Product image of Momecort (Mometasone Furoate Monohydrate) supplied by GNH India

Momecort

Active Ingredient:
Mometasone Furoate Monohydrate
Origin:
EU

Momecort (Mometasone Furoate Monohydrate)

Mometasone furoate monohydrate, the active ingredient in Momecort, is a corticosteroid presented as a nasal spray for intranasal use. It is indicated for the management of allergic rhinitis and nasal polyps in appropriate patient populations.
GNH India supplies Momecort as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farto S.R.L. Farmaco Biochimico Toscano

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Indications & Clinical Uses

Momecort is a nasal corticosteroid that reduces inflammation in the upper airway.

  • Allergic rhinitis: relieves nasal congestion, itching and sneezing caused by allergic inflammation.
  • Nasal polyps: helps shrink polyps and improves nasal airflow.
  • Seasonal allergic rhinitis: controls symptoms during pollen seasons by decreasing mucosal swelling.

How It Works

  • Mometasone furoate monohydrate binds to intracellular glucocorticoid receptors in nasal mucosal cells, forming a complex that translocates to the nucleus and inhibits transcription of pro‑inflammatory cytokines, chemokines and adhesion molecules. This suppresses the inflammatory cascade, reduces edema, and restores normal nasal airflow.

Side Effects

Momecort may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning sensation
  • Dryness of the nasal mucosa
  • Epistaxis (nosebleeds)
  • Headache
  • Altered taste or bitter taste
  • Throat irritation or cough

Serious or Rare Side Effects

  • Nasal septal perforation
  • Severe allergic reaction (anaphylaxis)
  • Vision changes such as cataracts or glaucoma
  • Adrenal suppression with prolonged high‑dose use
  • Opportunistic fungal infection of the nasal passages

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess for active nasal infection: avoid use in untreated bacterial or fungal sinusitis.
  • Avoid concurrent use with other intranasal corticosteroids to prevent excess systemic exposure.
  • Monitor growth in pediatric patients during long‑term treatment.
  • Use with caution in patients with glaucoma or cataracts.
  • Do not use in individuals with known hypersensitivity to mometasone or excipients.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Momecort can interact with other medicines that affect corticosteroid metabolism or systemic exposure.

Major Interactions (Avoid)

  • Systemic corticosteroids: increase risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir): may raise local drug levels.
  • Antifungal azoles used systemically: potential for enhanced steroid activity.

Moderate Interactions (Monitor Closely)

  • Moderate CYP3A4 inhibitors (e.g., erythromycin, fluconazole): may modestly increase exposure.
  • Immunosuppressants (e.g., cyclosporine): monitor for additive immunosuppression.
  • Nasal decongestants: may mask underlying infection, use with clinical judgment.

Frequently Asked Questions

Momecort is indicated for the treatment of allergic rhinitis, including seasonal and perennial forms, and for the management of nasal polyps. It works by reducing inflammation within the nasal passages, helping to relieve congestion, sneezing, itching, and improving airflow.

Mometasone furoate monohydrate binds to glucocorticoid receptors in nasal mucosal cells, inhibiting the transcription of inflammatory cytokines and mediators. This suppression of the inflammatory response decreases swelling, mucus production, and irritation, leading to symptom relief.

The specific dose and frequency of Momecort are determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Patients should follow the prescriber’s instructions and the product label.

Safety data for mometasone furoate monohydrate in pregnancy and lactation are limited. The prescriber should weigh the potential benefits against any possible risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Momecort (mometasone furoate) is a high‑potency intranasal corticosteroid with a favorable safety profile when used at recommended doses. Compared with lower‑potency agents such as fluticasone, mometasone often provides comparable or greater symptom control with once‑daily dosing, but individual response may vary.

Momecort should be stored at room temperature, below 25 °C (77 °F). Keep the spray in its original packaging, protect it from moisture, direct sunlight and excessive heat to maintain potency and stability.

Momecort is administered as a nasal spray. The patient gently shakes the bottle, tilts the head slightly forward, inserts the nozzle into one nostril, and sprays the prescribed number of sprays while breathing in gently. The process is repeated in the other nostril if directed by the prescriber.

Serious but rare risks include nasal septal perforation, severe allergic reactions such as anaphylaxis, adrenal suppression with prolonged high‑dose use, and opportunistic fungal infections of the nasal passages. Patients should report any unusual bleeding, persistent irritation, or systemic symptoms to their healthcare provider promptly.

Momecort should be avoided in individuals with known hypersensitivity to mometasone furoate or any of the formulation excipients, and in patients with untreated bacterial, viral, or fungal nasal infections. It is also contraindicated in those who are already using another intranasal corticosteroid without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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