Product image of Momentkid Prima Infanzia (Ibuprofen) supplied by GNH India

Momentkid Prima Infanzia

Active Ingredient:
Ibuprofen
Origin:
EU

Momentkid Prima Infanzia (Ibuprofen)

Ibuprofen, the active ingredient in Momentkid Prima Infanzia, is a nonsteroidal anti-inflammatory drug presented as a rectal formulation for rectal use. It is employed to relieve mild to moderate pain, lower fever, and mitigate inflammatory discomfort in children, offering a convenient alternative when oral administration is not feasible.

GNH India supplies Momentkid Prima Infanzia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with the product sourced from the European Union market and meeting applicable quality standards.

Manufacturer / TM Owner

Angelini Pharma S.P.A.

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Indications & Clinical Uses

Ibuprofen acts systemically to alleviate symptoms associated with inflammatory and febrile conditions in children.

  • Pain: Provides relief from mild to moderate acute pain such as headache, toothache, or postoperative discomfort.
  • Fever: Reduces elevated body temperature associated with viral or bacterial infections.
  • Inflammation: Decreases swelling and discomfort in minor musculoskeletal injuries or soft‑tissue inflammation.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it diminishes peripheral sensitization of nociceptors, reduces vasodilation and edema, and lowers the hypothalamic set‑point for temperature regulation, thereby providing analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Ibuprofen may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin reactions: mild rash or itching.
  • Local irritation: rectal burning or discharge.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or failure.
  • Anaphylactic or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity or severe liver injury.

Precautions & Warnings

When using ibuprofen rectal suppositories, certain precautions should be observed to ensure safe and effective therapy.

  • Age and weight: Use only in children for whom the prescriber has determined an appropriate dose based on age and body weight.
  • Hypersensitivity: Avoid if the patient has known allergy to ibuprofen or other NSAIDs.
  • Gastrointestinal risk: Caution in children with a history of peptic ulcer disease or gastrointestinal bleeding.
  • Renal function: Monitor renal status in patients with dehydration, renal impairment, or concurrent nephrotoxic drugs.
  • Concomitant medications: Use carefully with anticoagulants, corticosteroids, or other NSAIDs to reduce bleeding risk.
  • Store below 25°C: Keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in volume‑depleted patients.
  • Diuretics: potential for decreased antihypertensive effect and renal impairment.
  • Lithium: ibuprofen can raise lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Frequently Asked Questions

Momentkid Prima Infanzia is a pediatric ibuprofen formulation designed to relieve mild to moderate pain, reduce fever, and lessen inflammation in children when oral dosing is not suitable. It is commonly employed for conditions such as headache, toothache, postoperative discomfort, and febrile illnesses.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signaling, and reset the hypothalamic temperature set‑point, providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of ibuprofen for a child is set by the prescribing healthcare professional based on the child’s age, weight, and the specific condition being treated. Dosage guidelines are typically expressed in milligrams per kilogram of body weight, and the prescriber will select the exact amount and frequency.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects. Breastfeeding mothers should consult a healthcare provider, as small amounts can pass into milk. Professional guidance is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Momentkid Prima Infanzia. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Ibuprofen and acetaminophen both reduce fever and relieve pain, but ibuprofen also possesses anti‑inflammatory properties due to COX inhibition, whereas acetaminophen does not significantly affect inflammation. Ibuprofen may cause gastrointestinal irritation, while acetaminophen carries a risk of liver toxicity at high doses. Choice depends on the clinical scenario and patient tolerance.

Momentkid Prima Infanzia should be stored below 25 °C in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain stability. Do not freeze the suppositories, and keep them out of reach of children.

The product is supplied as a rectal suppository. After washing hands, the appropriate dose is gently inserted into the rectum, preferably after a bowel movement, with the child lying on their side. The suppository should be placed past the anal sphincter to ensure absorption. Follow the prescriber’s instructions for timing and frequency.

Serious adverse events include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and rare skin disorders like Stevens‑Johnson syndrome. If any signs of severe abdominal pain, blood in stool, swelling, rash, or breathing difficulty occur, seek medical attention immediately.

Ibuprofen rectal suppositories should be avoided in children with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe renal or hepatic impairment, and in those receiving anticoagulant therapy without close monitoring. Consultation with a healthcare professional is required before use in these populations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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