Product image of Momcort (Mometasone Furoate) supplied by GNH India

Momcort

Active Ingredient:
Mometasone Furoate
Origin:
EU

Momcort (Mometasone Furoate)

Mometasone furoate, the active ingredient in Momcort, is a corticosteroid presented as a nasal spray for nasal administration. It is indicated for the relief of nasal symptoms associated with allergic rhinitis in both adults and pediatric patients, reducing inflammation and congestion.

GNH India supplies Momcort as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing consistent quality and regulatory compliance for global distribution. The product complies with European Union marketing authorisation standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Momcort (mometasone furoate) is a nasal corticosteroid used to manage inflammatory conditions of the nasal passages.

  • Allergic rhinitis: reduces nasal congestion, itching, and sneezing.
  • Seasonal allergic rhinitis: provides symptom relief during pollen exposure.
  • Perennial allergic rhinitis: controls year‑round nasal inflammation.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal mucosal cells, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and adhesion molecules, leading to reduced vascular permeability, edema, and inflammatory cell infiltration in the nasal mucosa. The anti‑inflammatory effect is localized due to low systemic absorption after intranasal delivery.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning.
  • Headache.
  • Epistaxis (nosebleed).
  • Sore throat.
  • Altered taste.
  • Cough.

Serious or Rare Side Effects

  • Nasal septal perforation.
  • Adrenal suppression.
  • Cataracts or increased intra‑ocular pressure.
  • Severe allergic reaction (anaphylaxis).
  • Opportunistic fungal infection of the nasal passages.

Precautions & Warnings

Before prescribing Momcort, clinicians should consider several precautionary measures to ensure safe use.

  • Assess for nasal infections: avoid use in active bacterial, fungal, or viral sinusitis.
  • Monitor in patients with glaucoma or cataracts: may exacerbate intra‑ocular pressure.
  • Caution in children: use the lowest effective dose and limit duration.
  • Evaluate systemic corticosteroid exposure: avoid concurrent high‑dose systemic steroids.
  • Avoid abrupt discontinuation: taper if long‑term therapy is required.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate nasal spray can interact with certain medications, affecting either its efficacy or safety profile.

Major Interactions (Avoid)

  • Concomitant strong CYP3A4 inhibitors may increase systemic exposure.
  • Use with systemic corticosteroids can lead to additive immunosuppression.
  • Concurrent immunosuppressants may raise the risk of infection.

Moderate Interactions (Monitor Closely)

  • Intranasal decongestants may increase local irritation.
  • Antihistamines can mask symptoms, potentially delaying detection of adverse effects.

Frequently Asked Questions

Momcort is a prescription nasal spray containing mometasone furoate, a corticosteroid indicated for the treatment of allergic rhinitis. It helps relieve nasal congestion, itching, sneezing, and rhinorrhoea by reducing inflammation in the nasal passages.

Mometasone furoate acts as a glucocorticoid receptor agonist. After binding to intracellular receptors in nasal mucosal cells, it modulates gene expression to suppress pro‑inflammatory cytokines, chemokines, and adhesion molecules, thereby decreasing edema and inflammatory cell infiltration.

The dosage of Momcort is individualized by the prescribing clinician. Typically, patients are instructed to prime the spray and then administer a specific number of sprays per nostril once or twice daily, following the prescriber’s directions.

Safety data for mometasone furoate nasal spray in pregnancy and lactation are limited. Healthcare providers should weigh potential benefits against risks and discuss use with a qualified professional before initiating therapy in pregnant or nursing individuals.

To order Momcort, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Momcort (mometasone furoate) is a high‑potency intranasal corticosteroid with low systemic bioavailability, offering effective symptom control with a favorable safety profile. Compared with older agents such as beclomethasone, it often requires fewer daily sprays and may have a reduced risk of systemic side effects.

Momcort should be stored at room temperature, below 25 °C, in its original packaging. Protect the spray from moisture and direct sunlight. Do not freeze the product, and keep the nozzle clean to maintain proper dosing.

Before first use, prime the spray by actuating it a few times away from the face. Then, tilt the head slightly forward, insert the tip into one nostril, close the opposite nostril, and gently inhale while pressing the pump. Repeat for the other nostril as directed by the prescriber.

Serious risks, although rare, include nasal septal perforation, adrenal suppression, cataracts or increased intra‑ocular pressure, severe allergic reactions such as anaphylaxis, and opportunistic fungal infections of the nasal mucosa. Patients should report any unusual symptoms promptly.

Momcort is contraindicated in individuals with known hypersensitivity to mometasone furoate or any component of the formulation, and in patients with active untreated bacterial, fungal, or viral infections of the nasal passages. Caution is advised for patients with uncontrolled glaucoma, cataracts, or systemic immunosuppression.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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