Product image of Modulair (Montelukast) supplied by GNH India

Modulair

Active Ingredient:
Montelukast
Origin:
EU

Modulair (Montelukast)

Montelukast, the active ingredient in Modulair, is a leukotriene receptor antagonist presented as an oral tablet (strength not specified) for oral administration. It helps control asthma, prevents exercise‑induced bronchoconstriction, and relieves symptoms of allergic rhinitis in both adults and children.

GNH India supplies Modulair as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide under strict quality standards and regulatory oversight. The company ensures traceability, proper packaging, and compliance with EU marketing authorisation requirements for each batch.

Manufacturer / TM Owner

Elpen Pharmaceutical Co. Inc.

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Indications & Clinical Uses

Modulair (montelukast) is a leukotriene receptor antagonist used to treat conditions mediated by cysteinyl leukotrienes.

  • Asthma: reduces frequency of wheezing episodes and improves lung function.
  • Exercise‑induced bronchoconstriction: prevents narrowing of the airways during physical activity.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonising this receptor, it inhibits leukotriene‑mediated bronchoconstriction, vascular permeability, and eosinophil recruitment, thereby reducing airway inflammation and hyper‑responsiveness associated with asthma and allergic rhinitis.

Side Effects

Adverse reactions may occur with any medication and should be monitored.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as rash or angioedema
  • Mood changes including depression or suicidal thoughts
  • Liver enzyme elevations

Precautions & Warnings

Before prescribing Modulair, clinicians should consider several safety aspects.

  • Assess asthma control: ensure patient is on appropriate baseline therapy.
  • Monitor for neuropsychiatric events: watch for mood changes or suicidal ideation.
  • Use with caution in hepatic impairment: dose adjustment may be required.
  • Avoid in patients with known hypersensitivity to montelukast or any tablet excipients.
  • Review concomitant medications for potential interactions.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Phenobarbital: enzyme induction reduces montelukast exposure.
  • Rifampin: strong inducer of metabolism, decreasing effectiveness.
  • Ketoconazole: inhibits metabolism, potentially increasing systemic levels.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR; monitor coagulation parameters.
  • Beta‑agonists: may diminish bronchodilator response; assess clinical effect.

Frequently Asked Questions

Modulair contains montelukast, which is indicated for the long‑term management of asthma, the prevention of exercise‑induced bronchoconstriction, and the relief of symptoms associated with allergic rhinitis such as nasal congestion, sneezing and itchy eyes.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction and reduces airway inflammation, helping to keep the airways open and less reactive.

The appropriate dose of Modulair is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety data for montelukast in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing Modulair to pregnant or nursing individuals, and discuss alternative options when appropriate.

To request Modulair, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Modulair (montelukast) belongs to the leukotriene receptor antagonist class, which works by a different mechanism than inhaled corticosteroids or beta‑agonists. It is often used as an add‑on therapy for patients who need additional control or who experience exercise‑induced symptoms, offering an oral alternative to inhaled medications.

Modulair should be stored at room temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture and direct sunlight to maintain stability and potency throughout the shelf life.

Modulair is taken orally, usually as a single tablet each day. It can be swallowed with or without food, according to the prescriber’s instructions. Consistency in the time of day helps maintain steady drug levels.

Serious adverse events, although rare, include severe allergic reactions such as rash or angioedema, mood changes including depression or suicidal thoughts, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience any of these symptoms.

Modulair is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. It should also be used with caution in patients with severe hepatic impairment and those taking medications that strongly affect its metabolism.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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