Product image of Molaxole (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Molaxole

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Molaxole (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, and Macrogol 3350, the active ingredients in Molaxole, are an osmotic laxative presented as an oral powder for oral use. It is used to relieve constipation and to prepare the bowel for diagnostic procedures in adults.

GNH India supplies Molaxole as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Molaxole is used as an osmotic laxative to manage conditions related to bowel motility and preparation.

  • Constipation: provides gentle, water‑based stool softening to facilitate regular bowel movements.
  • Bowel preparation for colonoscopy: clears intestinal contents to improve visualization during endoscopic procedures.
  • Chronic idiopathic constipation: supports long‑term bowel regularity in patients with persistent constipation.

How It Works

  • Molaxole works by creating an osmotic gradient in the intestinal lumen; macrogol 3350 retains water, while the sodium, potassium, and chloride salts increase the osmotic load. This draws fluid into the bowel, softening stool and stimulating peristalsis, which promotes bowel evacuation without significant systemic absorption.

Side Effects

Molaxole may be associated with several adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Abdominal bloating: mild distension of the abdomen.
  • Nausea: feeling of queasiness.
  • Flatulence: increased intestinal gas.
  • Diarrhea: loose, watery stools.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Dehydration: excessive loss of body fluids.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.

Precautions & Warnings

When using Molaxole, consider the following precautions to minimize risk.

  • Renal impairment: assess kidney function before use.
  • Electrolyte disorders: monitor serum sodium and potassium levels.
  • Gastrointestinal obstruction: avoid use in patients with known bowel blockage.
  • Pregnancy and lactation: use only if clearly needed after risk assessment.
  • Concomitant laxatives: avoid combining with other osmotic agents.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Molaxole can interact with other medicines; interactions are grouped by clinical significance.

Major Interactions (Avoid)

  • Loop diuretics: may exacerbate electrolyte loss.
  • Mineral supplements containing sodium or potassium: can cause excessive electrolyte shifts.
  • Anticholinergic agents: may reduce laxative effectiveness.

Moderate Interactions (Monitor Closely)

  • Antihypertensive drugs: monitor blood pressure due to possible fluid shifts.
  • NSAIDs: watch for renal function changes.
  • Oral rehydration solutions: adjust dosing to maintain electrolyte balance.

Frequently Asked Questions

Molaxole is an oral osmotic laxative indicated for the relief of occasional constipation and for bowel cleansing prior to diagnostic procedures such as colonoscopy. It works by increasing the water content of the stool, facilitating easier passage and improving intestinal clearance.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is poorly absorbed in the gut. It binds water molecules, creating an osmotic gradient that retains fluid in the intestinal lumen. The resulting increase in stool volume softens the stool and stimulates peristalsis, promoting bowel movements.

The specific dose of Molaxole is determined by the prescribing healthcare professional based on the patient’s condition, age, and response to therapy. Dosage instructions are provided on the product label and should be followed exactly as directed by the prescriber.

Molaxole should be used during pregnancy or lactation only if clearly needed and after a risk‑benefit assessment by the treating physician. Limited data are available, so clinicians weigh potential benefits for constipation relief against any possible risks to the fetus or infant.

To order Molaxole, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Molaxole’s osmotic mechanism provides gentler, water‑based stool softening with a lower risk of cramping. Unlike some saline laxatives, it contains balanced electrolytes, reducing the likelihood of significant electrolyte disturbances when used as directed.

Molaxole should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid exposure to extreme heat or humidity.

Molaxole is taken orally, usually dissolved in a measured amount of water or another suitable liquid as instructed by the prescriber. The solution should be consumed promptly after preparation, and patients are advised to follow any fluid intake recommendations to support the laxative effect.

Serious risks, though rare, include severe electrolyte imbalance, dehydration, and allergic reactions such as rash, swelling or breathing difficulty. Patients experiencing these symptoms should seek immediate medical attention, and clinicians should monitor electrolyte levels in high‑risk individuals.

Molaxole is contraindicated in patients with known or suspected bowel obstruction, perforation, or severe inflammatory bowel disease. It should also be avoided in individuals with uncontrolled electrolyte disorders or severe renal impairment unless closely supervised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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