Product image of Mometahexal (Mometasone Furoate) supplied by GNH India

Mometahexal

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometahexal (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometahexal, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis, seasonal and perennial forms, and nasal polyps in adults and children.

GNH India supplies Mometahexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Ag

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Indications & Clinical Uses

Mometasone furoate nasal spray is a glucocorticoid used to manage inflammatory conditions of the nasal passages.

  • Allergic rhinitis: reduces nasal congestion, itching and sneezing caused by allergic inflammation.
  • Seasonal allergic rhinitis: alleviates symptoms that flare during specific pollen seasons.
  • Perennial allergic rhinitis: controls year‑round nasal symptoms from continuous allergen exposure.
  • Nasal polyps: helps shrink polyps and improve nasal airflow.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and adhesion molecules, thereby reducing inflammatory cell migration and edema in the nasal mucosa.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Headache.
  • Epistaxis (nosebleeds).
  • Throat irritation or dryness.
  • Cough.
  • Altered taste or bitter taste.

Serious or Rare Side Effects

  • Nasal septal perforation.
  • Severe allergic reaction (anaphylaxis).
  • Vision changes or cataract formation.
  • Adrenal suppression with prolonged high‑dose use.
  • Opportunistic fungal infection of the nasal passages.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Assess for active nasal infection: avoid use until infection resolves.
  • Recent nasal surgery or trauma: postpone treatment to prevent impaired healing.
  • Do not exceed prescribed dose: higher doses increase risk of systemic effects.
  • Monitor for signs of systemic corticosteroid exposure, such as bruising or mood changes.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medicines.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic steroid levels.
  • Systemic corticosteroids: additive immunosuppressive effects.
  • Live vaccines: reduced vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., itraconazole): may increase local exposure.
  • Ritonavir or other protease inhibitors: may elevate steroid concentrations.
  • St. John’s wort: may decrease steroid effectiveness.

Frequently Asked Questions

Mometahexal is a nasal spray containing mometasone furoate and is indicated for the relief of symptoms associated with allergic rhinitis, both seasonal and perennial, as well as for the management of nasal polyps. It helps reduce congestion, itching, sneezing, and improves nasal airflow.

Mometasone furoate acts as a glucocorticoid receptor agonist. After binding to intracellular receptors, it alters gene transcription, suppressing the release of inflammatory cytokines and chemokines. This reduces inflammatory cell infiltration and edema in the nasal mucosa, leading to symptom relief.

The appropriate dose of Mometahexal is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for mometasone furoate nasal spray in pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against any possible risks. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their physician.

To request Mometahexal, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometahexal contains mometasone furoate, a high‑potency intranasal corticosteroid with minimal systemic absorption when used at recommended doses. Compared with older agents such as beclomethasone, it often provides comparable or superior symptom control with a lower risk of systemic side effects.

Store Mometahexal at room temperature, preferably below 25 °C. Keep the spray in its original packaging, protect it from moisture and direct heat, and ensure the cap is tightly closed when not in use.

Mometahexal is administered as a nasal spray. The patient should gently blow the nose, insert the nozzle into one nostril, and spray the prescribed number of sprays while breathing in gently. The process is repeated in the other nostril if directed by the prescriber.

Serious but rare risks include nasal septal perforation, severe allergic reactions such as anaphylaxis, adrenal suppression with prolonged high‑dose use, and opportunistic fungal infections of the nasal cavity. Patients should seek immediate medical attention if they notice unusual bleeding, persistent pain, or signs of systemic steroid effects.

Mometahexal should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active untreated nasal infections, recent nasal surgery, or trauma until healing is complete.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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