinephrine and dopamine. By blocking MAO‑A, the drug increases the synaptic concentrations of these neurotransmitters, thereby enhancing mood regulation and reducing depressive symptoms without permanent enzyme inactivation.

Side Effects

Moclobemide may cause a range of adverse reactions. Patients should be aware of both common and serious possibilities.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: transient cranial discomfort.
  • Dizziness: feeling light‑headed, especially on standing.
  • Dry mouth: reduced salivation.

Serious or Rare Side Effects

  • Hypertensive crisis: sudden high blood pressure, often triggered by tyramine‑rich foods.
  • Serotonin syndrome: agitation, hyperthermia, and neuromuscular abnormalities when combined with other serotonergic agents.
  • Severe liver injury: jaundice, elevated liver enzymes.
  • Agranulocytosis: marked reduction in white blood cells, increasing infection risk.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.

Precautions & Warnings

Before initiating Moclobemide, clinicians should consider several safety measures.

  • Assess hepatic function: evaluate liver enzymes to detect pre‑existing impairment.
  • Monitor blood pressure: MAO inhibition can affect vascular tone.
  • Avoid tyramine‑rich foods: prevent hypertensive episodes.
  • Review concomitant serotonergic drugs: reduce risk of serotonin syndrome.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Moclobemide interacts with several medication classes; some combinations must be avoided while others require close monitoring.

Major Interactions (Avoid)

  • Selective serotonin reuptake inhibitors (SSRIs): risk of serotonin syndrome.
  • Meperidine or other opioids: may precipitate severe hypertension.

Moderate Interactions (Monitor Closely)

  • Tricyclic antidepressants: can increase serotonergic activity.
  • Sympathomimetic agents (e.g., pseudoephedrine): may raise blood pressure.
  • St. John’s wort: may potentiate MAO inhibition and increase adverse effects.

Frequently Asked Questions

Moclobemide Sandoz contains the active ingredient moclobemide, a reversible monoamine oxidase A inhibitor indicated for the treatment of major depressive disorder and dysthymia in adult patients. It helps improve mood by increasing levels of key neurotransmitters in the brain.

Moclobemide works by reversibly inhibiting the enzyme monoamine oxidase A (MAO‑A). This enzyme normally breaks down serotonin, norepinephrine and dopamine. By blocking MAO‑A, moclobemide raises the concentrations of these neurotransmitters, which can alleviate depressive symptoms.

The appropriate dose of Moclobemide Sandoz is determined by the prescribing healthcare professional based on the individual’s clinical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for moclobemide in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers should discuss individual risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Moclobemide differs from many antidepressants because it is a reversible MAO‑A inhibitor, offering a lower risk of dietary tyramine interactions compared with irreversible MAO inhibitors. It may be chosen when patients need an alternative to selective serotonin reuptake inhibitors or tricyclic antidepressants, especially if those agents are ineffective or poorly tolerated.

Moclobemide Sandoz should be stored at room temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat and direct sunlight to maintain product stability throughout its shelf life.

Moclobemide Sandoz is taken orally, usually with or without food, as directed by the prescriber. The tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed by a healthcare professional.

The most serious risks include hypertensive crisis triggered by high‑tyramine foods, serotonin syndrome when combined with other serotonergic drugs, severe liver injury, agranulocytosis, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should be educated to seek immediate medical attention if these symptoms occur.

Moclobemide is contraindicated in patients with known hypersensitivity to moclobemide or any formulation components, those currently taking other MAO inhibitors, and individuals with severe liver impairment. Caution is also advised for patients with uncontrolled hypertension, pheochromocytoma, or a history of serotonin syndrome.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.