Product image of Mollifeye (Chloramphenicol) supplied by GNH India

Mollifeye

Active Ingredient:
Chloramphenicol
Origin:
EU

Mollifeye (Chloramphenicol)

Chloramphenicol, the active ingredient in Mollifeye, is an antibiotic presented as an ophthalmic preparation for ocular use. It is employed to treat bacterial eye infections by inhibiting the growth of susceptible microorganisms in the conjunctiva, cornea, and surrounding ocular tissues.

GNH India supplies Mollifeye as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with the product sourced from EU‑approved manufacturers. Our distribution network ensures consistent quality and regulatory compliance across regions.

Manufacturer / TM Owner

Aspire Pharma Limited

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Indications & Clinical Uses

Mollifeye (chloramphenicol) is used to treat bacterial infections of the eye and related ocular tissues.

  • Bacterial conjunctivitis: reduces bacterial load and alleviates inflammation of the conjunctiva.
  • Bacterial keratitis: eradicates pathogenic bacteria in the cornea, promoting healing and preventing scarring.
  • Blepharitis: controls bacterial overgrowth on the eyelid margins, reducing redness and irritation.

How It Works

  • Chloramphenicol exerts its antibacterial effect by binding to the 50S subunit of bacterial ribosomes, thereby inhibiting the peptidyl transferase activity essential for protein synthesis. This blockade prevents the formation of peptide bonds, halting bacterial growth and replication. The action is bacteriostatic against most susceptible organisms and is effective across a broad spectrum of Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Ophthalmic chloramphenicol may cause local and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Stinging or burning sensation on application.
  • Transient blurred vision.
  • Mild conjunctival redness.

Serious or Rare Side Effects

  • Allergic contact dermatitis with swelling.
  • Corneal epithelial toxicity or ulceration.
  • Systemic bone marrow suppression (aplastic anemia) in rare cases.

Precautions & Warnings

When using Mollifeye, several precautions should be observed to ensure safety and maintain product efficacy.

  • Allergy assessment: avoid use in patients with known hypersensitivity to chloramphenicol or any formulation components.
  • Contact lens use: discontinue lens wear during treatment and resume only after therapy completion.
  • Duration of therapy: limit use to the prescribed period to reduce risk of resistance and toxicity.
  • Systemic exposure: monitor patients with extensive ocular surface disease for signs of systemic absorption.
  • Pregnancy and lactation: consider potential risks and consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from light and moisture, and do not freeze.

Avoid Interactions

Chloramphenicol ophthalmic can interact with certain systemic and topical agents; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Systemic chloramphenicol: concurrent use may increase risk of bone marrow suppression.
  • Anticoagulants (e.g., warfarin): may enhance anticoagulant effect, increasing bleeding risk.
  • Live vaccines: systemic absorption could theoretically diminish vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Other ophthalmic antibiotics: may cause additive ocular irritation.
  • Non‑steroidal anti‑inflammatory eye drops: monitor for increased local inflammation.
  • Topical corticosteroids: assess for delayed wound healing when combined.

Frequently Asked Questions

Mollifeye contains chloramphenicol and is indicated for the treatment of bacterial eye infections such as conjunctivitis, keratitis and blepharitis. It works by inhibiting bacterial growth on the ocular surface, helping to relieve symptoms and prevent complications.

Chloramphenicol binds to the 50S ribosomal subunit of susceptible bacteria, blocking the peptidyl transferase step of protein synthesis. This stops the formation of new proteins, halting bacterial replication and allowing the immune system to clear the infection.

The dosing regimen for Mollifeye is determined by the prescribing clinician based on the type and severity of the infection, patient age and ocular condition. Typical regimens involve one to several drops per eye at prescribed intervals, but exact instructions must come from a qualified healthcare professional.

Safety data for ophthalmic chloramphenicol during pregnancy and lactation are limited. Healthcare providers should weigh potential benefits against possible risks and consider alternative treatments when appropriate. Pregnant or nursing patients should discuss use with their physician.

To request Mollifeye, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mollifeye (chloramphenicol) offers a broad spectrum of activity against many Gram‑positive and Gram‑negative ocular pathogens and is bacteriostatic. Compared with fluoroquinolone eye drops, it may have a lower risk of resistance development but carries rare systemic toxicity concerns, making patient selection important.

Mollifeye should be stored at room temperature, protected from direct light and moisture. Keep the container tightly closed and retain it in its original packaging until use. Do not freeze the product, and discard any solution that appears discolored or contaminated.

Mollifeye is applied topically to the eye as directed by the prescriber. Typically, the recommended number of drops is placed into the conjunctival sac of the affected eye(s) at the prescribed interval, avoiding contact with the tip of the bottle to maintain sterility.

Serious adverse events, although rare, include allergic contact dermatitis with swelling, corneal epithelial toxicity that can lead to ulceration, and systemic bone‑marrow suppression such as aplastic anemia. Patients should be instructed to seek immediate medical attention if they experience severe eye pain, vision changes or systemic symptoms.

Mollifeye is contraindicated in individuals with a known hypersensitivity to chloramphenicol or any excipients in the formulation. It should also be avoided in patients with pre‑existing severe bone‑marrow disorders and used with caution in pregnant or nursing women until a risk‑benefit assessment is performed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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