Product image of Momesonex (Mometasone Furoate) supplied by GNH India

Momesonex

Active Ingredient:
Mometasone Furoate
Origin:
EU

Momesonex (Mometasone Furoate)

Mometasone furoate, the active ingredient in Momesonex, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis and nasal polyps in appropriate patient populations.
GNH India supplies Momesonex as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma B.V.

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Indications & Clinical Uses

Momesonex is a nasal corticosteroid that acts on inflammatory processes of the nasal mucosa.

  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and rhinorrhea.
  • Nasal polyps: decreases polyp size and improves nasal airflow.
  • Seasonal allergic rhinitis: alleviates symptoms triggered by seasonal allergens.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, forming a receptor complex that translocates to the nucleus. This complex modulates gene transcription, suppressing pro‑inflammatory cytokines, chemokines and adhesion molecules, thereby reducing inflammation and edema of the nasal mucosa.

Side Effects

Momesonex may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation
  • Epistaxis (nosebleeds)
  • Headache
  • Throat irritation or dryness
  • Cough
  • Altered taste or bitter taste

Serious or Rare Side Effects

  • Nasal septal perforation
  • Severe allergic reaction (anaphylaxis)
  • Vision changes or cataract formation
  • Adrenal suppression with systemic exposure
  • Opportunistic fungal infection of the nasal passages

Precautions & Warnings

Before using Momesonex, consider the following precautions.

  • Pediatric use: follow age‑specific dosing recommendations.
  • Active nasal infection: avoid until infection resolved.
  • Glaucoma or cataract: monitor intra‑ocular pressure.
  • Concomitant nasal steroids: do not use multiple nasal corticosteroids simultaneously.
  • Systemic corticosteroid therapy: assess risk of systemic effects.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Momesonex may interact with other medicines.

Major Interactions (Avoid)

  • Systemic corticosteroids: increased risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may raise local drug exposure.
  • Live vaccines: potential reduction in vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (e.g., fluconazole): may modestly increase exposure.
  • Ritonavir or other potent CYP3A4 inhibitors: monitor for local irritation.
  • Nasal decongestants (e.g., oxymetazoline): may increase nasal irritation.

Frequently Asked Questions

Momesonex is a prescription nasal spray containing mometasone furoate. It is indicated for the treatment of allergic rhinitis and for reducing the size of nasal polyps, helping to improve nasal breathing and relieve associated symptoms such as congestion, sneezing, and itching.

Mometasone furoate is a potent glucocorticoid receptor agonist. After binding to intracellular receptors in nasal mucosal cells, it modulates gene expression to suppress the release of inflammatory mediators, decreasing swelling, mucus production, and immune cell infiltration in the nasal passages.

The exact dosing regimen for Momesonex is determined by the prescribing healthcare professional. Typically, the label recommends one or two sprays per nostril once daily, but the prescriber may adjust the dose based on the patient’s age, severity of symptoms, and clinical response.

The safety of mometasone furoate nasal spray in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Momesonex.

To order Momesonex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Momesonex (mometasone furoate) is a high‑potency nasal corticosteroid with a low systemic bioavailability, similar to fluticasone propionate and budesonide. Clinical studies suggest comparable efficacy in controlling allergic rhinitis, while its once‑daily dosing may improve adherence relative to some alternatives.

Momesonex should be stored at room temperature, below 25 °C, in its original packaging. Protect the spray from moisture and direct sunlight. Keep the device upright and do not expose it to extreme temperatures, which could affect spray performance.

Before first use, prime the spray by pressing the actuator several times until a fine mist appears. Tilt the head slightly forward, insert the tip into one nostril, close the opposite nostril with a finger, and spray the prescribed number of sprays while breathing in gently. Repeat in the other nostril if directed.

Serious adverse events, although rare, include nasal septal perforation, severe allergic reactions such as anaphylaxis, vision changes (including cataract formation), adrenal suppression with prolonged high‑dose use, and opportunistic fungal infections of the nasal cavity. Patients should seek medical attention if any of these occur.

Momesonex is contraindicated in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It should also be avoided in patients with active untreated nasal infections, recent nasal surgery, or those who are already using another nasal corticosteroid without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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