Product image of Moksifloksacin Stada (Moxifloxacin) supplied by GNH India

Moksifloksacin Stada

Active Ingredient:
Moxifloxacin
Origin:
EU

Moksifloksacin Stada (Moxifloxacin)

Moxifloxacin, the active ingredient in Moksifloksacin Stada, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a variety of bacterial infections, including respiratory, sinus, skin and intra‑abdominal infections, in adult and pediatric patients when prescribed by a qualified healthcare professional.

GNH India supplies Moksifloksacin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company consistently adheres to stringent quality standards and provides regulatory‑approved products to meet global demand throughout.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Moxifloxacin is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria across several organ systems.

  • Community-acquired bacterial pneumonia: provides effective eradication of the pathogen, improving respiratory function and reducing fever.
  • Acute bacterial sinusitis: alleviates sinus inflammation and clears infection, leading to symptom relief.
  • Acute bacterial exacerbation of chronic bronchitis: reduces bacterial load, helping to restore normal airway clearance.
  • Skin and skin structure infections: combats Gram‑positive and Gram‑negative organisms, promoting wound healing.
  • Intra-abdominal infections: targets mixed bacterial flora, supporting recovery after surgical or medical management.

How It Works

  • Moxifloxacin exerts its antibacterial activity by binding to bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA supercoiling and replication. Inhibition of these enzymes prevents the unwinding and resealing of DNA strands during replication and transcription, leading to bacterial cell death. The drug displays concentration‑dependent killing and a post‑antibiotic effect against a broad spectrum of Gram‑positive, Gram‑negative and atypical pathogens.

Side Effects

Moxifloxacin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Rash

Serious or Rare Side Effects

  • Tendon rupture or inflammation
  • QT interval prolongation leading to arrhythmia
  • Severe allergic reactions such as anaphylaxis
  • Clostridioides difficile‑associated colitis
  • Peripheral neuropathy
  • Hepatic enzyme elevation

Precautions & Warnings

When prescribing or dispensing Moksifloksacin Stada, consider the following precautions:

  • Assess renal and hepatic function: adjust therapy if impairment is present.
  • Avoid use in patients with a history of tendon disorders: risk of tendon rupture is increased.
  • Monitor cardiac status: watch for QT prolongation, especially with other QT‑prolonging agents.
  • Use with caution in pregnancy and breastfeeding: safety data are limited.
  • Counsel patients to avoid concomitant NSAIDs or corticosteroids when possible: may heighten tendon injury risk.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and light.

Avoid Interactions

Moksifloksacin Stada can interact with several medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Antacids or supplements containing aluminum, magnesium, calcium, or iron: markedly reduce oral absorption.
  • Warfarin: may potentiate anticoagulant effect and increase INR.
  • Theophylline: increased plasma concentrations leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: combined use raises risk of tendon rupture.
  • Other QT‑prolonging drugs (e.g., macrolides, fluoroquinolones): additive effect on cardiac rhythm.
  • Diabetes medications (e.g., insulin, sulfonylureas): may affect glycemic control.

Frequently Asked Questions

Moksifloksacin Stada contains moxifloxacin, a fluoroquinolone antibiotic indicated for the treatment of several bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and intra‑abdominal infections caused by susceptible organisms.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. By blocking these targets, the drug prevents bacterial DNA from unwinding and resealing, leading to bacterial cell death and eradication of the infection.

The prescribed dose of Moksifloksacin Stada is determined by the treating physician based on the type and severity of the infection, patient age, renal and hepatic function, and other clinical considerations. Dosage regimens are individualized and should follow the prescriber's instructions.

Safety data for moxifloxacin in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Moxifloxacin offers a broader spectrum of activity against atypical and Gram‑positive pathogens compared with some older fluoroquinolones such as ciprofloxacin. It also provides once‑daily dosing for many indications, which can improve patient adherence. However, safety considerations such as tendon toxicity and QT prolongation are similar across the class, so risk‑benefit assessment remains essential.

Moksifloksacin Stada should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and direct light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

The medication is taken orally, usually as a tablet, with a full glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their prescriber to ensure optimal absorption.

Serious adverse events include tendon rupture or inflammation, QT interval prolongation that may lead to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, peripheral neuropathy, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience sudden joint pain, palpitations, severe rash, or persistent diarrhea.

Moksifloksacin Stada is contraindicated in individuals with a known hypersensitivity to moxifloxacin or other fluoroquinolones. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use, those with uncontrolled arrhythmias, and, unless clearly justified, in pregnant or breastfeeding women due to limited safety data.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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