Modolex (Calcium Dobesilate Monohydrate, Lidocaine Hydrochloride)

Calcium Dobesilate reduces capillary permeability and stabilises the endothelial lining of small blood vessels, which improves microcirculatory flow and limits oedema. This vasoprotective action helps to lessen the swelling and bleeding that occur in hemorrhoidal and fissure disease.

The dosage of Modolex is determined by the prescribing healthcare professional based on the severity of the condition, patient age and overall health. The prescriber will specify the amount, frequency and duration of rectal application appropriate for each individual case.

Safety data for Modolex in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To request Modolex, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with plain topical steroids or simple analgesics, Modolex combines a vasoprotective agent (calcium dobesilate) with a local anesthetic (lidocaine), offering both microcirculatory improvement and immediate pain relief. This dual mechanism can be advantageous in cases where swelling and pain are prominent.

Modolex should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from moisture and direct sunlight to maintain stability and potency throughout its shelf life.

Modolex is supplied as a rectal formulation. The prescribed amount is applied directly to the affected area using the provided applicator or as directed by the healthcare professional, ensuring gentle insertion and even distribution over the lesion.

The most serious adverse events include severe allergic reactions (anaphylaxis), persistent rectal bleeding, ulceration of the mucosa and systemic lidocaine toxicity, which can present with neurological or cardiac symptoms. Immediate medical attention is required if any of these occur.

Modolex should be avoided in patients with known hypersensitivity to calcium dobesilate, lidocaine or any formulation excipients, as well as in individuals with active rectal infections, severe inflammation, or those taking anticoagulant therapy without appropriate monitoring.