Momen (Benzydamine Hydrochloride)

Benzydamine Hydrochloride is a topical NSAID used to manage inflammation and pain in the oral cavity and skin.

• Oral mucositis: reduces pain and inflammation of chemotherapy‑ or radiotherapy‑induced lesions.
• Sore throat: alleviates discomfort and swelling of the pharyngeal mucosa.
• Oral ulcer: promotes symptomatic relief and faster healing of aphthous lesions.
• Dermatitis: diminishes local inflammation and itching of mild skin irritation.
• Local skin inflammation: provides analgesic and anti‑inflammatory action on minor cuts, abrasions or irritant dermatitis.

• Benzydamine Hydrochloride exerts its local anti‑inflammatory, analgesic and anesthetic actions by inhibiting the release of pro‑inflammatory cytokines (such as IL‑1β and TNF‑α) and stabilising cell membranes. The compound also interferes with the synthesis of prostaglandins and leukotrienes, reducing peripheral sensitisation of nociceptors and limiting the inflammatory cascade at the site of application.

Benzydamine Hydrochloride is generally well tolerated when applied topically, but some adverse reactions may occur.

Common Side Effects

• Burning sensation at the application site
• Stinging or tingling feeling
• Mild itching or pruritus
• Transient dryness of the mucosa
• Slight taste alteration
• Mild erythema or redness

Serious or Rare Side Effects

• Allergic contact dermatitis
• Angioedema involving lips or face
• Severe urticaria or hives
• Anaphylactic reaction requiring emergency care
• Systemic hypersensitivity with fever
• Persistent ulceration or necrosis at the site

When using Momen, consider the following safety measures.

• Use only on intact mucosal surfaces: avoid application to broken or ulcerated tissue unless directed by a clinician.
• Limit duration of continuous use: prolonged exposure may increase irritation risk.
• Avoid contact with eyes: accidental exposure can cause significant discomfort.
• Discontinue immediately if signs of allergic reaction appear, such as rash or swelling.
• Not recommended for children under the age specified by the prescriber due to limited safety data.
• Store at room temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Benzydamine Hydrochloride may interact with other agents that affect inflammation or bleeding.

Major Interactions (Avoid)

• Concurrent use of other topical NSAIDs: may increase local irritation or systemic absorption.
• Systemic anticoagulants (e.g., warfarin, direct oral anticoagulants): heightened risk of mucosal bleeding.
• Strong corticosteroid preparations applied to the same area: can mask signs of infection.

Moderate Interactions (Monitor Closely)

• Oral NSAIDs taken simultaneously: monitor for additive gastrointestinal irritation.
• Antihistamines or mast‑cell stabilisers: may alter the perception of local itching.
• Alcohol‑containing mouthwashes: could increase burning sensation.