Product image of Modafinilo Tarbis (Modafinil) supplied by GNH India

Modafinilo Tarbis

Active Ingredient:
Modafinil
Origin:
EU

Modafinilo Tarbis (Modafinil)

Modafinil, the active ingredient in Modafinilo Tarbis, is a eugeroic presented as an oral tablet for oral use. It is prescribed to reduce excessive daytime sleepiness in conditions such as narcolepsy, obstructive sleep apnea, and shift work disorder.

GNH India supplies Modafinilo Tarbis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tarbis Farma, S.L.

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Indications & Clinical Uses

Modafinil acts on the central nervous system to promote wakefulness in disorders characterized by excessive daytime sleepiness.

  • Narcolepsy: improves alertness and reduces sudden sleep attacks.
  • Obstructive sleep apnea: lessens residual daytime sleepiness when used with primary therapy.
  • Shift work disorder: helps maintain wakefulness during scheduled work hours.

How It Works

  • Modafinil selectively inhibits dopamine reuptake, increasing extracellular dopamine concentrations, and concurrently activates orexin and histamine pathways in the hypothalamus. This combined effect enhances neuronal arousal and promotes sustained wakefulness without directly stimulating adrenergic receptors.

Side Effects

Modafinil may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Nausea: occasional gastrointestinal upset.
  • Insomnia: difficulty initiating or maintaining sleep.
  • Dry mouth: reduced salivation.
  • Anxiety: feelings of nervousness or tension.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reactions.
  • Psychiatric symptoms: hallucinations or mania.
  • Cardiovascular events: chest pain or arrhythmia.
  • Severe rash: widespread erythema.
  • Liver injury: elevated transaminases.
  • Allergic reaction: anaphylaxis or angioedema.

Precautions & Warnings

Before prescribing Modafinil, clinicians should consider several safety aspects.

  • Cardiovascular assessment: evaluate history of hypertension or heart disease.
  • Psychiatric evaluation: screen for prior psychosis or severe anxiety.
  • Hepatic function: monitor liver enzymes in patients with liver impairment.
  • Pregnancy and lactation: avoid use unless benefits outweigh potential risks.
  • Concomitant CNS stimulants: avoid additive stimulant effects.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Modafinil can affect the metabolism of several other medicines.

Major Interactions (Avoid)

  • CYP3A4 inhibitors (e.g., ketoconazole): may increase Modafinil levels.
  • CYP2C19 inhibitors (e.g., fluvoxamine): can raise plasma concentrations.
  • Hormonal contraceptives: reduced efficacy, consider alternative methods.

Moderate Interactions (Monitor Closely)

  • CYP2C9 substrates (e.g., warfarin): may require INR monitoring.
  • Antidepressants (e.g., SSRIs): watch for increased side‑effects.
  • Antiepileptic drugs (e.g., carbamazepine): may lower Modafinil effectiveness.

Frequently Asked Questions

Modafinilo Tarbis contains modafinil, which is indicated to improve wakefulness in patients with excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea, or shift work disorder. It helps reduce sudden sleep attacks and supports alertness during scheduled waking periods.

Modafinil works by selectively inhibiting the reuptake of dopamine, raising extracellular dopamine levels, and by activating orexin and histamine pathways in the brain. These actions together increase neuronal arousal and sustain wakefulness without directly stimulating adrenergic receptors.

The appropriate dose of Modafinilo Tarbis is determined by the prescribing clinician based on the individual’s medical condition, response, and tolerability. Dosage adjustments are made according to professional guidelines and patient-specific factors.

The safety of modafinil in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Modafinil differs from traditional stimulants such as amphetamines by having a lower risk of cardiovascular stimulation and abuse potential. Its mechanism focuses on dopamine reuptake inhibition and orexin activation, offering wakefulness with a generally milder side‑effect profile compared with older stimulants.

Store Modafinilo Tarbis at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat and direct sunlight to maintain potency.

Modafinilo Tarbis is taken orally, usually with a glass of water. It is typically administered once daily in the morning, but the exact timing and frequency are determined by the prescribing clinician based on the patient’s condition.

Serious adverse reactions, although rare, can include severe skin reactions such as Stevens‑Johnson syndrome, psychiatric events like hallucinations or mania, cardiovascular complications such as chest pain or arrhythmias, and significant liver injury. Patients should seek immediate medical attention if these occur.

Modafinilo Tarbis is contraindicated in individuals with known hypersensitivity to modafinil or any of its excipients. Caution is advised for patients with uncontrolled hypertension, serious cardiac disease, a history of psychiatric disorders, or those taking medications that strongly interact with modafinil.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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