Product image of Modafen Extra Grip (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Modafen Extra Grip

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Modafen Extra Grip (Pseudoephedrine Hydrochloride, Ibuprofen)

Pseudoephedrine hydrochloride and ibuprofen, the active ingredients in Modafen Extra Grip, are a decongestant and non‑steroidal anti‑inflammatory drug (NSAID) combination presented as an oral dosage form for oral use. They relieve nasal congestion, headache, fever and pain associated with the common cold or flu in adults and adolescents.

GNH India supplies Modafen Extra Grip as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution across multiple continents.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Modafen Extra Grip, a pseudoephedrine/ibuprofen combination, addresses multiple symptoms within the cold and flu disease family, offering both decongestant and analgesic effects.

  • Nasal congestion: reduces swelling of nasal passages, improving airflow.
  • Headache: alleviates pain associated with tension or sinus pressure.
  • Fever: lowers elevated body temperature.
  • Cold‑related pain: eases sore throat, sinus and muscle aches.
  • Body aches: provides anti‑inflammatory relief for muscle soreness linked to flu.

How It Works

  • Pseudoephedrine hydrochloride acts as a sympathomimetic amine that stimulates α‑adrenergic receptors in the nasal mucosa, causing vasoconstriction and reduced edema. Ibuprofen inhibits cyclo‑oxygenase enzymes COX‑1 and COX‑2, decreasing prostaglandin synthesis, which provides analgesic, antipyretic and anti‑inflammatory actions. By limiting inflammatory mediators, ibuprofen also helps to lower the hypothalamic set‑point for temperature regulation, contributing to fever reduction.

Side Effects

Like all medicines, Modafen Extra Grip may cause unwanted reactions, which are classified by frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset that usually resolves on its own.
  • Dizziness: transient light‑headedness, especially when standing quickly.
  • Dry mouth: reduced salivation leading to a feeling of thirst.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with swelling, rash and breathing difficulty.
  • Gastrointestinal bleeding: blood in stool or vomiting blood, requiring immediate medical attention.
  • Hypertension: significant rise in blood pressure, particularly in susceptible individuals.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering and detachment.
  • Cardiovascular events: chest pain or arrhythmias in high‑risk patients.

Precautions & Warnings

Before using Modafen Extra Grip, consider the following safety measures.

  • Assess cardiovascular status: avoid in uncontrolled hypertension or severe heart disease.
  • Check gastrointestinal risk: use cautiously in patients with ulcer disease or bleeding history.
  • Renal function: monitor in patients with impaired kidney function.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Drug interactions: review concomitant medications for potential additive effects.
  • Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Modafen Extra Grip can interact with other medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other sympathomimetics: may cause excessive vasoconstriction and cardiovascular stress.
  • Anticoagulants (e.g., warfarin): ibuprofen can increase bleeding risk.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may blunt pseudoephedrine’s decongestant effect.
  • Diuretics: may enhance hypotensive effect of ibuprofen.
  • Lithium: ibuprofen may raise lithium levels, requiring serum monitoring.

Frequently Asked Questions

Modafen Extra Grip is an over‑the‑counter oral medication that combines pseudoephedrine and ibuprofen to relieve nasal congestion, headache, fever and pain associated with the common cold or flu. It provides both decongestant and anti‑inflammatory effects, making it suitable for adults and adolescents experiencing typical cold‑related symptoms.

Pseudoephedrine acts as a sympathomimetic amine that stimulates α‑adrenergic receptors in the blood vessels of the nasal mucosa. This stimulation causes the vessels to constrict, reducing swelling and fluid buildup, which opens the nasal passages and eases congestion. The effect is localized to the upper respiratory tract and lasts several hours.

The appropriate dose of Modafen Extra Grip is determined by a qualified healthcare professional based on the patient’s age, weight, medical history and the severity of symptoms. Because the product contains both a decongestant and an NSAID, the prescriber tailors the regimen to balance efficacy with safety, especially in individuals with underlying health conditions.

Safety during pregnancy or lactation has not been definitively established for the combination of pseudoephedrine and ibuprofen. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their obstetrician or primary care provider before using this medication.

To place an order, submit an enquiry on the Modafen Extra Grip product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

When taken separately, pseudoephedrine provides decongestant relief but does not address pain or fever, while ibuprofen reduces pain, fever and inflammation but does not clear nasal passages. Modafen Extra Grip combines both mechanisms in a single tablet, offering a more convenient option for patients who need simultaneous relief of congestion and associated aches or fever.

Store Modafen Extra Grip at ambient temperature below 25 °C (77 °F). Keep the tablets in their original blister pack or container, protect them from moisture, excessive heat and direct sunlight. Do not refrigerate or freeze the product, as temperature extremes can affect tablet integrity.

Modafen Extra Grip is taken orally with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless a healthcare professional advises otherwise. It is typically taken with or without food, but taking it with food may reduce stomach irritation for some individuals.

Serious risks include severe allergic reactions such as anaphylaxis, gastrointestinal bleeding, significant hypertension, renal impairment, Stevens‑Johnson syndrome and cardiovascular events like chest pain or arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, vomiting blood, sudden high blood pressure, or chest discomfort.

Modafen Extra Grip should be avoided by individuals with known hypersensitivity to pseudoephedrine, ibuprofen or any excipients, those with uncontrolled hypertension, severe coronary artery disease, recent myocardial infarction, active peptic ulcer disease, severe liver or kidney impairment, and by patients taking monoamine oxidase inhibitors. Consultation with a healthcare professional is essential before use in these populations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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