Product image of Mollisupradin (Bromhexine Hydrochloride, Ephedrine Hydrochloride) supplied by GNH India

Mollisupradin

Active Ingredient:
Bromhexine Hydrochloride, Ephedrine Hydrochloride
Origin:
EU

Mollisupradin (Bromhexine Hydrochloride, Ephedrine Hydrochloride)

Bromhexine Hydrochloride and Ephedrine Hydrochloride, the active ingredients in Mollisupradin, are a mucolytic and sympathomimetic presented as an oral formulation for systemic use. They help relieve cough, bronchial congestion and nasal congestion associated with acute respiratory infections in adults.

GNH India supplies Mollisupradin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Unimedic Pharma Ab

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Indications & Clinical Uses

Mollisupradin acts on the respiratory tract to improve clearance of secretions and reduce congestion.

  • Cough associated with acute respiratory infections: reduces mucus viscosity and eases expectoration.
  • Bronchial congestion: facilitates clearance of bronchial secretions.
  • Nasal congestion: provides decongestion through adrenergic stimulation.

How It Works

  • Bromhexine Hydrochloride disrupts the structure of mucus glycoproteins, lowering viscosity and promoting mucociliary clearance. Ephedrine Hydrochloride stimulates both alpha‑ and beta‑adrenergic receptors, producing bronchodilation, increased airway airflow and vasoconstriction of nasal mucosa, which together alleviate bronchial and nasal congestion.

Side Effects

Mollisupradin may cause a range of adverse reactions.

Common Side Effects

  • Nausea
  • Dizziness
  • Headache
  • Insomnia
  • Dry mouth
  • Palpitations

Serious or Rare Side Effects

  • Arrhythmia
  • Hypertension
  • Severe allergic reaction (anaphylaxis)
  • Seizures
  • Myocardial infarction
  • Severe hypotension

Precautions & Warnings

Before prescribing Mollisupradin, consider the following safety measures.

  • Assess cardiovascular status: monitor blood pressure and heart rate before initiating therapy.
  • Avoid use in patients with uncontrolled hypertension: risk of further elevation.
  • Caution in patients with thyroid disorders: ephedrine may exacerbate symptoms.
  • Do not combine with monoamine oxidase inhibitors: risk of hypertensive crisis.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Mollisupradin can interact with several drug classes; monitoring is essential.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension.
  • Beta‑blockers: may reduce bronchodilator effect of ephedrine.
  • Tricyclic antidepressants: increased cardiovascular side effects.
  • Diuretics: may potentiate hypokalemia.
  • Alkaloid‑containing foods: additive sympathomimetic effects.

Moderate Interactions (Monitor Closely)

  • Caffeine: may increase stimulant effects.
  • Theophylline: additive bronchodilation may cause tachycardia.
  • Antihypertensives: possible attenuation of blood pressure control.
  • Anticholinergics: may increase dry mouth.
  • Anticoagulants: monitor for bleeding risk due to possible platelet effects.

Frequently Asked Questions

Mollisupradin is used to treat cough, bronchial congestion and nasal congestion that occur with acute respiratory infections. It combines a mucolytic to thin mucus and a sympathomimetic to open airways and reduce nasal swelling, helping patients breathe more comfortably.

Bromhexine Hydrochloride acts on mucus glycoproteins, breaking down their structure and lowering viscosity. This makes the mucus less thick, allowing cilia in the respiratory tract to move it more efficiently toward the throat for expectoration.

The appropriate dose of Mollisupradin is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of symptoms and any co‑existing medical conditions. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Safety in pregnancy and lactation has not been fully established. The product should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike single‑ingredient cough suppressants, Mollisupradin combines a mucolytic (bromhexine) with a sympathomimetic (ephedrine). This dual action both thins mucus and opens airways, offering a broader approach for patients with both productive cough and nasal congestion.

Mollisupradin should be stored at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain product stability.

Mollisupradin is taken orally, usually with a glass of water. The exact administration schedule—such as frequency and timing relative to meals—should follow the prescribing clinician’s directions.

Serious risks include arrhythmias, severe hypertension, allergic reactions such as anaphylaxis, seizures and myocardial infarction. Patients should seek immediate medical attention if they experience chest pain, rapid heartbeat, severe headache, difficulty breathing or signs of an allergic reaction.

Mollisupradin is contraindicated in individuals with known hypersensitivity to bromhexine, ephedrine or any excipients, as well as patients taking monoamine oxidase inhibitors. Caution is also advised for those with uncontrolled hypertension, certain thyroid disorders, or severe cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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