Product image of Mokast (Montelukast) supplied by GNH India

Mokast

Active Ingredient:
Montelukast
Origin:
EU

Mokast (Montelukast)

Montelukast, the active ingredient in Mokast, is a leukotriene receptor antagonist presented as an oral tablet for oral administration. It is used to manage chronic asthma, seasonal allergic rhinitis, and exercise‑induced bronchoconstriction in both adult and pediatric patients, helping to reduce airway inflammation and improve breathing.

GNH India supplies Mokast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across EU and other global markets. The company adheres to stringent quality standards and provides regulatory documentation for importers.

Manufacturer / TM Owner

Rafarm Sa.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Montelukast acts on leukotriene pathways to treat several respiratory and allergic conditions.

  • Asthma: improves control of chronic symptoms and reduces frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by seasonal allergens.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor type 1 (CysLT1) on airway smooth‑muscle cells, mast cells and eosinophils. By antagonizing this receptor, it inhibits the actions of leukotriene D4 and related mediators that cause bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment, thereby reducing airway inflammation and hyper‑responsiveness. The effect is sustained throughout the dosing interval, contributing to long‑term control of symptoms.

Side Effects

Montelukast may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Upper respiratory tract infection: nasopharyngitis or common cold symptoms.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Cough: occasional dry cough.

Serious or Rare Side Effects

  • Allergic reactions: rash, urticaria, or angioedema requiring medical attention.
  • Neuropsychiatric events: mood changes, agitation, or rare suicidal thoughts.
  • Hepatic dysfunction: abnormal liver enzymes or hepatitis.

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several precautionary measures to ensure safe use.

  • Assess patient history: review asthma control level and prior leukotriene antagonist response.
  • Monitor for neuropsychiatric symptoms: observe mood or behavior changes during therapy.
  • Use cautiously in hepatic impairment: adjust or monitor liver function tests as needed.
  • Avoid in patients with known hypersensitivity to Montelukast or excipients.
  • Pregnancy and lactation: evaluate risk‑benefit; limited data available.
  • Store at ambient temperature below 25°C: keep in original container, protect from moisture and light.

Avoid Interactions

Montelukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital, carbamazepine, rifampin: strong enzyme inducers that may reduce Montelukast plasma levels.
  • Ritonavir or other potent CYP3A4 inhibitors: may increase exposure, potentially enhancing adverse effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of anticoagulant effect; monitor INR.
  • Theophylline: concurrent use may require monitoring of respiratory status.
  • Antidepressants (e.g., fluoxetine): may modestly increase risk of neuropsychiatric events.

Frequently Asked Questions

Mokast contains the active ingredient Montelukast and is prescribed to help control chronic asthma, relieve symptoms of seasonal allergic rhinitis, and prevent exercise‑induced bronchoconstriction. It works by reducing airway inflammation and narrowing, thereby improving breathing in both adults and children.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes from binding. This inhibition stops the cascade that leads to bronchoconstriction, mucus production, and inflammation, resulting in better airway patency and reduced allergic symptoms.

The appropriate dose of Mokast is determined by the prescribing clinician based on the patient’s age, condition severity, and response to therapy. Dosage regimens may differ for asthma, allergic rhinitis, or exercise‑induced bronchoconstriction, and should follow the prescriber’s instructions.

Safety data for Montelukast in pregnancy and lactation are limited. Clinicians should weigh potential benefits against possible risks and consider alternative treatments when appropriate. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To order Mokast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mokast belongs to the leukotriene receptor antagonist class, which differs from inhaled corticosteroids and bronchodilators. It is taken orally once daily and is particularly useful for patients who need additional control beyond inhaled therapy or who experience exercise‑related bronchoconstriction. Choice of therapy depends on individual disease patterns and physician assessment.

Mokast tablets should be stored at ambient temperature below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discolored.

Mokast is administered orally, usually as a single tablet taken with or without food once daily, as directed by the prescriber. Swallow the tablet whole with water; do not crush or chew unless specifically instructed.

Serious adverse events linked to Montelukast include allergic reactions such as rash, urticaria or angioedema, neuropsychiatric effects like mood changes or rare suicidal thoughts, and liver function abnormalities. Patients should seek immediate medical attention if they notice any of these symptoms.

Mokast should be avoided in individuals with known hypersensitivity to Montelukast or any of its excipients. Caution is also advised for patients with severe hepatic impairment, and it is not recommended for use in children under the age approved for the specific indication without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.