Product image of Mometason Apofri (Mometasone Furoate) supplied by GNH India

Mometason Apofri

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometason Apofri (Mometasone Furoate)

Mometasone Furoate, the active ingredient in Mometason Apofri, is a corticosteroid presented as a nasal formulation for intranasal use. It reduces nasal inflammation and is used to treat allergic rhinitis in adults and children.

GNH India supplies Mometason Apofri as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

  • Mometason Apofri, a nasal corticosteroid, is employed to manage inflammatory conditions of the nasal passages.
  • Allergic rhinitis: alleviates nasal congestion, itching and sneezing caused by seasonal or perennial allergens.
  • Nasal polyposis: reduces size of nasal polyps and improves airflow.
  • Seasonal allergic rhinitis: controls symptoms triggered by pollen exposure.
  • Perennial allergic rhinitis: provides year‑round relief from indoor allergen‑induced nasal symptoms.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal mucosal cells, altering gene transcription. This action suppresses the release of inflammatory mediators, decreases cytokine production, and reduces vascular permeability, leading to diminished nasal edema, mucus production, and allergic inflammation.

Side Effects

Mometason Apofri may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Headache.
  • Epistaxis (nosebleeds).
  • Throat irritation.
  • Unpleasant taste.
  • Cough.

Serious or Rare Side Effects

  • Nasal septal perforation.
  • Secondary fungal or bacterial infections of the nasal mucosa.
  • Elevated intra‑ocular pressure or glaucoma.
  • Adrenal suppression with prolonged high‑dose use.
  • Severe allergic reaction (anaphylaxis).
  • Vision changes.

Precautions & Warnings

  • Before using Mometason Apofri, consider the following safety measures.
  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Age restrictions: not recommended for children under two years of age.
  • Existing infections: monitor for fungal or bacterial nasal infections.
  • Surgery: inform the surgeon of nasal steroid use prior to procedures.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Mometason Apofri can interact with other medicines; awareness of these interactions helps maintain safety.

Major Interactions (Avoid)

  • Systemic corticosteroids: may increase systemic glucocorticoid exposure.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): can raise local drug concentrations.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., fluconazole): may modestly increase exposure.
  • Antihistamines: additive sedative effect is unlikely but monitor for increased drowsiness.
  • Live vaccines: nasal steroids may reduce vaccine efficacy.
  • Nasal decongestants: concurrent use may increase risk of nasal irritation.

Frequently Asked Questions

Mometason Apofri is a nasal corticosteroid indicated for the treatment of allergic rhinitis and related nasal inflammation, helping to relieve symptoms such as congestion, itching, sneezing, and runny nose.

Mometasone furoate binds to glucocorticoid receptors in nasal mucosal cells, modulating gene transcription to suppress inflammatory mediators, reduce swelling, and limit mucus production, thereby improving nasal airflow.

The prescribed dose of Mometason Apofri is determined by a qualified healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Patients should follow the prescriber’s instructions exactly.

Safety in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometason Apofri contains mometasone furoate, a potent corticosteroid with high local anti‑inflammatory activity and minimal systemic absorption, comparable to other nasal steroids such as fluticasone and budesonide, but may offer a different dosing schedule or formulation preference.

Store Mometason Apofri at room temperature, below 25 °C, in the original container, protected from moisture and direct sunlight. Do not freeze the product.

Mometason Apofri is administered as a nasal spray. The patient should gently blow the nose, insert the nozzle into each nostril, and spray the prescribed number of sprays while inhaling gently, then avoid blowing the nose for a few minutes.

Serious risks, though rare, include nasal septal perforation, secondary fungal or bacterial infections of the nasal mucosa, adrenal suppression with prolonged high‑dose use, and increased intra‑ocular pressure that could lead to glaucoma.

Individuals with known hypersensitivity to mometasone furoate or any component of the formulation, children under two years of age, and patients with active untreated nasal infections should avoid using Mometason Apofri unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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