Moclobemide Sandoz Ltd (Moclobemide)

Moclobemide works by reversibly inhibiting the enzyme monoamine oxidase A (MAO‑A). This inhibition prevents the breakdown of serotonin, norepinephrine, and dopamine, leading to higher concentrations of these neurotransmitters and an improvement in mood and anxiety symptoms.

The appropriate dose of Moclobemide is determined by the prescribing clinician based on the individual’s condition, response, and tolerability. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the dose on their own.

The safety of Moclobemide in pregnancy and lactation has not been definitively established. Healthcare providers usually weigh the potential benefits against possible risks before prescribing it to pregnant or nursing women, and alternative treatments may be considered.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike irreversible MAO inhibitors, Moclobemide is reversible, which generally results in fewer dietary restrictions and a lower risk of severe hypertensive reactions. Compared with selective serotonin reuptake inhibitors, it affects three neurotransmitters (serotonin, norepinephrine, dopamine), offering a broader mechanism of action.

Moclobemide should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct light. Keeping the product in a dry, cool environment helps maintain its stability and potency.

Moclobemide is taken orally, usually with or without food, as directed by a healthcare professional. The tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

The most serious risks include hypertensive crisis triggered by high‑tyramine foods, serotonin syndrome when combined with other serotonergic agents, and rare cases of severe liver injury. Patients should be educated about these risks and seek immediate medical attention if symptoms arise.

Moclobemide is contraindicated in individuals with known hypersensitivity to the drug, those taking certain serotonergic medications (e.g., SSRIs, tricyclic antidepressants) without proper washout periods, and patients with severe liver impairment. A thorough medical review is essential before initiating therapy.